Rick Simpson Oil (RSO) in Indiana: The Complete Guide by OilWell Cannabis

If you’re in Indiana—whether you’re in Indianapolis helping a loved one through chemotherapy, a veteran in Fort Wayne managing PTSD, a farmer in rural LaPorte County dealing with chronic back pain, or a cancer patient in Evansville exploring every option—you’ve likely heard whispers about Rick Simpson Oil. Maybe you’ve seen “RSO” mentioned in online forums, or perhaps a friend from Bloomington shared a story about cannabis oil helping with sleep when nothing else worked. Here in the Hoosier State, where our communities value straight talk, practical solutions, and looking out for neighbors, you deserve honest answers about what RSO actually is, what the science really says, and how a modern, legal, professionally formulated version can be part of your wellness journey.

We are OilWell Cannabis, a Houston-based company founded on the belief that cannabis medicine should be accessible, transparent, and grounded in real science—not hype. While we’re proud Texans, our mission extends far beyond the Lone Star State. We’ve built a product and delivery system that serves people across America, including right here in Indiana, because we know that Hoosiers face the same challenges as everyone else: a loved one’s cancer diagnosis, the desperation of chronic pain that won’t quit, the sleepless nights of anxiety, and the trauma that lingers long after the uniform comes off. This guide is written specifically for you—our neighbors in Indiana—because you deserve the same level of detailed, evidence-based education that we’ve been providing to Houston’s medical community for years.

Understanding Rick Simpson Oil: The History Behind the Name

Who Was Rick Simpson?

Rick Simpson wasn’t a doctor, oncologist, or scientist. He was a power engineer from Nova Scotia—a blue-collar tradesman who, like many Hoosiers, worked with his hands and trusted practical solutions over complex theories. In 1997, Simpson suffered a serious head injury from a scaffolding fall while working at a hospital. The conventional medications prescribed for his post-concussion symptoms—tinnitus, dizziness, chronic pain—either didn’t help or made things worse. When he discovered cannabis provided relief, he asked his doctor to consider it as an option. The doctor refused .

That rejection resonates across Indiana, where many patients have felt dismissed by a medical system that sometimes prioritizes prescriptions over patient-reported outcomes. We’ve heard from countless Hoosiers who’ve been told “there’s nothing more we can do” or been handed another opioid prescription without discussion of alternatives. Simpson’s story matters because it’s the story of ordinary people finding extraordinary solutions when the system fails them.

Simpson’s pivotal moment came in 2003 when he was diagnosed with basal cell carcinoma. Rather than pursue conventional treatment, he applied concentrated cannabis oil directly to the lesions. According to his personal testimony, the bumps disappeared within four days. No independent medical verification, biopsy confirmation, or clinical follow-up was ever published . This is where the RSO movement was born—not in a lab, but in one man’s desperate attempt to save himself.

Important context for Indiana readers: Simpson’s account is personal testimony, not medical evidence. The absence of clinical documentation means these events cannot be evaluated as scientific proof. However, they are historically significant as the catalyst for a global movement. Here in Indiana, where we value both faith and facts, we honor the story while staying grounded in what science can actually verify.

The Crusade: How RSO Went Global

After his 2003 experience, Simpson committed himself to producing and giving away cannabis oil for free to cancer patients and others in need. He claimed to help people with conditions that plague Indiana communities: cancer, chronic pain, diabetes, infections, glaucoma, arthritis, depression, and insomnia . His story spread through the 2005 documentary Run From The Cure, which became foundational viewing in cannabis communities worldwide. In many ways, that documentary did for cannabis oil what the Indianapolis 500 did for auto racing—put an obscure concept on the world map.

But Simpson’s advocacy brought legal consequences. The Royal Canadian Mounted Police raided his property in 2005 and 2009. He was charged with cultivation, possession, and trafficking. Eventually, he left Canada for Europe, continuing his advocacy from abroad . This history matters for Indiana residents because it shows the legal risks that defined early cannabis advocacy—risks that Hoosiers have faced too. While Indiana hasn’t had the same high-profile raids as Canada, many here remember when cannabis possession meant serious criminal charges that could derail a life.

