Rick Simpson Oil (RSO) in Mississippi River Wisconsin: The Complete Guide by OilWell Cannabis

If you’re standing on the banks of the Mississippi River in Wisconsin — whether you’re in Prairie du Chien, Cassville, or anywhere along those scenic bluffs — you’ve probably noticed the cannabis conversation has changed. Maybe you’ve heard a neighbor talk about RSO for chronic pain after a long day working the cranberry harvest. Maybe a friend in La Crosse mentioned using cannabis oil for sleep instead of reaching for another beer. Or maybe you’re a veteran in Onalaska who’s exhausted from cycling through prescription bottles that promised relief but delivered only side effects.

We get it. We’re OilWell Cannabis from Houston, Texas, and we’ve been where you are: watching the medical system fail people we love, searching for real alternatives, and sifting through a mountain of cannabis hype to find something that actually works. This guide is for every Wisconsinite along the Mississippi River who deserves honest answers about Rick Simpson Oil — what it is, what it isn’t, and why our modern, multi-cannabinoid RSO formula might be exactly what you’ve been looking for.

Who Was Rick Simpson? The Man Behind the Oil

Rick Simpson wasn’t a doctor. He wasn’t a scientist. He was a power engineer from Nova Scotia — a blue-collar tradesman who got hurt on the job in 1997, suffered a head injury that left him with brutal tinnitus and dizziness, and found himself trapped in a prescription cycle that made everything worse. When his doctor refused to consider cannabis, Simpson did what many folks in Wisconsin’s Driftless Region have done: he took matters into his own hands.

Simpson’s pivotal moment came in 2003, when he claimed three bumps on his arm were diagnosed as basal cell carcinoma. He applied concentrated cannabis oil, bandaged the spots, and according to his personal testimony, they disappeared in four days. No biopsy confirmation. No independent medical verification. Just a story that became the origin myth of RSO. It’s historically significant — it launched a global movement — but it’s not clinical evidence. And that’s the critical distinction we need to make right here, right now, for everyone reading this along the Mississippi River.

Here’s what Simpson got right: He brought cannabinoids into the spotlight when the world was ignoring them. He helped create the conditions for the legal cannabis industry we have today. The term “RSO” is now the most recognized name for full-spectrum cannabis extract because of his advocacy.

Here’s what he overstated: He claimed RSO could cure cancer and dozens of other diseases. He encouraged patients to use his oil instead of proven medical treatments. That advice has real harm potential — delayed cancer treatment can be fatal. We’re not here to sell you false hope. We’re here to give you the best possible version of the information so you can make an informed decision about what’s right for you and your family here in Wisconsin.

The Traditional RSO Protocol: 60 Grams Over 90 Days

Simpson’s treatment plan was specific: consume 60 grams of concentrated cannabis oil over roughly 90 days. For Wisconsinites who’ve heard about RSO through cancer support groups, veteran networks, or online forums, this is the protocol that gets passed around. We’re going to explain it fully because you deserve complete information — then we’re going to tell you why our modern formula requires a completely different approach.

The Titration Schedule

• Week 1: Start with a dose the size of half a grain of rice — about 10-15 mg of oil — three times daily (morning, afternoon, before bed). Total daily intake: 30-45 mg.
• Weeks 2-5: Double the dose every four days to build tolerance. By week five, you’re aiming for 1 gram per day (1,000 mg), split into three doses.
• Weeks 5-12: Maintain 1 gram per day until you’ve consumed the full 60 grams. That means roughly 333 mg per dose, three times daily.

Administration methods: Simpson recommended sublingual (under the tongue) for systemic issues like cancer, topical application for skin lesions, and acknowledged inhalation only for immediate symptom relief, not as primary treatment.

Important context: This protocol was designed around crude, unstandardized material. The THC content varied wildly depending on the starting plant material. At peak dosing, patients were consuming 600-900 mg of delta-9 THC daily — doses that have never been studied in controlled clinical settings and carry real risks: severe intoxication, anxiety, tachycardia, hypotension, and cannabis use disorder.

