Coffee County Alabama Legal THCa Rick Simpson Oil by Houston’s OilWell Cannabis: Bentley’s 10-Year Miracle Legacy Drives 16,590mg 7-Cannabinoid RSO Sublingual Formula with 1,500mg Patient-Controlled THCa-to-THC Potency & Up to 1,405mg Total Activated Delta-9 THC Potential, ABC13 Houston-Featured Since 2019 & Baylor-Connected Founder, Farm Bill-Compliant Hemp-Derived with Nationwide Shipping

Rick Simpson Oil in Coffee County, Alabama: The Complete Guide by OilWell Cannabis

Coffee County sits in the heart of the Wiregrass region, where the red clay meets the pine flats and the values run deep. We know this area—Enterprise with its iconic boll weevil monument reminding us that transformation comes from struggle, Fort Rucker where our military community bears invisible wounds, and the quiet rural stretches where folks still believe in solving problems their own way when the system falls short. This guide is for you.

You’re here because you heard about Rick Simpson Oil—maybe from a fellow veteran at Rucker, a neighbor whose chronic pain finally found relief, or a caregiver searching for options when the doctors said there was nothing more to do. Whatever brought you here, we’re going to give you the full truth: what RSO actually is, what the science really says, what traditional RSO got wrong, and how we’ve spent ten years building something better—something we can legally deliver right here to your doorstep in Coffee County.

Who Rick Simpson Was—and Why His Story Still Matters Here

Rick Simpson wasn’t a doctor. He wasn’t a scientist. He was a power engineer from Nova Scotia—a working-class Canadian who got hurt on the job in 1997, suffered a head injury that left him with ringing ears and dizziness that wouldn’t quit, and found that the pills his doctors gave him made everything worse. When he asked his physician about cannabis, he got shut down cold. Sound familiar? In Coffee County, we know what it’s like when the medical establishment tells you no, when you’re left to figure it out yourself.

Simpson’s pivotal moment came in 2003 when he claimed three bumps on his arm—diagnosed as basal cell carcinoma—disappeared after he applied homemade cannabis oil and bandaged them for four days. No biopsy confirmation. No independent medical verification. Just his word and the conviction that cannabis had saved him. That single story launched a global movement.

From his property in Maccan, Nova Scotia, Simpson began giving away oil for free. He used high-THC indica strains, extracted with naphtha or isopropyl alcohol in a rice cooker, and produced a thick, black, tar-like oil that he distributed to cancer patients, chronic pain sufferers, and anyone who asked. No charge. No profit. Just the oil and his protocol: 60 grams over 90 days, starting with a dose the size of half a grain of rice and building up to a gram a day.

He called it Run From The Cure—the title of his 2005 documentary that spread the RSO story worldwide. The RCMP raided him twice. He was charged with cultivation, possession, and trafficking. Eventually, he left Canada for Europe, where he continued his advocacy. In 2012, he published Phoenix Tears: The Rick Simpson Story, documenting his method and philosophy .

Important context for Coffee County readers: Simpson’s story is historically significant, but it’s personal testimony, not medical evidence. We respect what he started—he put cannabinoids on the map when nobody else would talk about them—but we also know that what worked for one man in Nova Scotia in 2003 isn’t necessarily safe or effective for your neighbor in Enterprise dealing with cancer or your cousin in New Brockton struggling with PTSD. The doses he recommended—600 to 900 milligrams of THC per day at peak—were never studied in controlled human trials and carry real risks of severe intoxication, anxiety, panic, and cannabis use disorder [1][13][14][15].

Traditional RSO: What It Actually Was

Let’s be brutally honest about what traditional RSO was, because too many products sold in Alabama and across the country slap “RSO” on the label without telling you what’s inside.

Source material: Single high-THC indica strain—no standardization, no consistency. What grew in one season might be completely different the next.

Extraction solvent: Naphtha (yes, lighter fluid) or 99% isopropyl alcohol. Neither is food-grade. Naphtha contains benzene, toluene, and other carcinogens. Incomplete purging leaves toxic residues you can’t see or taste.

Process: Cannabis soaked in a bucket, filtered through cheesecloth, evaporated in a rice cooker. The heat destroyed virtually all terpenes—the aromatic compounds that give cannabis its scent and may contribute to its effects.

Appearance: Nearly black, thick, tar-like, with a solvent-residual smell. Difficult to handle.