Simpson’s position remained uncompromising: he maintained that RSO could cure cancer and that pharmaceutical companies and government agencies were suppressing this knowledge. He believed he was fighting institutional corruption . That worldview—shared by many in the early cannabis movement—reflects a deep distrust of institutions that resonates in parts of Indiana where pharmaceutical companies’ role in the opioid crisis has left lasting scars.

The Traditional RSO Protocol: What Simpson Recommended

Simpson’s core treatment protocol was a 60-gram, 90-day regimen. For Indiana residents researching RSO online, this protocol appears everywhere—but few sources explain what it actually entails or its limitations.

The Goal: Consume 60 grams of concentrated cannabis oil over approximately 90 days.

The Titration Schedule:

• Week 1: Start with a dose the size of half a grain of rice (10-15mg) taken three times daily (total: 30-45mg/day)
• Weeks 2-5: Double the dose every four days, building toward 1 gram per day divided into three doses
• Weeks 5-12: Maintain 1 gram per day (approximately 600-900mg of THC daily) until all 60 grams are consumed

Administration Methods: Simpson recommended oral/sublingual as primary, topical for skin issues, and acknowledged inhalation for immediate symptom relief but not as primary treatment.

Critical Context for Indiana Readers:

This protocol was designed around crude, unstandardized material. There are no published randomized controlled trials validating it. The peak dosing phase delivers 600-900mg of delta-9 THC daily—far exceeding anything studied in controlled settings (for comparison, FDA-approved dronabinol is typically 2.5-20mg/day). At those doses, risks include severe intoxication, anxiety, tachycardia, and cannabis use disorder [1][13][14][15].

For Indiana cancer patients considering this protocol, it’s crucial to understand: this was never clinically validated. Using unregulated, unstandardized cannabis oil as a primary cancer treatment—potentially in place of proven therapies—carries genuine harm potential. Delayed or foregone treatment for treatable cancers is a documented concern . While we respect Simpson’s historical importance, we cannot endorse a protocol that lacks clinical validation and poses real safety risks.

What Traditional RSO Actually Was

Traditional RSO was defined by Simpson’s method, not lab standards:

• Source material: Single high-THC indica strains, no standardization
• Extraction: Naphtha (petroleum-based) or 99% isopropyl alcohol—neither food-grade
• Process: Bucket, solvent wash, filter, rice cooker evaporation
• Appearance: Nearly black, thick, tar-like oil with possible solvent-residual odor
• Cannabinoid profile: 60-90% THC, fully decarboxylated, no ratio control, never lab-verified
• Terpene content: Effectively destroyed by heat and solvent
• Standardization: None. Every batch was different
• Residual solvent risk: Naphtha may contain benzene, toluene, and carcinogens

This description matters for Indiana residents because many products sold as “RSO” in today’s market bear little resemblance to what Simpson actually made. The term has become generic . When you see “RSO” on a product in Indiana (if you can find it legally), you need to ask: is this the crude, unstandardized oil Simpson made, or is it a modern formulation that solves the problems traditional RSO had?

About OilWell Cannabis: Our Story and Mission

Bentley: The Dog Who Started Everything

Our company’s origin story isn’t a business plan—it was a dying dog named Bentley. Bentley was more than a pet; he was family. When veterinarians told us euthanasia was the only humane option for his paralysis and organ-destroying pain medications, we refused to accept that answer.

A rescue worker named Jessica asked the question that changed everything: “You’ve moved how many tons of weed and you’ve never heard of CBD?” That exposed a blind spot. We knew cannabis recreationally, but not medicinally.

We created a CBD golden paste formula for Bentley. It wasn’t a cure, but it was hope. And that hope delivered what veterinary medicine said was impossible: Bentley got up, walked over, and brought his ball to play. From paralyzed to playing fetch. This wasn’t placebo—dogs don’t respond to placebo. This was cannabinoid medicine succeeding where pharmaceuticals failed.

