Rick Simpson Oil (RSO) in Clarke County, Iowa: The Complete Guide by OilWell Cannabis
If you’re reading this from Osceola, Murray, Woodburn, or anywhere across Clarke County’s rolling farmland, you’re probably wondering whether Rick Simpson Oil is something that could actually help you or someone you love. Maybe you’ve heard the stories. Maybe you’re dealing with chronic pain from decades of physical work. Maybe you’re supporting a family member through cancer treatment at Methodist Hospital in Des Moines or searching for alternatives to prescription sleep meds that stopped working years ago. Maybe you’re a veteran near the Clarke County Fairgrounds who heard about RSO at the VFW and thought, “Is this real, or is this just another internet cure?”
We get it. We really do. At OilWell Cannabis, we started this company not in a boardroom, but in a moment of desperation when a dog we loved was facing euthanasia. That story—Bentley’s story—is the foundation of everything we make, including the RSO formulas we now ship to families in Clarke County and across Iowa. And yes, we’re based in Houston, Texas, but we built our business to serve people exactly like you: folks in small communities who’ve been let down by conventional medicine, who need honest information, and who deserve access to products that are actually what they claim to be.
This guide is different from anything else you’ll find online. We’re not going to sell you snake oil. We’re not going to promise you a cancer cure. What we are going to do is give you the complete, evidence-based truth about Rick Simpson Oil—what it actually is, what the science says, what’s legal in Iowa, how our modern formulas improve on the original, and most importantly, whether it might be right for your specific situation here in Clarke County.
What RSO Really Means for Clarke County Families
The Man Behind the Oil
Rick Simpson wasn’t a doctor. He was a power engineer from Nova Scotia—a regular working guy, not so different from the folks who keep Clarke County’s agricultural and manufacturing sectors running. In 1997, he suffered a serious head injury when scaffolding collapsed at a hospital where he was working. The conventional medications his doctors prescribed either didn’t help or made his post-concussion symptoms worse. When he discovered cannabis provided more relief than anything else, his own doctor refused to even discuss it as an option .
That experience of being dismissed by the medical system resonates deeply in rural Iowa. We’ve heard from people in Clarke County who’ve driven three hours to specialists in Des Moines only to be handed another prescription they don’t want and can’t afford. Simpson’s frustration led him down a path that would change cannabis culture forever.
The 2003 Skin Cancer Story
The pivotal moment came in 2003. Simpson noticed three bumps on his arm that his doctor diagnosed as basal cell carcinoma. Rather than pursuing conventional treatment, Simpson applied concentrated cannabis oil directly to the lesions, covered them with bandages, and waited. According to his personal testimony, the bumps disappeared within four days .
Here’s what we need to say clearly: No biopsy confirmation exists. No independent medical documentation has been published. No peer-reviewed study has verified this outcome. What Simpson described is personal testimony, not medical evidence. But it was historically significant—it became the origin story that launched a global movement.
For families in Clarke County dealing with a cancer diagnosis, we understand why this story matters. When you’re facing something terrifying, anecdotal hope can feel like a lifeline. But hope without honest information can be dangerous. That’s why we’re telling you the full story—not the edited version.
The 60-Gram Protocol That Still Circulates
Simpson’s core recommendation was a 90-day protocol designed to deliver 60 grams of concentrated oil. The titration schedule started with a dose the size of half a grain of rice three times daily, doubling the amount roughly every four days until reaching 1 gram per day by weeks five through twelve .
The math matters: Traditional RSO typically contained 60-90% delta-9 THC. At peak dosing, that meant approximately 600-900 milligrams of THC daily—far exceeding anything studied in controlled clinical settings. The FDA-approved synthetic THC drug dronabinol is typically dosed at just 2.5 to 20 milligrams per day [13].
What this means for Clarke County: If you’re researching RSO online, you’ll find this 60-gram protocol everywhere. But it was never validated in clinical trials. It relied on crude, unstandardized material. The solvent extraction method (using naphtha or isopropyl alcohol) created real contamination risks. And the delta-9 THC exposure at those doses carries documented risks including severe intoxication, anxiety, panic, tachycardia, and cannabis use disorder [1][13][14][5].