For those of you in Wisconsin’s river towns who might be considering this protocol, we need to be crystal clear: there are no published randomized controlled trials validating this 60-gram regimen for any condition. The doses Simpson recommended were based on personal experience, not pharmacokinetic modeling. Modern cannabinoid science shows us that less can be more — and that precise, multi-cannabinoid formulations often outperform single-compound dominance.

What Traditional RSO Actually Was: A Product Breakdown

Simpson’s oil was nearly black, thick as tar, with a strong cannabis and sometimes solvent-residual smell. It was made by soaking cannabis in naphtha or isopropyl alcohol, filtering, then evaporating the solvent in a rice cooker. This process had three fatal flaws:

1. Solvent risk: Naphtha contains benzene and other carcinogens. Isopropyl alcohol isn’t food-grade either. Without lab testing, you can’t verify complete solvent removal.
2. Terpene destruction: The high heat stripped away virtually all terpenes — the aromatic compounds that contribute to the entourage effect.
3. No standardization: Every batch was different. No lab testing. No cannabinoid quantification. No consistency.

If you’re in Wisconsin where we value precision and quality — from our cheese to our craft beer — this should raise red flags. You wouldn’t drink moonshine without knowing its proof. You shouldn’t consume cannabis oil without knowing its exact cannabinoid content.

OilWell’s Modern RSO Formula: A Multi-Cannabinoid Revolution

Our RSO is not traditional RSO. It’s a deliberate evolution. We respect what Rick Simpson started, but we’ve solved the problems that limited his original vision. For the Mississippi River communities that bridge the gap between Minnesota’s progressive cannabis policies and Illinois’s recreational market, our formula offers something unique: legal access to a clinical-strength, multi-cannabinoid product that you can use raw (non-psychoactive) or activate at home for full potency.

The Seven Cannabinoids: Why More is Better

Traditional RSO was THC-dominant. Our formula distributes 16,590 mg of total cannabinoids across seven distinct compounds:

• CBD: 4,500 mg — The most evidence-developed non-psychoactive cannabinoid, with research supporting epilepsy, anxiety, and pain contexts.
• CBG: 3,000 mg — The “mother cannabinoid” with promising preclinical research in neuroprotection and inflammation, though human trials are still emerging.
• Delta-8 THC: 6,000 mg — A psychoactive cannabinoid with antiemetic properties and pain-relieving potential, though less studied than delta-9.
• THCa: 1,500 mg — The acidic, non-psychoactive precursor to THC. Stays inactive unless you heat it, giving you complete control.
• Delta-9 THC: 90 mg — Intentionally kept low for Farm Bill compliance, but present for its documented benefits in nausea and pain.
• CBN: 750 mg — Marketed heavily for sleep, but the clinical evidence is weaker than the hype suggests. Included for its potential synergy.
• CBC: 750 mg — An emerging cannabinoid with anti-inflammatory and neurogenic potential, still in early research stages.

For Wisconsinites who value scientific precision, this isn’t guesswork. Every milligram is lab-verified. Every batch is consistent. You know exactly what you’re getting.

The Seven Terpenes: Restoring What Simpson Lost

Traditional RSO had no terpenes. Our formula includes live terpenes at 5% with a specific profile designed to complement the cannabinoids:

• Limonene: Citrus-bright, mood-lifting
• Myrcene: Earthy, potentially relaxing
• Caryophyllene: Pepper/spice, the only terpene known to directly activate CB2 receptors
• Pinene: Forest-fresh, may support mental clarity
• Linalool: Floral lavender notes, calming
• Humulene: Woody, anti-inflammatory potential
• Terpinolene: Complex piney-fruity aroma

If you’ve walked through Wisconsin’s pine forests after a rain, you’ve smelled pinene. If you’ve peeled an orange from a Florida grove shipped up the Mississippi, you’ve smelled limonene. These aren’t exotic chemicals — they’re nature’s building blocks, restored to cannabis medicine.