Bentley lived another ten years, dying naturally at age twenty. During those years, we developed specialized formulas for every condition he faced:

• Neurodegeneration led us to CBG’s neuroprotective properties and THCa’s PPARγ agonism for brain cell protection
• Dementia led us to CBC’s role in neurogenesis
• Glaucoma led us to THC’s CB2 agonism for intraocular pressure
• Arthritis led us to multi-pathway anti-inflammatory approaches using CBD, CBG, THCa, and beta-caryophyllene

What this means for Indiana pet owners: If you’re in Indianapolis, Fort Wayne, or anywhere in Indiana facing a similar crisis with a beloved animal, we’ve published Bentley’s exact golden paste recipe publicly on our website. It’s free. You can make it today. That same open-source philosophy extends to our human formulas—we publish everything.

From Personal Health Crisis to Professional Mission

Our founder, Colin Valencia, understands pharmaceutical dependence personally. Living with PTSD and benzodiazepine addiction, he used the cannabinoid knowledge from Bentley’s journey to quit Xanax cold turkey—a notoriously difficult and dangerous feat. The Peace Gummies formula that became one of our products was created during midnight experiments while fighting through benzo withdrawal. Colin personally uses the vape form to manage his insomnia and severe PTSD.

This isn’t theoretical knowledge. We’ve lived what our Indiana customers live: the desperation when pills fail, the discovery that cannabinoids work when nothing else does, the frustration with a medical system that often dismisses alternatives.

Over time, we’ve developed formulas that doctors use for conditions affecting Hoosiers: Crohn’s disease, IBS, ulcerative colitis, PTSD, benzo addiction, and insomnia. Our focus has always been making cannabis accessible and effective for everyone—including vegans, diabetics, and those with specific dietary needs.

Why ABC13 Houston Calls Us “Houston’s Go-To Cannabis Authority”

Between 2019 and 2023, ABC13 KTRK Houston featured us in seven distinct news segments. Five different reporters sought us out across topics spanning business, law, medicine, community health, and politics. When a major-market ABC affiliate repeatedly returns to the same source, it’s not marketing—it’s earned credibility.

September 2019: The Foundation
In our first feature, Colin delivered the quote that defines everything we do: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.” That philosophy—honest education over hype—guides every word in this guide for Indiana readers.

March 2021: Ecosystem Builder
We helped entrepreneur Jonathan Pina launch High Maintenance Edibles, a mobile vendor concept. Colin’s quote resonated across Texas and beyond: “Pain comes in a lot of different forms.” Here in Indiana, where industrial workers, farmers, and veterans face diverse pain challenges, that understanding is fundamental.

May 2021: Delta-8 Investigation
When ABC13 investigated Delta-8 THC, Steve Campion asked Colin why someone would want it. His unfiltered response—“Maybe you want to get high”—demonstrated the radical honesty that’s become our trademark. We don’t hide behind vague wellness language. We tell you what products do, what the risks are, and let you decide.

August 2021: Community Health Leadership
During the COVID pandemic, we gave away 1,000 caviar pre-rolls (approximately $35,000 in product) to encourage vaccination. We coordinated with the City of Houston, with no political agenda—just community health. That same community-first approach extends to Indiana: we’re not just selling products; we’re building a healthier society.

October 2021: Ethical Leadership During Crisis
When Texas abruptly banned Delta-8 overnight, we proactively removed all products before enforcement began. We warned other operators who were unknowingly shipping Schedule I narcotics. We absorbed a massive revenue loss because doing the right thing matters more than profit. That’s the kind of company Indiana can trust.

October 2022: Personal Stakes Revealed
In our most personal feature, Colin revealed his own marijuana conviction history. He explained the housing, banking, and employment challenges that follow a cannabis conviction. “I would love to see people not get hurt for this anymore.” This isn’t corporate posturing—it’s lived experience. When we say we understand what Indiana residents face, we mean it.