Cannabinoid profile: 60-90% delta-9 THC, fully decarboxylated. Minor cannabinoids (CBD, CBN, CBG, CBC) were present only at whatever natural ratios the strain provided—uncontrolled, unmeasured, never lab-verified.

Testing: None. No Certificate of Analysis. No potency verification. No contaminant screening for pesticides, heavy metals, or residual solvents.

This is what many people still think they’re buying when they see “RSO”—but in Coffee County, you deserve better. You deserve to know exactly what’s in your medicine, how it was made, and that it’s safe.

The Problem With Simpson’s 60-Gram Protocol

Simpson’s titration schedule—half a grain of rice three times daily, doubling every four days until you hit a gram a day—was designed for crude, variable oil. It was never validated in a clinical trial. At peak dosing, patients consumed roughly 600-900 mg of delta-9 THC daily, far exceeding anything studied in controlled settings. The FDA-approved synthetic THC drug dronabinol is dosed at 2.5 to 20 mg per day [13].

Real risks at those doses: severe intoxication, impairment, anxiety, panic, tachycardia, hypotension, and cannabis use disorder [1][14][15]. For cancer patients—already medically complex—that level of unregulated THC exposure is dangerous.

Post-protocol maintenance: Simpson recommended 1-2 grams per month indefinitely. But without standardized product, “maintenance” meant whatever the next batch happened to contain.

The protocol made sense in 2003 when there were no alternatives. But in 2025, for residents of Coffee County who can order a lab-tested, precisely formulated product delivered to their door, there’s a better way.

What Simpson Got Right—and Where He Overstated

Simpson was right that cannabinoids deserve serious biomedical research. He was right that the early 2000s medical establishment was dismissive of cannabis. He was right that patients deserve access. His advocacy helped create the legal cannabis industry we have today.

But he overstated the evidence. No human clinical trial has demonstrated that RSO or any cannabis oil cures cancer. The National Cancer Institute acknowledges preclinical studies showing THC and CBD can induce apoptosis and slow tumor growth in cell lines and animal models , but these have not translated to proven human cancer cures. The FDA has not approved any cannabis plant product for cancer treatment [1].

For Coffee County residents facing cancer: We honor Simpson’s spirit, but we urge you to work with your oncologist at Southeast Alabama Medical Center in Dothan or your specialist at the Texas Medical Center (where we deliver free). RSO may complement treatment, but it should never replace proven therapies like surgery, radiation, or chemotherapy.

The OilWell Story: From Bentley’s Miracle to Your Medicine Cabinet

OilWell Cannabis didn’t start in a boardroom. It started with a paralyzed dog named Bentley.

Colin Valencia, our founder, grew up in McAllen, Texas—right across from Reynosa, Mexico, in one of the most dangerous border regions in North America. By sixteen, he’d seen friends killed and imprisoned. He learned to hustle, but he chose cannabis over harder paths—not because it was safe, but because it was the only thing that didn’t destroy people completely.

When Bentley, Colin’s beloved companion, became paralyzed in his back legs, veterinarians recommended euthanasia. The pain medications would destroy his organs. Colin had moved tons of cannabis but had never heard of CBD until a rescue worker named Jessica asked: “You’ve moved how many tons of weed and you’ve never heard of CBD?”

That question changed everything. Colin created a CBD golden paste for Bentley. The result wasn’t a miracle—it was medicine. Bentley got up, walked over, and brought Colin his ball. Dogs don’t respond to placebo. That was ten years ago. Bentley lived to age twenty, and during those years, Colin developed multi-cannabinoid formulas for every condition Bentley faced: neurodegeneration (CBG), dementia (CBC), glaucoma (THC), arthritis (multi-pathway anti-inflammation).

We published that golden paste recipe for free because Simpson taught us that medicine should be accessible. If your dog in Coffee County needs it, you can make it yourself:

CBD Golden Paste for Pets:

• 1/2 cup organic turmeric powder
• 1 cup water
• 1/3 cup unrefined organic coconut oil
• 1-2 tsp freshly ground black pepper
• CBD oil (dose per your vet’s guidance)

Mix turmeric and water over low heat into a paste (7-10 minutes). Add coconut oil and pepper. Cool, store refrigerated up to two weeks. Mix into food.

That same ethos—real solutions, published formulas, no gatekeeping—defines our RSO products today.

From Software Engineering to Baylor College of Medicine

Colin didn’t just learn cannabis on the border. He became a formally trained software engineer and did custom development for Baylor College of Medicine in the Texas Medical Center—the largest medical complex in the world, treating over 10 million patients annually. That combination of deep plant knowledge and medical-grade technical precision is what makes OilWell different.

