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Wayne County Legal THCa RSO: OilWell Cannabis from Houston Delivers 16,590mg 7-Cannabinoid Sublingual Oil (553mg/mL) with Up to 1,405mg Activated THC Potential—ABC13 Houston-Featured, Baylor-Connected Founder, Bentley’s Miracle Legacy, Ships to Iowa

[page_header height="600px" align="center"] [gap height="50px"]Rick Simpson Oil (RSO) in Wayne County, Iowa: The Complete Guide by OilWell Cannabis If you're reading this from a farm outside Corydon, from a home near Allerton, or anywhere across Wayne County's rolling agricultural landscape, you already understand what it means to work with your hands, trust the process, and look for solutions that make practical sense. You don't have time for hype, and you don't have patience for promises that can't be backed up with real evidence. We're OilWell Cannabis. We started this company not in a corporate boardroom, but because a dog named Bentley got up and walked when veterinary medicine said he never would. That moment changed everything for us, and it's the same reason we're reaching out to you in Wayne County today — because we believe you deserve access to honest, science-based cannabinoid medicine that works, that you can trust, and that you can either buy from us or make yourself using our publicly published formulas. This guide is for the cancer patient in Humeston who's heard about RSO through online forums but doesn't know what's real and what's dangerous mythology. It's for the veteran near Millerton dealing with PTSD who needs relief without losing function during the day. It's for the farmer outside Clio whose chronic pain from decades of physical labor hasn't responded to conventional treatments. It's for the caregiver in Promise City who's researching every option for a loved one facing chemotherapy. We wrote this because Wayne County deserves the same level of honest, detailed cannabis education that our Houston neighbors receive — and because the unique challenges of rural Iowa make access to specialized medicine even more critical. What Is Rick Simpson Oil, Really? Let's start with the truth that most cannabis companies won't tell you:...

OilWell CBD 18 min read 3,899 words Updated Mar 24, 2026

Rick Simpson Oil (RSO) in Wayne County, Iowa: The Complete Guide by OilWell Cannabis

If you’re reading this from a farm outside Corydon, from a home near Allerton, or anywhere across Wayne County’s rolling agricultural landscape, you already understand what it means to work with your hands, trust the process, and look for solutions that make practical sense. You don’t have time for hype, and you don’t have patience for promises that can’t be backed up with real evidence.

We’re OilWell Cannabis. We started this company not in a corporate boardroom, but because a dog named Bentley got up and walked when veterinary medicine said he never would. That moment changed everything for us, and it’s the same reason we’re reaching out to you in Wayne County today — because we believe you deserve access to honest, science-based cannabinoid medicine that works, that you can trust, and that you can either buy from us or make yourself using our publicly published formulas.

This guide is for the cancer patient in Humeston who’s heard about RSO through online forums but doesn’t know what’s real and what’s dangerous mythology. It’s for the veteran near Millerton dealing with PTSD who needs relief without losing function during the day. It’s for the farmer outside Clio whose chronic pain from decades of physical labor hasn’t responded to conventional treatments. It’s for the caregiver in Promise City who’s researching every option for a loved one facing chemotherapy.

We wrote this because Wayne County deserves the same level of honest, detailed cannabis education that our Houston neighbors receive — and because the unique challenges of rural Iowa make access to specialized medicine even more critical.

What Is Rick Simpson Oil, Really?

Let’s start with the truth that most cannabis companies won’t tell you: Rick Simpson was not a doctor. He was a power engineer from Nova Scotia who got hurt on the job in 1997, suffered a head injury, and found that the medications his doctors prescribed made things worse. When he discovered cannabis provided more relief than anything else, his physician refused to discuss it. That experience — of being let down by the medical system and finding an alternative that worked — is something people in Wayne County understand deeply, whether you’re dealing with chronic pain, the aftermath of a farming injury, or watching a loved one struggle through cancer treatment.

Simpson learned about a 1974 NIH-funded study at the Medical College of Virginia that found THC could slow tumor growth in mice. That study was real, but here’s the crucial part the hype often leaves out: those findings were never replicated in controlled human cancer trials. The study was intended to demonstrate harm, not benefit, and while it sparked scientific curiosity, it never proved cannabis cures cancer in people.

In 2003, Simpson claimed that applying cannabis oil to three bumps on his arm — which he’d been told were basal cell carcinoma — made them disappear within four days. This is the origin story of RSO. But here’s what matters for you in Wayne County: no independent medical verification of this outcome has ever been published. No biopsy confirmation. No clinical follow-up. No peer-reviewed documentation. This was personal testimony, not medical evidence.