April 2023: Renaissance Framing
On 4/20/2023, we told ABC13: “Right now is actually a pretty—like Renaissance—pretty important time that should be enjoyed now.” For Indiana residents watching cannabis laws evolve in neighboring states like Illinois and Michigan, that perspective matters. The cannabis landscape is changing, and we’re helping lead that change responsibly.

The OilWell RSO Philosophy: Four Pillars for Indiana

Our RSO is not traditional Rick Simpson Oil. It’s a formulated, multi-cannabinoid product informed by the RSO tradition but deliberately evolved to solve the problems that limited Simpson’s original vision.

1. Accessibility Over Gatekeeping

In Indiana, where medical marijuana remains restricted and qualifying conditions are limited, our product offers something revolutionary: no medical card required. If you’re 21 or older in Indianapolis, Fort Wayne, Evansville, South Bend, or anywhere in Indiana, you can legally purchase our Farm Bill-compliant RSO.

We ship nationwide, including to every corner of Indiana—from the Kentucky border to the Michigan line, from the Ohio River to the Wabash. Whether you’re in a rural township or an urban neighborhood, the same product is available to you.

2. Patient-Controlled Potency

Traditional RSO was always psychoactive—Simpson’s heat-based extraction converted all THCa to delta-9 THC. Our formula includes 1,500mg of THCa in its raw, non-psychoactive form. You decide:

• Raw (no heat): Non-psychoactive, perfect for daytime use while working, driving, or parenting
• Decarboxylated (260°F for 45-60 minutes): Converts to ~1,315mg delta-9 THC for full psychoactive potency
• Vape: Instant decarboxylation at 400-450°F for immediate relief

This means the same legal product can function as either a non-psychoactive anti-inflammatory or full-potency cannabis medicine—entirely at your discretion. For Indiana residents who need to function during the day but want stronger relief at night, this flexibility is transformative.

3. Open-Source Formulas

We publish our complete formulas publicly—every cannabinoid, every milligram. If you’re in Indiana and can’t afford our products, you can source the ingredients and make your own version. This isn’t a marketing gimmick; it’s our values.

Bentley’s Golden Paste Recipe (the one that saved our dog) is free on our website. We give away the formula that started everything because healing shouldn’t be gated by price. For Indiana pet owners facing a similar crisis, this is immediate, actionable help.

4. Evidence-Informed, Not Evidence-Overstating

Rick Simpson operated without access to peer-reviewed literature. We have that access, and we use it to distinguish between what’s well-supported, what’s emerging, and what’s overstated. The rest of this guide provides that same honest education to Indiana readers.

Farm Bill Compliance: Why Our RSO Is Legal in Indiana

We know this is your first question: Is this legal in Indiana?

Yes, absolutely. Here’s why:

The 2018 Farm Bill legalized hemp and hemp-derived products containing less than 0.3% delta-9 THC by dry weight. Our RSO Sublingual Oil contains only 90mg of delta-9 THC in the entire 30mL bottle—3mg per mL—well under the federal threshold.

All cannabinoids in our formula are hemp-derived. The product ships legally to Indiana and all 50 states.

The THCa Advantage: THCa is the acidic, non-psychoactive precursor to THC. It’s not delta-9 THC, so it’s Farm Bill compliant at point of sale. Indiana law cannot preempt federal hemp law. You can legally purchase, possess, and transport our products.

Indiana-Specific Legal Note: THCa converts to delta-9 THC when heated. Indiana residents are responsible for understanding and complying with local laws regarding decarboxylation. We provide full documentation, Certificates of Analysis (COAs), and receipts with every shipment.

Our Formulas: What Indiana Residents Need to Know

RSO Sublingual Oil – $129.99

Specifications:

• Live Terpenes: 5% (limonene, myrcene, caryophyllene, pinene, linalool, humulene, terpinolene)
• Format: 30mL bottle with graduated dropper (0.1mL increments)
• Potency: 553mg total cannabinoids per mL
• Onset: 15-45 minutes (sublingual)
• Duration: 4-6 hours
• Bioavailability: 13-19%
• Doses: Approximately 40-60 per bottle

For Indiana residents: This delivers clinical-strength cannabinoid support in a precision-measured format. Whether you’re in Indianapolis dealing with chemotherapy side effects or in Gary managing chronic pain, you know exactly what you’re getting in every drop.