When Colin developed PTSD and benzodiazepine addiction, he quit Xanax cold turkey using the same cannabinoid knowledge that saved Bentley. The Peace Gummies formula—now one of our most popular products—was created during midnight experiments while fighting through benzo withdrawal. Colin personally uses the vape form for insomnia and severe PTSD. This isn’t theoretical. This is lived experience.

Seven ABC13 Features: Houston’s Voice, Coffee County’s Proof

Between 2019 and 2023, ABC13 Houston featured Colin and OilWell in seven news segments. Five different reporters sought us out because when Houston needed to explain cannabis to its viewers, they called us.

September 2019: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.”

March 2021: “Pain comes in a lot of different forms.” We helped entrepreneur Jonathan Pina launch his mobile cannabis business—because we build ecosystems, not just brands.

May 2021: Steve Campion asked about Delta-8. Colin’s answer: “Maybe you want to get high.” Radical honesty. No PR filter. That’s what you get with OilWell.

August 2021: We gave away 1,000 caviar pre-rolls—$35,000 in product—to encourage COVID vaccination. We coordinated with the city of Houston. No political agenda. Just community health.

October 2021: Texas banned Delta-8 overnight. Colin removed all products before enforcement began and warned other operators they were unknowingly shipping Schedule I narcotics. We absorbed the loss. We led ethically.

October 2022: President Biden announced marijuana pardons. We debuted our CBD vending machine. And for the first time publicly, Colin revealed his personal marijuana conviction history. “I would love to see people not get hurt for this anymore.”

April 2023: On 4/20, we showed our hemp field and framed this moment as a Renaissance. “Right now is actually a pretty important time that should be enjoyed now.”

This media record—seven features, five reporters, four years—is independently verified credibility. You can’t buy that. You earn it.

The OilWell RSO Philosophy: Four Pillars

1. Accessibility Over Gatekeeping

In Coffee County, you don’t need a medical card. You don’t need a qualifying condition. You just need to be 21 or older. We ship to Enterprise, Elba, New Brockton, Kinston—every corner of Coffee County and beyond. While Alabama’s medical cannabis program remains restrictive (only 10,000 active patients compared to Florida’s 700,000), our Farm Bill-compliant products are accessible to any adult who needs them.

2. Patient-Controlled Potency

Our sublingual oil contains 1,500 mg of THCa—the acidic, non-psychoactive precursor to THC. You decide whether to use it raw (zero impairment, perfect for daytime use around Fort Rucker or operating farm equipment) or decarboxylate it at home (full psychoactive potency, ideal for nighttime relief).

How decarboxylation works: Heat the oil at 260°F for 45-60 minutes. This converts 1,500 mg THCa into approximately 1,315 mg delta-9 THC. Combined with the existing 90 mg delta-9 THC, you get ~1,405 mg total delta-9—comparable to traditional illegal RSO, but created legally in your kitchen in Coffee County.

Three usage options:

• Raw: Non-psychoactive anti-inflammatory for daytime use
• Activated: Full-potency therapeutic effects for nighttime
• Vape: Instant decarboxylation, 1-2 minute onset for breakthrough symptoms

3. Open-Source Formulas

We publish every milligram. If you can’t afford our products, you can source the ingredients and make your own. That’s not marketing—it’s our promise to Coffee County.

4. Evidence-Informed, Not Evidence-Overstating

The 29 peer-reviewed references in this document? We stand by every one. We tell you what’s proven, what’s promising, and what’s overstated. No snake oil.

Farm Bill Compliance: Why This Is Legal in Coffee County

The 2018 Farm Bill legalized hemp-derived products containing less than 0.3% delta-9 THC by dry weight. Our sublingual oil contains only 90 mg delta-9 THC in a 30 mL bottle—3 mg/mL—well under the federal limit. All cannabinoids are hemp-derived.

THCa is the key: At point of sale, THCa is not delta-9 THC. It’s Farm Bill compliant. You control the conversion. The product ships legally to Coffee County with full documentation, COAs, and receipts. You accept legal responsibility for decarboxylation decisions.

We ship nationwide and internationally. When you order from Enterprise or Elba, you get the same product we deliver to the Texas Medical Center.

Solvent-Free Production: Why It Matters

Traditional RSO used naphtha or isopropyl alcohol—toxic, non-food-grade solvents that leave carcinogenic residues. We don’t extract. We formulate.