We respect what Simpson started, but we refuse to follow a protocol that science has never validated and that carries proven safety concerns.
How OilWell’s RSO Formulas Diverge—and Why That Matters for Iowa
OilWell’s RSO is not traditional Rick Simpson Oil. We’re transparent about this because honesty is the foundation of trust. Here’s how our modern, multi-cannabinoid approach specifically addresses the needs of Clarke County residents:
1. Multi-Cannabinoid Synergy Instead of THC Dominance
Traditional RSO was essentially just delta-9 THC—60-90% of total content. Our sublingual formula distributes 16,590 milligrams of total cannabinoids across seven distinct compounds:
- CBD (4,500mg): The most evidence-developed non-psychoactive cannabinoid, with established research in seizure disorders and emerging support for anxiety and pain management [1]-[4]
- CBG (3,000mg): A promising minor cannabinoid with neuroprotective and anti-inflammatory potential, though human trials remain limited [7][8]
- Delta-8 THC (6,000mg): A psychoactive THC analogue with documented antiemetic properties, though less potent than delta-9 [9]-[11]
- THCa (1,500mg): The acidic precursor that stays non-psychoactive until heated, offering anti-inflammatory benefits via COX-2 inhibition [12]
- Delta-9 THC (90mg): Present at just 3mg per mL—well under the 0.3% Farm Bill limit but enough for therapeutic contribution
- CBN (750mg): Positioned for sleep support, though we openly acknowledge the human evidence remains weak [16][17]
- CBC (750mg): An emerging cannabinoid with preclinical interest in neurogenesis and anti-inflammatory pathways [18][19]
Why this matters in Clarke County: If you’re a farmer near Osceola dealing with chronic back pain from decades of labor, a single cannabinoid won’t address the multi-faceted nature of your condition. Pain involves inflammation, nerve signaling, sleep disruption, and mood. Our seven-cannabinoid matrix works across multiple pathways simultaneously—something traditional RSO simply cannot do.
2. Preserved Terpenes—Not Destroyed by Heat
Traditional RSO’s solvent extraction and high-heat evaporation destroyed virtually all terpenes. Our formula includes live terpenes at 5% with a specific seven-terpene profile:
- Limonene (citrus-bright): Antioxidant and anti-inflammatory potential [21]
- Myrcene: Anxiolytic properties in preclinical models [23]
- Caryophyllene (pepper/spice): Direct CB2 receptor agonist with anti-inflammatory activity [24]
- Pinene (forest-fresh): Neuroprotective signals in early research [25]
- Linalool (lavender): Calming effects supported by preclinical studies [26]
- Humulene (earthy, woody): Anti-inflammatory potential via unique pathways [27]
- Terpinolene (piney, fruity): Complex bioactivity still being characterized [28]
The Clarke County connection: Many of you grew up around Iowa’s pine forests and farmland. You know the smell of fresh-cut lumber, of lavender from your grandmother’s garden, of citrus from the farmers market in Osceola. These aren’t just pleasant aromas—they’re compounds your body recognizes. We preserve them because the entourage effect [20][29] suggests cannabinoids and terpenes work better together, even though robust human proof remains limited.
3. Patient-Controlled Potency—You Decide, Not Us
This is perhaps our most important innovation for Iowa residents. Our sublingual oil contains 1,500mg of THCa in its raw, non-psychoactive form. You have three choices:
Option 1: Raw (No Heat)
Use the oil as-is. THCa stays non-psychoactive. You get anti-inflammatory benefits without any “high.” Perfect for daytime use, working on the farm, driving into Des Moines, or staying functional for family responsibilities.
Option 2: Fully Activated (Home Decarboxylation)
Heat the oil at 260°F for 45-60 minutes. This converts THCa into approximately 1,315mg of delta-9 THC. Combined with the existing 90mg delta-9 THC and 6,000mg delta-8 THC, you achieve full therapeutic potency comparable to traditional RSO—but legally, because you control the activation.