RSO Vape Cartridge – $49.99

Specifications:

• Live Terpenes: 5%+
• Format: 1g cartridge (510-thread universal battery compatible)
• Onset: 1-2 minutes (fastest delivery)
• Duration: 2-4 hours
• THCa: Auto-decarboxylates at vape temperature for immediate activation

For Indiana residents needing rapid relief: This is breakthrough pain management, acute nausea control, or panic attack intervention delivered in 60-120 seconds.

Terpene Profile: The Sensory Experience

Our seven-terpene profile is identical in both products:

• Limonene (citrus-bright) – brings a sunny, uplifting aroma
• Myrcene – earthy foundation
• Caryophyllene (β-caryophyllene – pepper/spice) – unique CB2 receptor interaction
• Pinene (forest-fresh) – crisp, clean notes
• Linalool (floral, lavender) – calming presence
• Humulene (earthy, woody) – depth and complexity
• Terpinolene (piney, fruity, sparkling) – bright finish

For Indiana residents familiar with our state’s forests, farmland, and seasonal changes, these terpenes connect to familiar natural aromas—the pine forests of Brown County, the orchards of southern Indiana, the lavender fields some of our neighbors cultivate.

When to Use Each Format: A Guide for Indiana Lifestyles

Condition-Specific Usage for Indiana Residents

Critical Disclaimer: These contexts are informed by research cited in our evidence section. They are not medical prescriptions, not FDA-approved, and not substitutes for professional medical care. Always consult your Indiana healthcare provider before using cannabinoid products, especially if you have a medical condition, take medications, are pregnant or nursing, or have health concerns. Do not operate vehicles or machinery while under the influence of psychoactive cannabinoids. These products are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary.

Chemotherapy-Related Nausea and Appetite Support

For Indiana cancer patients at IU Health Simon Cancer Center, Ascension St. Vincent Cancer Center, or community oncology practices:

• Pre-chemo: 0.5-1.0mL sublingual approximately 1 hour before treatment
• Acute breakthrough nausea: 2-3 vape puffs for immediate relief
• Post-chemo: 0.5mL sublingual every 6 hours as needed
• Sleep support: 1.0-2.0mL sublingual before bed (delivers 25-50mg CBN)

Evidence context: Delta-8 THC antiemetic research [9], delta-9 THC nausea control [1][13], CBD anxiety buffering [3]

Indiana connection: Many Hoosiers undergoing chemo struggle with nausea that prescription antiemetics don’t fully control. Our multi-cannabinoid approach addresses multiple pathways simultaneously.

Chronic Pain (Fibromyalgia, Arthritis, Neuropathy)

For Indiana’s industrial workers, farmers, and veterans:

• Daytime (working hours): 0.3-0.5mL raw sublingual—anti-inflammatory without psychoactive impairment. Perfect for operating equipment in Indiana’s agricultural sector or working a shift at one of our manufacturing plants.
• Nighttime: 0.5-1.0mL decarboxylated sublingual—combines pain relief with CBN for restorative sleep
• Breakthrough pain: Vape as needed for rapid onset

Evidence context: CBD pain research [4], delta-9 THC analgesia [13], beta-caryophyllene CB2 activation [24], THCa COX-2 inhibition [12]

Indiana reality: Our state has been hard-hit by the opioid crisis. Many chronic pain patients are seeking alternatives to prescription opioids. While our RSO isn’t an opioid replacement, it offers a multi-pathway approach to pain management that doesn’t carry the same dependency risks.