Our process blends individual cannabinoid distillates and isolates in a controlled environment—no solvents, no risk. The carrier is organic MCT oil, neutral-tasting and easy to absorb. Third-party lab testing covers potency, terpenes, pesticides, heavy metals, residual solvents, and microbes. Certificates of Analysis are available for every batch.

For Coffee County residents who’ve heard horror stories about contaminated products, this is your guarantee: what’s on the label is what’s in the bottle.

The Two Product Formats: Which Is Right for You?

RSO Sublingual Oil — $129.99

Specs:

• 30 mL bottle (1 fl oz)
• 16,590 mg total cannabinoids (553 mg/mL)
• Seven cannabinoids: CBD 4,500 mg, CBG 3,000 mg, delta-8 THC 6,000 mg, THCa 1,500 mg, delta-9 THC 90 mg, CBN 750 mg, CBC 750 mg
• Live terpenes at 5%: limonene, myrcene, caryophyllene, pinene, linalool, humulene, terpinolene
• Organic MCT oil base
• Graduated dropper (0.1 mL increments)
• Onset: 15-45 minutes
• Duration: 4-6 hours
• Bioavailability: 13-19%
• 40-60 doses per bottle

Best for: Sustained relief, precise dosing, daytime non-psychoactive use (raw), nighttime activated use.

RSO Vape Cartridge — $49.99

Specs:

• 1-gram cartridge
• 900+ mg total cannabinoids
• Same six-cannabinoid ratio (no separate delta-9 THC—auto-decarbs when vaped)
• Live terpenes at 5%+
• 510-thread universal battery compatibility
• Onset: 1-2 minutes
• Duration: 2-4 hours
• Bioavailability: 10-35%

Best for: Breakthrough pain, acute nausea, panic attacks, immediate relief.

When to Use Each Format

Condition-Specific Guidance for Coffee County

Important disclaimer: These are informed by research, not prescriptions. Consult your healthcare provider. Our products are not FDA-approved to diagnose, treat, cure, or prevent any disease.

Chemotherapy-Related Nausea & Appetite

Coffee County residents traveling to SAMC in Dothan or TMC in Houston for cancer treatment can use:

• Pre-chemo: 0.5-1.0 mL sublingual 1 hour before treatment
• Breakthrough nausea: 2-3 vape puffs (1-2 minute relief)
• Post-chemo: 0.5 mL sublingual every 6 hours
• Sleep: 1-2 mL sublingual at bedtime (25-50 mg CBN)

Evidence: Delta-8 THC antiemetic effects [9], delta-9 THC for chemo nausea [1][13], CBD for anxiety buffering [3].

Chronic Pain (Fibromyalgia, Arthritis, Neuropathy)

For the farmers, factory workers, and veterans across Coffee County:

• Daytime: 0.3-0.5 mL raw sublingual—anti-inflammatory without impairment
• Nighttime: 0.5-1.0 mL decarboxylated sublingual—adds CBN for sleep
• Breakthrough: Vape as needed

Evidence: CBD for pain [4], delta-9 THC for pain [13], caryophyllene CB2 activation [24], THCa COX-2 inhibition [12].

Sleep Disorders

If the quiet of rural nights still doesn’t bring rest:

• Before bed: 1-2 mL sublingual
• 2 mL delivers 50 mg CBN—the dosage studied in 2024 sleep research
• 1 mL delivers 25 mg CBN—above the threshold for reduced sleep disturbance

Evidence: CBN sleep literature [16][17].

PTSD & Anxiety

For our Fort Rucker community and trauma survivors:

• Daytime functional: 0.3 mL raw sublingual—CBD and CBG without impairment
• Nighttime: 1.0 mL sublingual—full profile with CBN for sleep architecture

Evidence: CBD for anxiety [3], CBG pharmacology [7][8], limonene entourage effects [20].

Competitive Comparison: Why OilWell Beats Local Alternatives

OilWell vs. Alabama Medical Cannabis Program

Bottom line: Alabama’s program serves ~10,000 patients. Florida’s serves 700,000. If you don’t qualify or can’t travel, OilWell provides legal access.

OilWell vs. Hemp CBD Products

Bottom line: 16x more cannabinoid content, with psychoactive option you control.

How to Get OilWell RSO in Coffee County

We deliver. We ship. We make it simple.