Our Story: How a Paralyzed Dog Named Bentley Changed Everything

OilWell Cannabis didn’t start in a boardroom. It started with a dog in Houston, but the story resonates across the Mississippi River in Wisconsin’s tight-knit communities where people would do anything for their pets.

Bentley was Colin Valencia’s companion — family. When veterinarians said euthanasia was the only humane option for his paralyzed back legs, Colin refused. A rescue worker named Jessica asked the question that changed everything: “You’ve moved how many tons of weed and you’ve never heard of CBD?”

Colin made a CBD golden paste. Bentley got up. He walked. He brought his ball to play. That wasn’t placebo — dogs don’t respond to placebo. That was cannabinoid medicine succeeding where pharmaceuticals failed.

Bentley lived ten more years, dying naturally at age twenty. During those years, Colin developed formulas for every age-related condition: neurodegeneration (CBG), dementia (CBC), glaucoma (THC), arthritis (multi-cannabinoid anti-inflammatory). Single cannabinoids weren’t enough. Bentley’s life depended on precise, multi-cannabinoid synergy.

Colin also knows pharmaceutical dependence personally. He quit Xanax cold turkey using the same cannabinoid knowledge he developed for Bentley. He created Peace Gummies during midnight benzo withdrawal experiments. He uses the vape form personally for PTSD and insomnia. This isn’t theoretical — it’s lived experience.

When we say we understand what you’re going through in Wisconsin, whether you’re a veteran in La Crosse, a cancer patient in Prairie du Chien, or a chronic pain sufferer in Cassville, we mean it. We’ve been there.

Farm Bill Compliance: Why Our RSO is Legal in Wisconsin

Wisconsin’s cannabis laws can feel like a patchwork quilt — medical program in Madison, CBD shops in Milwaukee, and confusion everywhere else. Here’s what matters for Mississippi River residents: our RSO is 100% Farm Bill compliant.

The 2018 Farm Bill legalized hemp-derived products containing less than 0.3% delta-9 THC. Our 30mL bottle contains only 90mg of delta-9 THC total — that’s 3mg per mL, well under the legal threshold.

But here’s the game-changer: THCa is not delta-9 THC. Our product contains 1,500mg of THCa in its raw, non-psychoactive form. You can purchase it legally in Wisconsin, possess it legally, and transport it legally.

Then, if you choose, you can decarboxylate it at home: heat the oil at 260°F for 45-60 minutes, and that 1,500mg of THCa converts to approximately 1,315mg of delta-9 THC. Combined with the existing 90mg, you get about 1,405mg of total delta-9 THC — giving you psychoactive potency comparable to traditional illegal RSO, entirely through legal means.

This isn’t a loophole. It’s chemistry. It’s patient-controlled potency. It’s the most significant innovation in legal cannabis access since the Farm Bill itself.

Important legal note: You are responsible for understanding Wisconsin law. THCa converts to THC when heated. Our products ship with full documentation, COAs, and receipts. We assume no legal responsibility for your decarboxylation choices.

Open-Source Formulas: Transparency You Won’t Find Anywhere Else

Rick Simpson gave his oil away for free. We can’t do that — we’re a business with lab testing, quality control, and employees to pay. But we can do the next best thing: publish the complete formula.

If you’re in Wisconsin and $129.99 for our sublingual oil isn’t in your budget, you can source the individual cannabinoid distillates and make it yourself. The recipe is right here in this document. No secrets. No proprietary blends. Just the exact milligrams and percentages.

We also published Bentley’s CBD golden paste recipe for pets — the same formula that got a paralyzed dog walking again. If your dog in Vernon County or your cat in Crawford County is suffering, you can make that too.