Sleep Support

For Indiana residents struggling with insomnia:

• Before bed: 1.0-2.0mL sublingual
• At 2.0mL, you receive 50mg CBN—the dosage level investigated in 2024 sleep literature [16][17]
• At 1.0mL, you receive 25mg CBN—above the 20mg threshold associated with reduced sleep disturbance

Indiana context: Between work stress, financial pressures, and health concerns, many Hoosiers suffer from poor sleep. Our formula addresses not just falling asleep but staying asleep through the night.

Anxiety and Stress

For Indiana professionals, students, and caregivers:

• Daytime functional relief: 0.3mL raw sublingual—CBD and CBG address anxiety without impairment. Perfect for managing workday stress in Indianapolis offices or during Purdue finals week.
• Nighttime: 1.0mL sublingual—full profile including CBN for sleep architecture

Evidence context: CBD anxiety research [3], CBG pharmacology [7][8], limonene entourage effects [20]

General Titration Principle for Indiana Residents

Start low, go slow. Indiana’s practical, safety-conscious culture aligns perfectly with this approach. Begin with 0.25-0.5mL sublingual and assess effects over 2-3 hours before increasing. Individual responses vary based on body weight, metabolism, tolerance, and concurrent medications. Hoosiers are known for being careful and methodical—apply that same approach here.

How Indiana Residents Can Access Our Products

Nationwide Shipping to Indiana

Since you’re outside our Houston delivery zone, we ship directly to your Indiana address via:

• USPS Priority Mail: 2-3 business days to anywhere in Indiana—Indianapolis, Fort Wayne, Evansville, South Bend, Carmel, Fishers, Bloomington, Hammond, Gary, Lafayette, Muncie, Terre Haute, Kokomo, and every small town in between
• FedEx/UPS Ground: 3-5 business days with tracking
• Discreet packaging: No cannabis branding visible—respecting Indiana’s more conservative community standards
• Temperature-stable packaging: Protects product integrity during hot Indiana summers
• Signature-required option: Available for security
• Full documentation included: COAs, receipts, and legal compliance paperwork

Shipping cost: Flat-rate shipping applies. International shipping documentation requirements don’t apply within the US, so your Indiana order ships smoothly.

Indiana-Specific Legal Documentation

Every shipment to Indiana includes:

• Certificate of Analysis (COA) confirming <0.3% delta-9 THC
• Hemp-derived product declaration
• Purchase receipt
• Farm Bill compliance statement

Your responsibility: Verify that hemp-derived cannabinoid products are permitted at your specific Indiana address. While the Farm Bill makes these products legal federally, we encourage Indiana customers to be informed about state and local regulations. We cannot assume legal responsibility for local ordinances, but we provide all documentation to support lawful possession.

No Medical Card Required

Unlike states with medical marijuana programs, Indiana residents don’t need to qualify for a specific condition list. If you’re 21 or older, you can order. This is especially important for Hoosiers who don’t qualify for Indiana’s limited medical CBD program (which only covers intractable epilepsy) but still need cannabinoid support.

Competitive Comparison: Why Indiana Residents Choose OilWell

OilWell vs. Generic Hemp CBD Products Available in Indiana

Many Indiana retailers sell hemp-derived CBD oils with minimal cannabinoid content:

For Indiana residents, this means you’re not getting a weak, single-compound product from a gas station or mall kiosk. You’re getting clinical-strength, multi-cannabinoid medicine that reflects the full potential of the cannabis plant.

OilWell vs. Traditional Illegal RSO

If you have access to traditional RSO through unofficial channels in Indiana, consider this comparison:

The choice for Indiana residents is clear: Why risk unregulated, possibly contaminated product when you can access a legal, tested, standardized formula that ships directly to your door?

The Science Behind Our Formula: Evidence for Indiana Readers

How We Evaluate Research

We prioritize evidence hierarchically: human clinical trials first, then systematic reviews, then institutional summaries (like NIH/NCCIH), then preclinical/mechanistic studies. This matters because the evidence base is uneven:

• CBD and delta-9 THC have the strongest human data
• Delta-8 THC, THCa, CBG, CBN, CBC rely more on reviews and animal studies
• Terpenes are promising but require conservative interpretation

What NIH Says About Cannabinoids

The National Center for Complementary and Integrative Health (NCCIH) identifies the strongest evidence for:

• Rare epilepsies (Epidiolex)
• Chemotherapy-related nausea/vomiting
• HIV/AIDS-related appetite loss

It notes only modest evidence for chronic pain and MS symptoms, with many other uses still early-stage [1]. This honest framing is what Indiana deserves—not overstated claims.