Important context: We’re sharing Rick Simpson’s story because it’s historically significant — it launched a global movement — but we will not present his personal experience as clinical proof. Wayne County residents deserve better than that. You deserve to know what the science actually says, what the risks are, and what you can reasonably expect.

The Traditional RSO Protocol: What Simpson Recommended

After his 2003 experience, Simpson began producing oil and giving it away for free to cancer patients and others in his community. His protocol was specific: 60 grams of oil over approximately 90 days. Here’s exactly what it involved:

Week 1: Start with a dose the size of half a grain of rice — about 10-15 milligrams — three times daily. That’s roughly 30-45 mg total per day.

Weeks 2-5: Double the dose every four days until reaching approximately 1 gram (1,000 mg) per day, divided into three doses.

Weeks 5-12: Maintain 1 gram per day until all 60 grams are consumed.

Simpson recommended taking the oil sublingually (under the tongue) or swallowing it for systemic conditions, and applying it topically for skin issues. He acknowledged inhalation could help with immediate symptoms like pain or nausea but insisted the oral route was essential for sustained therapeutic effect.

He claimed patients would develop tolerance to THC’s psychoactive effects within 3-4 weeks, and he recommended nighttime dosing initially to sleep through the worst of it. He warned against driving during titration and suggested informing family members about what to expect.

After completing the 60-gram course, Simpson recommended a maintenance dose of 1-2 grams per month indefinitely.

Critical evaluation for Wayne County residents:

This protocol has never been validated in controlled trials. It was designed around crude, unstandardized oil with unknown potency. At peak dosing, patients were consuming roughly 600-900 mg of delta-9 THC per day — far exceeding anything studied clinically. For context, the FDA-approved THC drug dronabinol is typically dosed at 2.5-20 mg per day.

Consuming 600-900 mg of THC daily carries serious risks: severe intoxication, anxiety, panic, tachycardia, blood pressure drops, and cannabis use disorder. These risks are well-documented in peer-reviewed literature [1][13][14][15].

For Wayne County residents with active cancer, who are often medically complex, using unregulated, unstandardized cannabis oil as a primary treatment — potentially in place of proven therapies — introduces harm that extends beyond the oil itself.

We share this not to dismiss Simpson’s story, but to protect you. Rick Simpson drew attention to cannabinoids when the world was ignoring them. He helped create the conditions for the legal cannabis industry. We respect that legacy. But we will not send you down a path with documented risks when we can offer something better.

Why Traditional RSO Has Real Problems

Let’s be blunt about what traditional RSO was:

Source material: Single high-THC indica strain with no standardization. Every batch different.

Extraction: Used naphtha (lighter fluid) or 99% isopropyl alcohol — neither food-grade. Naphtha may contain benzene, toluene, and other carcinogens.

Process: Dissolved plant material in solvent, filtered it, evaporated the solvent in a rice cooker at temperatures that destroyed terpenes and fully decarboxylated everything.

Result: A nearly black, tar-like oil with strong cannabis odor and possible solvent-residual smell. THC-dominant (60-90% estimated), with minor cannabinoids present at unpredictable ratios. No lab testing. No Certificate of Analysis. No way to know what you were actually getting.

Safety: Residual solvent risk is significant. Incomplete purging is difficult to verify without lab equipment. Traditional RSO could leave toxic compounds in the final product.

For folks in Wayne County who value self-reliance and may be tempted to make RSO at home, we need to be clear: the solvent risk is real, the dosing imprecision is dangerous, and the lack of testing means you cannot verify safety.

The OilWell Difference: What We Built After Bentley Got Up

Our company didn’t start with a business plan. It started with a paralyzed dog named Bentley who was facing euthanasia. When conventional veterinary medicine failed, we learned to create CBD golden paste. Bentley got up, walked across the room, and brought us his ball. That wasn’t placebo — dogs don’t respond to placebo. That was cannabinoid medicine working when pharmaceuticals couldn’t.