This isn’t marketing. It’s the foundation of who we are. Colin said it first in 2019 on ABC13: “I’m not trying to sell people snake oil. I’m not trying to sell people hope. But there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot.”

Two Formats for Wisconsin Lifestyles

We offer RSO in two formats because Mississippi River living is diverse. Some days you’re fishing the backwaters and need discreet relief. Other nights you’re dealing with breakthrough pain and need fast action.

RSO Sublingual Oil — $129.99

• 30mL bottle (1 fl oz)
• 16,590mg total cannabinoids (553mg per mL)
• Seven cannabinoids at exact ratios
• 5% live terpenes
• Organic MCT oil base
• Onset: 15-45 minutes
• Duration: 4-6 hours
• Bioavailability: 13-19%
• Approximately 40-60 doses per bottle

Perfect for: Sustained relief during a long day on the river, nighttime dosing for sleep, precise control over your daily cannabinoid regimen.

RSO Vape Cartridge — $49.99

• 1-gram cartridge
• 900mg+ total cannabinoids
• Six cannabinoids (THCa auto-decarbs at vaping temp)
• 5%+ live terpenes
• Onset: 1-2 minutes
• Duration: 2-4 hours
• Bioavailability: 10-35%
• 510-thread universal battery

Perfect for: Breakthrough pain during a hike in Wyalusing State Park, acute nausea from chemo, panic attacks that need immediate interruption.

When to Use Each Format: A Wisconsin User’s Guide

Condition-Specific Dosing Guidance for Wisconsin Residents

Critical: These are not medical prescriptions. Consult your healthcare provider, especially if you’re receiving treatment at UW Health, Gundersen Health System, or any Wisconsin oncology center.

Chemotherapy-Related Nausea

• Pre-chemo: 0.5-1.0mL sublingual 1 hour before treatment
• Breakthrough nausea: 2-3 vape puffs (1-2 minute onset)
• Post-chemo: 0.5mL sublingual every 6 hours
• Sleep: 1.0-2.0mL sublingual before bed (delivers 25-50mg CBN)

Chronic Pain (Arthritis, Fibromyalgia, Neuropathy)

• Daytime: 0.3-0.5mL raw sublingual (anti-inflammatory without impairment)
• Nighttime: 0.5-1.0mL decarbed sublingual (pain relief + sleep)
• Breakthrough: Vape as needed

Anxiety & PTSD

• Daytime functional: 0.3mL raw sublingual (CBD + CBG, no high)
• Nighttime: 1.0mL sublingual (full profile including CBN)

Sleep Disorders

• Before bed: 1.0-2.0mL sublingual
• At 2.0mL, you get 50mg CBN — the dosage level investigated in 2024 sleep research

General Titration Principle: Start low, go slow. Begin with 0.25-0.5mL and assess effects over 2-3 hours. Wisconsin weather changes fast, and so can your body’s response to cannabinoids.

Safety First: Who Should Use Caution

Wisconsin’s hardworking culture sometimes means pushing through pain. But with RSO, safety comes first:

• Do not operate vehicles or machinery while using psychoactive doses
• Consult your physician if you’re on medications — cannabis can interact with many drugs
• Avoid if pregnant or nursing — cannabinoids can affect fetal development
• Keep out of reach of children — our products taste like cannabis, but kids don’t know the difference
• Liver concerns: CBD can affect liver enzymes. If you have liver disease or drink heavily (Wisconsin’s tavern culture is real), talk to a doctor first
• Mental health: High-dose THC can trigger anxiety or paranoia. If you have a history of psychosis, avoid activating the THCa

How to Order in Mississippi River Wisconsin

Same-Day Delivery? Not Yet.

We’re based in Houston, but we ship nationwide to every Mississippi River address in Wisconsin — from the Iowa border to the Illinois line.