Cannabinoid-by-Cannabinoid Evidence

CBD (4,500mg in our formula):

• Best evidence: Seizure disorders (Epidiolex) [2]
• Anxiety: 2024 meta-analysis shows significant anxiolytic signal but limited clinical samples [3]
• Pain: 2024 review finds promising but heterogeneous evidence [4]
• Sleep: 2023 review notes methodologically weak studies [5]
• Safety: 2023 meta-analysis identifies liver enzyme elevation risk, especially with polypharmacy [6]
• Bottom line for Indiana: Most evidence-developed non-intoxicating cannabinoid, but strong evidence is condition-specific

CBG (3,000mg):

• Evidence: Mostly preclinical; human data sparse [7][8]
• Pharmacology: Precursor to other cannabinoids; interacts with CB receptors, alpha-2 adrenoceptors, 5-HT1A [7]
• Research areas: Neurologic disorders, inflammatory bowel disease, antibacterial activity [7][8]
• Caution: Commercially sold despite thin evidence [7]
• Bottom line for Indiana: Promising but not clinically validated; we’re transparent about this

Delta-8 THC (6,000mg):

• Evidence: Pharmacologically relevant but less characterized than delta-9 [9]-[11]
• Pharmacology: Partial CB1 agonist, less potent than delta-9 [9]
• Safety: 2023 review notes adverse event reports and quality concerns [10]
• Bottom line for Indiana: Real psychoactive effects, not “mild” or “safe by default”; we’re honest about this

THCa (1,500mg):

• Evidence: Low direct human data [12]
• Key point: Non-psychoactive unless heated; conversion to THC is customer-controlled [12]
• Research: Anti-inflammatory, neuroprotective, antineoplastic possibilities in preclinical studies [12]
• Bottom line for Indiana: This is your legal pathway to high-potency medicine at home

Delta-9 THC (90mg):

• Best evidence: Chemo nausea, HIV appetite, some pain/MS symptoms [1][13]
• Pain: 2022 review shows short-term benefit but increased dizziness, sedation, nausea [13]
• Mental health risk: 2025 review links high-concentration THC to psychosis and cannabis use disorder [15]
• Bottom line for Indiana: Lowest dose in our formula (90mg total) provides therapeutic contribution while minimizing risk; you control additional THC via decarboxylation

CBN (750mg):

• Evidence: Weak; marketing ahead of data [16][17]
• Sleep claim: 2021 review found no clinical trials using validated sleep measures [16]
• Bottom line for Indiana: Included at researched dosage levels (25-50mg per serving) but we don’t overstate claims

CBC (750mg):

• Evidence: Emerging, preclinical [18][19]
• Pharmacology: Distinct from other cannabinoids; antinociceptive, antibacterial, anti-seizure potential [18]
• Bottom line for Indiana: Scientifically credible minor cannabinoid deserving more research

Terpene Evidence: What Indiana Should Know

Terpene claims require even stricter interpretation than cannabinoids. Much literature comes from essential oils, non-cannabis plants, or preclinical models. The 2024 entourage-effect review confirms: terpene bioactivity is plausible, but robust human proof of cannabis-specific entourage effects remains limited [20][29].

Our seven terpenes:

• Limonene: Multifunctional monoterpene with antioxidant/anti-inflammatory potential [21]; oxidation products can be allergens [22]
• Myrcene: Anxiolytic, anti-inflammatory in preclinical; human evidence lacking [23]
• Caryophyllene: Selective CB2 agonist—most cannabinoid-relevant terpene [24]
• Pinene: Antioxidant, neuroprotective in preclinical; human trials lacking [25]
• Linalool: Stress/mood potential; oxidized forms are allergens [22][25][26]
• Humulene: Anti-inflammatory; rodent evidence of cannabimimetic properties [27]
• Terpinolene: Least clinically characterized; dominated by preclinical data [28]

Bottom line for Indiana: We include terpenes for potential synergy and because they make the experience more enjoyable, but we don’t claim they’re miracle compounds.