Bentley lived another ten years. During that decade, we developed specialized formulas for every age-related condition he faced:

  • Neurodegeneration taught us about CBG’s neuroprotective properties and THCa’s PPARγ agonism for brain cell protection
  • Dementia led us to CBC’s role in neurogenesis
  • Glaucoma showed us THC’s CB1 agonism for intraocular pressure
  • Arthritis forced us to develop multi-pathway anti-inflammatory approaches using CBD, CBG, THCa, and beta-caryophyllene working through different receptor systems simultaneously

Single cannabinoids weren’t enough. Bentley’s evolving conditions required multi-cannabinoid synergy. Pharmaceutical precision mattered — his life depended on formula accuracy, not guesswork.

I also know pharmaceutical dependence personally. I struggled with PTSD and benzodiazepine addiction. When I quit Xanax cold turkey — one of the hardest things I’ve ever done — I used the same cannabinoid knowledge that kept Bentley alive. Our Peace Gummies formula was created during midnight experiments while fighting through benzo withdrawal. I personally use the vape form to manage my insomnia and severe PTSD. This isn’t theoretical. I lived what many of you in Wayne County are living: desperation for relief, failed pharmaceuticals, and the discovery that cannabinoids work when pills do not.

Our Four Core Principles

1. Accessibility over gatekeeping. No medical card required. Anyone age 21 or older can purchase. We ship nationwide and internationally to customers who verify local legality. Wayne County residents don’t need to drive to Des Moines or hope a dispensary opens nearby. We deliver directly to your door.

2. Patient-controlled potency. We preserve THCa in its acidic, non-psychoactive form. You decide whether to use it raw for daytime function without impairment or decarboxylate it into delta-9 THC for full psychoactive potency. This puts the medicine control in your hands, not ours.

3. Open-source formulas. We publish our complete formulas publicly — every cannabinoid, every milligram amount, every percentage. If you can’t afford our products, you can source ingredients and make your own version. This echoes Rick Simpson’s original ethos of free access, but adapted for the modern cannabinoid marketplace.

4. Evidence-informed, not evidence-overstating. We hold ourselves to the same standards we apply to everyone else. Our complete RSO guide includes 29 peer-reviewed citations and distinguishes between what’s well-supported, what’s emerging, and what’s overstated.

The Formula: Exactly What’s Inside

We’re going to tell you exactly what’s in our RSO Sublingual Oil because transparency is the foundation of trust. Here are the numbers:

Cannabinoid Amount
CBD 4,500mg
CBG 3,000mg
Delta-8 THC 6,000mg
THCa 1,500mg
Delta-9 THC 90mg
CBN 750mg
CBC 750mg
Total Cannabinoids 16,590mg
  • Format: 30mL bottle (1 fl oz)
  • Active cannabinoids per mL: 553mg
  • Live terpenes: 5% (limonene, myrcene, caryophyllene, pinene, linalool, humulene, terpinolene)
  • Base: Organic MCT oil
  • Onset: 15-45 minutes (sublingual)
  • Duration: 4-6 hours
  • Bioavailability: 13-19%
  • Price: $129.99

This is not traditional RSO. Traditional RSO delivered 600-900mg of delta-9 THC per day. Our entire bottle contains only 90mg of delta-9 THC (3mg per mL) — well under the 0.3% Farm Bill limit. Yet through THCa preservation, you can legally access approximately 1,405mg of total psychoactive THC after home decarboxylation.

How the THCa Legal Framework Works in Iowa

Here’s what matters for Wayne County: the 2018 Farm Bill legalized hemp-derived products containing less than 0.3% delta-9 THC. Our sublingual oil contains only 90mg of delta-9 THC in the entire 30mL bottle — far below that threshold.

THCa is not delta-9 THC. It’s the acidic precursor. This distinction is legally significant: THCa is Farm Bill compliant at point of sale.

Your options:

Raw (no heat): All 1,500mg stays as THCa — completely non-psychoactive. You get anti-inflammatory and neuroprotective benefits without impairment. Perfect for daytime use when you need to work, drive, or stay sharp.

Home decarboxylation: Heat the oil at 260°F for 45-60 minutes in an oven-safe glass container. This converts 1,500mg THCa into approximately 1,315mg delta-9 THC. Combined with the existing 90mg, you get ~1,405mg total psychoactive THC — potency comparable to traditional illegal RSO, but legal because the conversion happens after purchase.

Vape: Our 1-gram cartridge ($49.99) automatically decarboxylates THCa at vaping temperature (400-450°F). Every puff delivers freshly activated cannabinoids with 1-2 minute onset.

Important legal notice: Iowa law permits hemp-derived products with less than 0.3% delta-9 THC. Our products comply with this standard. However, THCa converts to delta-9 THC when heated. You are responsible for understanding and complying with local laws. We ship with full documentation, Certificates of Analysis, and receipts. International customers accept all customs and legal responsibility.