Shipping Options:

• USPS Priority Mail: 2-3 business days to most Wisconsin addresses
• FedEx/UPS Ground: 3-5 business days
• Discreet packaging: No cannabis branding visible
• Tracking: Provided for all orders

International Shipping: We ship worldwide. Wisconsin’s agricultural exports travel globally; our hemp-derived RSO can too. All packages include COAs and customs documentation.

Wisconsin-Specific Legal Note: Our products contain less than 0.3% delta-9 THC at sale, meeting Wisconsin’s hemp program requirements. THCa converts to THC when heated. You are responsible for understanding local ordinances in your specific Mississippi River county.

Why OilWell Beats Wisconsin’s Other Options

vs. Wisconsin Dispensaries (if available):

• No medical card required
• Ships directly to your Mississippi River address
• Seven cannabinoids vs. THC-only products
• Patient-controlled potency

vs. CBD Shops in La Crosse or Prairie du Chien:

• 16,590mg total cannabinoids vs. typical 1,000mg CBD products
• Psychoactive option available via THCa decarboxylation
• Six minor cannabinoids, not just CBD

vs. Black Market RSO:

• Solvent-free production
• Third-party lab tested (pesticides, heavy metals, microbes)
• Exact cannabinoid amounts, not guesses
• Legal to possess and ship

vs. Making Your Own:

• We published the formula — you can DIY if you want
• But our lab-tested, standardized product saves you the chemistry experiment risks

Frequently Asked Questions from Wisconsin Residents

Q: Is this legal in Wisconsin?
A: Yes. Our products meet the 2018 Farm Bill standard of less than 0.3% delta-9 THC. Wisconsin’s hemp program aligns with federal law.

Q: Will I fail a drug test?
A: If you use the raw form (no heat), THCa doesn’t trigger standard tests. If you decarboxylate or vape, you will test positive for THC. Many Wisconsin employers still test; know your workplace policy.

Q: Can I use this while taking prescription medications from MyChart?
A: Consult your prescribing physician. CBD can interact with blood thinners, seizure meds, and other drugs processed by the liver.

Q: How does Wisconsin’s winter cold affect the oil?
A: MCT oil can thicken in cold temps. Store at room temperature. If it crystallizes, warm the bottle in your hands or place it in warm water for a few minutes.

Q: Can I take this to a Packers game at Lambeau?
A: The vape cartridge is portable and discreet. However, Lambeau Field has security. Our products are legal, but venue policies vary. Use your judgment.

Q: What if I live in a small town like De Soto? Will you really ship there?
A: Yes. We’ve shipped to every corner of rural Wisconsin. The Mississippi River region is beautiful but remote. We make sure you have access.

Q: How does this compare to what I could get in Illinois recreational dispensaries?
A: Illinois products require travel and high taxes. Our RSO ships to your door, offers 7 cannabinoids vs. typically 1-2, and costs less per milligram of total cannabinoids.

The Bottom Line for Mississippi River Wisconsin

We can’t promise RSO will cure anything. No ethical company can. What we can promise is this:

• Complete transparency: Every ingredient, every milligram, published openly
• Legal compliance: Farm Bill compliant, ships to Wisconsin legally
• Evidence-based education: We tell you what the science actually says, not what we wish it said
• Quality you can trust: Solvent-free, lab-tested, standardized
• Patient control: You decide if you want psychoactive effects or not
• Real stories: This company exists because a dog named Bentley got up and walked when medicine said he wouldn’t

From the bluffs of Wyalusing to the bridges of Prairie du Chien, from the cranberry marshes of Warrens to the classrooms of UW-La Crosse, Wisconsinites deserve cannabis education that respects their intelligence. You don’t need hype. You need honest science. You need a product that works. You need options that fit your lifestyle on the Mississippi River.

We’re OilWell Cannabis. We’re not from Wisconsin, but we’re for Wisconsin. And we’re here when you’re ready.

Ready to try our RSO? Order now for delivery to Mississippi River Wisconsin

Want to make your own? View the complete open-source formula here

Questions? Call us at (832) 416-2816 or email [email protected]