Practical Takeaways for Indiana Readers

1. CBD and delta-9 THC are the most evidence-developed actives in our formula
2. Delta-8 THC is psychoactive and not “mild”—use with appropriate caution
3. THCa changes with processing—your heating decision alters the product
4. CBG, CBN, CBC are promising but clinically immature
5. Terpene claims should be careful and conservative

We hold ourselves to the same standards we apply to the broader field. That’s what Indiana deserves.

Ordering from Indiana: Simple Steps

1. Visit our website: OilWellCBD.com
2. Select your product: RSO Sublingual Oil ($129.99) or RSO Vape Cartridge ($49.99)
3. Verify age: 21+ required
4. Enter Indiana shipping address: We ship to all Indiana counties
5. Choose shipping: USPS Priority (2-3 days) or FedEx/UPS Ground (3-5 days)
6. Receive your order: Discreet packaging, full COA documentation included
7. Consult your doctor: Especially important for Indiana patients with complex medical conditions

Phone support: (832) 416-2816
Email: [email protected]
Instagram: @oilwellcbd

Final Thoughts for Our Indiana Neighbors

We didn’t start this company in a boardroom. We started it when Bentley got up and walked. We built it through Colin’s personal battles with PTSD and benzo addiction. We earned trust through seven ABC13 features where we told the truth, even when it was uncomfortable.

Indiana values—hard work, honesty, community, and practical solutions—are our values too. Whether you’re a veteran in Terre Haute, a farmer in Decatur County, a teacher in Carmel, or a cancer patient in Indianapolis, you deserve the same level of transparency and quality that we’ve provided to Houston’s Texas Medical Center.

Our RSO isn’t traditional Rick Simpson Oil. It’s better—safer, more precise, legally compliant, and built on a decade of real-world formulation experience. Most importantly, it’s available to you right now, shipped directly to your Indiana home, with no medical card required and no legal gray areas.

We can’t promise miracles. We can promise this: If you give our RSO a fair shot, you’ll experience the most thoughtfully formulated, transparently produced, evidence-grounded cannabis medicine available in America today. And if you can’t afford it, we’ll give you the recipe to make your own.

That’s not marketing. That’s our promise to Indiana.

References

1. National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH. Accessed March 2026. Available at: https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
2. Talwar A, Estes E, Aparasu R, Reddy DS. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis. Exp Neurol. 2023;359:114238. PMID: 36206805.
3. Han K, Wang JY, Wang PY, Peng YC. Therapeutic potential of cannabidiol CBD in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. 2024;339:116049. PMID: 38924898.
4. Cásedas G, Yarza-Sancho M, López V. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in the treatment of pain. Pharmaceuticals Basel. 2024;17(11):1438. PMID: 39598350.
5. Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of cannabidiol in the management of insomnia: A systematic review. Cannabis Cannabinoid Res. 2023;8(2):213-229. PMID: 36149724.
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Rick Simpson Section References:

RS1. Simpson R. Phoenix Tears: The Rick Simpson Story. Simpson RamaDur LLC; 2012.

RS2. Laurette C, director. Run From The Cure: The Rick Simpson Story . 2005. Distributed via phoenixtears.ca and online platforms.

RS3. Simpson R. Instructions and dosing information published on phoenixtears.ca. Multiple dates. Accessed March 2026.

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RS5. Guzmán M, Duarte MJ, Blázquez C, et al. A pilot clinical study of delta-9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer. 2006;95(2):197-203. PMID: 16804518.

RS6. National Cancer Institute. Cannabis and Cannabinoids (PDQ) — Health Professional Version. NIH/NCI. Updated 2024. Available at: https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq

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