Nationwide Shipping:

• USPS Priority Mail (2-3 days)
• FedEx/UPS Ground (3-5 days)
• Discreet packaging—no cannabis branding
• Tracking provided
• Temperature-stable for Alabama summers

International Shipping:

• Full documentation and COAs for customs
• Customer accepts legal responsibility
• Contact us at (832) 416-2816 or [email protected]

For Coffee County specifically:

• Orders placed by 2 PM Central ship same day
• Arrives in Enterprise, Elba, New Brockton typically within 3-5 business days
• No need to drive to Dothan or Montgomery
• No need to qualify for a medical card

The Evidence Behind Every Milligram

This document includes 29 peer-reviewed references. We don’t hide behind vague “proprietary blends.” Every cannabinoid and terpene is anchored to specific literature.

• CBD: 4,500 mg—backed by seizure evidence [2], anxiety meta-analysis [3], pain review [4]
• CBG: 3,000 mg—review-level evidence for neurologic interest [7][8]
• Delta-8 THC: 6,000 mg—comparative pharmacology shows real activity [9], safety concerns documented [10][11]
• THCa: 1,500 mg—non-psychoactive precursor, COX-2 inhibitor [12]
• Delta-9 THC: 90 mg—low-dose THC evidence [13], pharmacokinetics [14], high-concentration risks [15]
• CBN: 750 mg—weak sleep evidence [16][17], included at researched dose
• CBC: 750 mg—preclinical promise [18][19]

Terpene Profile (5% live terpenes):

• Limonene [20]-[22]
• Myrcene [20][23]
• Caryophyllene (CB2 agonist) [24]
• Pinene [20][25]
• Linalool [20][22][25][26]
• Humulene [20][27]
• Terpinolene [20][28]

Entourage Effect: Plausible but not proven in humans [20][29].

OilWell Cannabis: A Promise to Coffee County

We’re not here to follow trends. We’re here to set them. We’re not here to sell snake oil. We’re here to give you the best possible version so you can give it a fair shot.

From Bentley’s miracle to your medicine cabinet, from Houston’s Montrose district to your front door in Coffee County, we built this company on integrity, creativity, and the mission that started when a paralyzed dog got up and walked.

Order today:

• Website: oilwellcbd.com
• Phone: (832) 416-2816
• Email: [email protected]
• Instagram: @oilwellcbd

Business hours:

• Monday-Thursday: 10 AM – 7 PM Central
• Friday-Saturday: 10 AM – 10 PM Central
• Sunday: 10 AM – 4 PM Central

Legal Notice: These products contain less than 0.3% delta-9 THC and are Farm Bill compliant. THCa converts to delta-9 THC when heated. You are responsible for complying with Alabama law. Keep out of reach of children. Do not operate vehicles or machinery while impaired. Consult your physician before use, especially if pregnant, nursing, or taking medications.

References:

RS1. Simpson R. Phoenix Tears: The Rick Simpson Story. Simpson RamaDur LLC; 2012.

RS2. Laurette C, director. Run From The Cure: The Rick Simpson Story . 2005.

RS3. Simpson R. Instructions and dosing information published on phoenixtears.ca.

RS4. Velasco G, Sánchez C, Guzmán M. Towards the use of cannabinoids as antitumour agents. Nat Rev Cancer. 2012;12(6):436-444.

RS5. Guzmán M, Duarte MJ, Blázquez C, et al. A pilot clinical study of delta-9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer. 2006;95(2):197-203.

RS6. National Cancer Institute. Cannabis and Cannabinoids (PDQ)—Health Professional Version. NIH/NCI. Updated 2024.

1. National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH.

2. Talwar A, Estes E, Aparasu R, Reddy DS. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis. Exp Neurol. 2023;359:114238.

3. Han K, Wang JY, Wang PY, Peng YC. Therapeutic potential of cannabidiol CBD in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. 2024;339:116049.

4. Cásedas G, Yarza-Sancho M, López V. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in the treatment of pain. Pharmaceuticals Basel. 2024;17(11):1438.

5. Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of cannabidiol in the management of insomnia: A systematic review. Cannabis Cannabinoid Res. 2023;8(2):213-229.

6. Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023;293(6):724-752.

7. Nachnani R, Raup-Konsavage WM, Vrana KE. The pharmacological case for cannabigerol. J Pharmacol Exp Ther. 2021;376(2):204-212.

8. Li S, Li W, Malhi NK, Huang J, Li Q, Zhou Z, Wang R, Peng J, Yin T, Wang H. Cannabigerol CBG: A comprehensive review of its molecular mechanisms and therapeutic potential. Molecules. 2024;29(22):5471.