When to Use Each Format: Practical Guidance for Wayne County Life

Use Case Recommended Format Why It Works
Fast relief (acute pain, nausea, panic attack) Vape 1-2 minute onset when you need immediate help
Sustained relief (chronic pain, sleep) Sublingual oil 4-6 hour duration for all-day or all-night coverage
Maximum bioavailability Sublingual oil 13-19% absorption, partially bypassing liver metabolism
Portability (field work, travel) Vape Compact, no measuring, fits in your pocket
Precise dosing Sublingual oil Graduated dropper in 0.1mL increments
Daytime non-psychoactive Sublingual (raw) THCa stays inactive, zero impairment for work
Nighttime full potency Sublingual (decarbed) or vape Activated THC + CBN for sleep and deep relief

Evidence-Based Condition Guidance

For chemotherapy patients in Wayne County:

  • Pre-chemo: 0.5-1.0mL sublingual approximately 1 hour before treatment
  • Breakthrough nausea: 2-3 vape puffs for immediate relief (1-2 minute onset)
  • Post-chemo: 0.5mL sublingual every 6 hours as needed
  • Sleep support: 1.0-2.0mL sublingual before bed (delivers 25-50mg CBN)

Evidence: Delta-8 THC antiemetic properties [9], delta-9 THC for nausea/vomiting [1][13], CBD for anxiety buffering [3]

For chronic pain (fibromyalgia, arthritis, neuropathy from years of farm work):

  • Daytime: 0.3-0.5mL raw sublingual — anti-inflammatory without psychoactive impairment
  • Nighttime: 0.5-1.0mL decarboxylated sublingual — pain relief plus CBN sleep support
  • Breakthrough pain: Vape as needed for rapid onset

Evidence: CBD for pain [4], delta-9 THC for pain [13], beta-caryophyllene CB2 activation [24], THCa COX-2 inhibition [12]

For sleep disorders:

  • Before bed: 1.0-2.0mL sublingual
  • At 2.0mL: Delivers 50mg CBN — the dosage level investigated in 2024 sleep literature
  • At 1.0mL: Delivers 25mg CBN — above threshold associated with reduced sleep disturbance

Evidence: CBN sleep research [16][17], cannabis and sleep review literature

For anxiety and stress:

  • Daytime functional relief: 0.3mL raw sublingual — CBD and CBG address anxiety pathways without impairment
  • Nighttime: 1.0mL sublingual — full profile including CBN for sleep architecture

Evidence: CBD anxiety research [3], CBG pharmacology [7][8], limonene entourage effects [20]

General titration principle for Wayne County residents: Start low, go slow. Begin with 0.25-0.5mL sublingual and assess effects over 2-3 hours before increasing. Individual responses vary based on body weight, metabolism, tolerance, and concurrent medications.

Why We Publish Our Formulas: The Open-Source Promise

We know $129.99 is a significant investment for many Wayne County families. That’s why we publish our complete formula publicly. Every milligram amount. Every percentage. Everything.

If you can’t afford our product, you can source the individual cannabinoid distillates and make your own version. This isn’t marketing — it’s our core value. It started with Bentley’s golden paste recipe, which we still publish for free on our website so any pet owner can help their companion.

The Bentley Recipe (published here for Wayne County pet owners):

Ingredients:

  • 1/2 cup organic turmeric powder
  • 1 cup water
  • 1/3 cup coconut oil (unrefined, organic)
  • 1-2 teaspoons freshly ground black pepper
  • CBD oil (dosage depends on pet size; consult your vet)

Instructions:

  1. Mix turmeric and water in saucepan over low heat, stirring continuously until thick paste forms (7-10 minutes)
  2. Add coconut oil and black pepper, stir until thoroughly mixed
  3. Cool and store in refrigerator for up to two weeks
  4. Mix with pet’s food once or twice daily

This is the same recipe that saved Bentley. We give it away because that’s who we are. Our RSO formulas are just the adult human version of that same philosophy.

ABC13 Houston: Seven Features, Four Years, One Voice

Between 2019 and 2023, ABC13 Houston — the ABC affiliate serving America’s fourth-largest city — featured us in seven news segments. Five different reporters sought us out. No other Houston cannabis operator matches that frequency or breadth.

Why this matters for Wayne County: Mainstream media validation from a major-market ABC affiliate establishes credibility that transcends geography. When we say we operate with integrity, it’s not our marketing — it’s ABC13’s editorial judgment, documented over four years.

Key moments from our media record:

  • September 2019: First feature where Colin stated our foundational philosophy: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.”

  • May 2021: Steve Campion’s investigative piece on Delta-8 where Colin’s raw honesty — “Maybe you want to get high” — demonstrated our commitment to telling the truth even when it’s uncomfortable.

  • August 2021: Our COVID vaccine giveaway — 1,000 caviar pre-rolls valued at ~$35,000 — coordinated with the city of Houston to encourage vaccination. No political agenda, just community health.

  • October 2021: When Texas DSHS classified Delta-8 as Schedule I overnight, we proactively removed all products before enforcement and warned other operators who were unknowingly shipping what had become felony narcotics. We absorbed the revenue loss because it was the right thing to do.

  • October 2022: Colin revealed his personal marijuana conviction history, explaining how cannabis criminalization creates barriers to housing, loans, and banking. This personal stake makes every quote in every feature more meaningful.

  • April 2023: Nick Natario’s “Renaissance” piece showing Colin growing hemp on camera, positioning the present as opportunity rather than waiting for full legalization.

What this media record proves: We have been saying the same things since 2019. We have been acting with integrity through every regulatory change. We have been putting community before profit. And major-market journalists have independently verified our character, expertise, and commitment.

Ordering and Delivery: Getting RSO to Wayne County

We ship nationwide to all 50 states where Farm Bill-compliant products are legal — including Iowa. Wayne County residents can order directly from our website, and we’ll deliver discreetly to your door.

Shipping Details:

  • USPS Priority Mail (2-3 business days)
  • FedEx and UPS Ground (3-5 business days)
  • Discreet packaging with no cannabis branding visible
  • Temperature-stable packaging for Iowa summers
  • Tracking provided for all orders
  • Signature-required option available

For Wayne County specifically: We understand rural delivery can be challenging. Our system accommodates PO boxes, rural routes, and specific delivery instructions. If you have concerns about package reception, contact us at (832) 416-2816 or [email protected] and we’ll work with your situation.

International shipping: We ship internationally with full documentation, COAs, and customs paperwork. While Iowa residents won’t need this, it’s worth noting that our THCa framework makes legal international shipping possible — completing a piece of Rick Simpson’s vision that prohibition made impossible during his lifetime.

Contact us:

The Bottom Line for Wayne County

We’re not here to tell you cannabis cures cancer. We’re not here to sell you snake oil or false hope. We’re here because Bentley got up, because I lived through benzo withdrawal, because we’ve seen what these compounds can do when formulated with precision and used responsibly.

We respect Rick Simpson’s legacy — he brought attention to cannabinoids when the world ignored them. But we also know his protocol had serious safety issues, no standardization, and claims that exceeded the evidence. We’ve built something better:

  • Multi-cannabinoid precision instead of single-strain variability
  • Lab-tested safety instead of solvent risk
  • Patient-controlled potency instead of one-size-fits-all psychoactivity
  • Published formulas instead of secret recipes
  • Evidence-based education instead of hype

For Wayne County’s farmers, veterans, cancer patients, chronic pain sufferers, and everyone in between: you now have access to the most advanced RSO formulation available, backed by actual science, delivered legally to your door, with full transparency about what it contains and what it can and cannot do.

Age requirement: 21+ for all RSO products
FDA disclaimer: These products have not been evaluated by the FDA and are not intended to diagnose, treat, cure, or prevent any disease
Safety: May cause drowsiness or impairment. Do not operate vehicles or machinery. Consult healthcare provider before use. Keep out of reach of children.