9. Tagen M, Klumpers LE. Review of delta-8-tetrahydrocannabinol delta8 THC: Comparative pharmacology with delta9 THC. Br J Pharmacol. 2022;179(15):3915-3933.

10. LoParco CR, Rossheim ME, Walters ST, Zhou Z, Olsson S, Sussman SY. Delta-8 tetrahydrocannabinol: A scoping review and commentary. Addiction. 2023;118(6):1011-1028.

11. Abdel-Kader MS, Radwan MM, Metwaly AM, Eissa IH, Hazekamp A, ElSohly MA. Chemistry and pharmacology of Delta-8-Tetrahydrocannabinol. Molecules. 2024;29(6):1249.

12. Moreno-Sanz G. Can You Pass the Acid Test? Critical review and novel therapeutic perspectives of delta9-Tetrahydrocannabinolic Acid A. Cannabis Cannabinoid Res. 2016;1(1):124-130.

13. McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R. Cannabis-based products for chronic pain: A systematic review. Ann Intern Med. 2022;175(8):1143-1153.

14. Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327-360.

15. Rittiphairoj T, Leslie L, Oberste JP, Yim TW, Tung G, Bero L, Riggs P, Hutchison K, Samet J, Li T. High-concentration delta-9-tetrahydrocannabinol cannabis products and mental health outcomes: A systematic review. Ann Intern Med. 2025;178(10):1429-1440.

16. Corroon J. Cannabinol and sleep: Separating fact from fiction. Cannabis Cannabinoid Res. 2021;6(5):366-371.

17. Lavender I, Garden G, Grunstein RR, Yee BJ, Hoyos CM. Using cannabis and CBD to sleep: An updated review. Curr Psychiatry Rep. 2024;26(12):712-727.

18. Sepulveda DE, Vrana KE, Kellogg JJ, Bisanz JE, Desai D, Graziane NM, Raup-Konsavage WM. The potential of cannabichromene as a therapeutic agent. J Pharmacol Exp Ther. 2024;391(2):206-213.

19. Zagožen M, Čerenak A, Kreft S. Cannabigerol and cannabichromene in Cannabis sativa L. Acta Pharm. 2021;71(3):355-364.

20. André R, Gomes AP, Pereira-Leite C, Marques-da-Costa A, Monteiro Rodrigues L, Sassano M, Rijo P, Costa MDC. The entourage effect in cannabis medicinal products: A comprehensive review. Pharmaceuticals Basel. 2024;17(11):1543.

21. Anandakumar P, Kamaraj S, Vanitha MK. D-limonene: A multifunctional compound with potent therapeutic effects. J Food Biochem. 2021;45(1):e13566.

22. Ogueta IA, Brared Christensson J, Giménez-Arnau E, Brans R, Wilkinson M, Stingeni L, Foti C, Aerts O, Svedman C, Gonçalo M, Giménez-Arnau A. Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing. Contact Dermatitis. 2022;87(1):1-12.

23. Surendran S, Qassadi F, Surendran G, Lilley D, Heinrich M. Myrcene: What are the potential health benefits of this flavouring and aroma agent? Front Nutr. 2021;8:699666.

24. Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Al Kaabi J, Ojha S. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of beta-caryophyllene, a dietary cannabinoid. Biomed Pharmacother. 2021;140:111639.

25. Weston-Green K, Clunas H, Jimenez Naranjo C. A review of the potential use of pinene and linalool as terpene-based medicines for brain health: Discovering novel therapeutics in the flavours and fragrances of cannabis. Front Psychiatry. 2021;12:583211.

26. Dos Santos ÉRQ, Maia JGS, Fontes-Júnior EA, do Socorro Ferraz Maia C. Linalool as a therapeutic and medicinal tool in depression treatment: A review. Curr Neuropharmacol. 2022;20(6):1073-1092.

27. Dalavaye N, Nicholas M, Pillai M, Erridge S, Sodergren MH. The clinical translation of alpha-humulene: A scoping review. Planta Med. 2024;90(9):664-674.

28. Menezes IO, Scherf JR, Martins AOBPB, Ramos AGB, Quintans JSS, Coutinho HDM, Ribeiro-Filho J, de Menezes IRA. Biological properties of terpinolene evidenced by in silico, in vitro and in vivo studies: A systematic review. Phytomedicine. 2021;93:153768.

29. Russo EB. Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364.