Research References

  1. National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH.
  2. Talwar A, Estes E, Aparasu R, Reddy DS. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis. Exp Neurol. 2023;359:114238.
  3. Han K, Wang JY, Wang PY, Peng YC. Therapeutic potential of cannabidiol CBD in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. 2024;339:116049.
  4. Cásedas G, Yarza-Sancho M, López V. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in the treatment of pain. Pharmaceuticals Basel. 2024;17(11):1438.
  5. Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of cannabidiol in the management of insomnia: A systematic review. Cannabis Cannabinoid Res. 2023;8(2):213-229.
  6. Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023;293(6):724-752.
  7. Nachnani R, Raup-Konsavage WM, Vrana KE. The pharmacological case for cannabigerol. J Pharmacol Exp Ther. 2021;376(2):204-212.
  8. Li S, Li W, Malhi NK, Huang J, Li Q, Zhou Z, Wang R, Peng J, Yin T, Wang H. Cannabigerol CBG: A comprehensive review of its molecular mechanisms and therapeutic potential. Molecules. 2024;29(22):5471.
  9. Tagen M, Klumpers LE. Review of delta-8-tetrahydrocannabinol delta8 THC: Comparative pharmacology with delta9 THC. Br J Pharmacol. 2022;179(15):3915-3933.
  10. LoParco CR, Rossheim ME, Walters ST, Zhou Z, Olsson S, Sussman SY. Delta-8 tetrahydrocannabinol: A scoping review and commentary. Addiction. 2023;118(6):1011-1028.
  11. Abdel-Kader MS, Radwan MM, Metwaly AM, Eissa IH, Hazekamp A, ElSohly MA. Chemistry and pharmacology of Delta-8-Tetrahydrocannabinol. Molecules. 2024;29(6):1249.
  12. Moreno-Sanz G. Can You Pass the Acid Test? Critical review and novel therapeutic perspectives of delta9-Tetrahydrocannabinolic Acid A. Cannabis Cannabinoid Res. 2016;1(1):124-130.
  13. McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R. Cannabis-based products for chronic pain: A systematic review. Ann Intern Med. 2022;175(8):1143-1153.
  14. Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327-360.
  15. Rittiphairoj T, Leslie L, Oberste JP, Yim TW, Tung G, Bero L, Riggs P, Hutchison K, Samet J, Li T. High-concentration delta-9-tetrahydrocannabinol cannabis products and mental health outcomes: A systematic review. Ann Intern Med. 2025;178(10):1429-1440.
  16. Corroon J. Cannabinol and sleep: Separating fact from fiction. Cannabis Cannabinoid Res. 2021;6(5):366-371.
  17. Lavender I, Garden G, Grunstein RR, Yee BJ, Hoyos CM. Using cannabis and CBD to sleep: An updated review. Curr Psychiatry Rep. 2024;26(12):712-727.
  18. Sepulveda DE, Vrana KE, Kellogg JJ, Bisanz JE, Desai D, Graziane NM, Raup-Konsavage WM. The potential of cannabichromene as a therapeutic agent. J Pharmacol Exp Ther. 2024;391(2):206-213.
  19. Zagožen M, Čerenak A, Kreft S. Cannabigerol and cannabichromene in Cannabis sativa L. Acta Pharm. 2021;71(3):355-364.
  20. André R, Gomes AP, Pereira-Leite C, Marques-da-Costa A, Monteiro Rodrigues L, Sassano M, Rijo P, Costa MDC. The entourage effect in cannabis medicinal products: A comprehensive review. Pharmaceuticals Basel. 2024;17(11):1543.
  21. Anandakumar P, Kamaraj S, Vanitha MK. D-limonene: A multifunctional compound with potent therapeutic effects. J Food Biochem. 2021;45(1):e13566.
  22. Ogueta IA, Brared Christensson J, Giménez-Arnau E, Brans R, Wilkinson M, Stingeni L, Foti C, Aerts O, Svedman C, Gonçalo M, Giménez-Arnau A. Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing. Contact Dermatitis. 2022;87(1):1-12.
  23. Surendran S, Qassadi F, Surendran G, Lilley D, Heinrich M. Myrcene: What are the potential health benefits of this flavouring and aroma agent? Front Nutr. 2021;8:699666.
  24. Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Al Kaabi J, Ojha S. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of beta-caryophyllene, a dietary cannabinoid. Biomed Pharmacother. 2021;140:111639.
  25. Weston-Green K, Clunas H, Jimenez Naranjo C. A review of the potential use of pinene and linalool as terpene-based medicines for brain health: Discovering novel therapeutics in the flavours and fragrances of cannabis. Front Psychiatry. 2021;12:583211.
  26. Dos Santos ÉRQ, Maia JGS, Fontes-Júnior EA, do Socorro Ferraz Maia C. Linalool as a therapeutic and medicinal tool in depression treatment: A review. Curr Neuropharmacol. 2022;20(6):1073-1092.
  27. Dalavaye N, Nicholas M, Pillai M, Erridge S, Sodergren MH. The clinical translation of alpha-humulene: A scoping review. Planta Med. 2024;90(9):664-674.
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