Option 3: Vape (Instant Activation)
Our 1-gram RSO Vape Cartridge automatically decarboxylates THCa at vaping temperature (400-450°F), delivering relief in 1-2 minutes for acute situations.
Why this matters: Iowa’s medical cannabis program (TCUP) requires a medical card, qualifying conditions, and only allows purchase at licensed dispensaries. Our hemp-derived formula requires no medical card, has no qualifying condition restrictions, and ships directly to your door in Clarke County. You maintain complete control over whether your medicine is psychoactive or not.
4. Solvent-Free Production and Verified Safety
Traditional RSO used naphtha—a petroleum-based solvent that may contain benzene, toluene, and other carcinogens. Even isopropyl alcohol, while cleaner, isn’t intended for internal consumption .
Our production uses no solvents. We blend purified cannabinoid distillates and isolates in a controlled environment. The carrier is organic MCT oil—food-grade and neutral-tasting.
Every batch undergoes third-party testing for:
- Cannabinoid potency (±2% accuracy via HPLC/UHPLC)
- Heavy metals (arsenic, cadmium, lead, mercury)
- 400+ pesticides (LC-MS/MS and GC-MS/MS)
- Residual solvents (FDA Class 3 limits <5,000 ppm)
- Microbial contaminants (E. coli, Salmonella, Aspergillus)
For Clarke County families who’ve seen what contaminated products can do—whether it’s tainted grain or unsafe supplements—this level of testing isn’t optional. It’s essential.
Farm Bill Compliance: What Clarke County Needs to Know
Let’s address the question we hear most from Iowa residents: “Is this actually legal?”
Short answer: Yes, under the 2018 Farm Bill and Iowa’s hemp laws.
Detailed answer for Clarke County:
Our RSO Sublingual Oil contains only 90mg of delta-9 THC in the entire 30mL bottle—3mg per mL. This is well under the 0.3% delta-9 THC threshold established by federal law. All cannabinoids are hemp-derived. The product is Farm Bill compliant at the point of sale and legal to ship to Clarke County, Iowa.
The THCa (1,500mg) is not delta-9 THC. It’s the legal precursor. You can legally purchase, possess, and transport our product throughout Clarke County and Iowa. The decision to convert THCa to THC through heating is yours, made in the privacy of your home.
Important legal notice: Iowa law permits hemp-derived products with less than 0.3% delta-9 THC. However, customers are responsible for verifying current local regulations. We provide full documentation, COAs, and receipts with every shipment. The product is void where prohibited by law.
Comparison to Iowa’s Medical Program (TCUP):
- TCUP: Requires medical card, qualifying conditions (cancer, PTSD, epilepsy, terminal illness), travel to dispensary in Des Moines or other cities, limited product selection
- OilWell RSO: Age 21+, no medical card, ships directly to your Clarke County address, 7-cannabinoid formula, patient-controlled potency
Condition-Specific Guidance for Clarke County Residents
Critical disclaimer: These usage contexts are informed by research cited in our GENERAL KNOWLEDGE section [1]-[29]. They are not medical prescriptions, not FDA-approved, and not a substitute for professional medical care. Consult your healthcare provider before use, especially if you have underlying conditions, take medications, are pregnant or nursing. Do not operate vehicles or machinery while under the influence. Individual results vary.
For Chemotherapy Support
We know many Clarke County residents travel to Methodist Hospital in Des Moines or Iowa City for cancer treatment. Our formula can be used as complementary support:
- Pre-chemo: 0.5-1.0mL sublingual oil 1 hour before treatment. Delta-8 THC has documented antiemetic properties [9], while delta-9 THC supports nausea reduction [1][13].
- Acute breakthrough nausea: 2-3 vape puffs for immediate relief (1-2 minute onset)
- Post-chemo: 0.5mL sublingual every 6 hours as needed
- Sleep during treatment: 1.0-2.0mL before bed delivers 25-50mg CBN for sleep architecture support [16][17]
Important: RSO is not a cancer cure. Do not delay or replace proven oncologic therapies. Our formula is designed to support quality of life during treatment, not to treat cancer itself.
For Chronic Pain (Agricultural & Manufacturing Workers)
Clarke County’s economy runs on agriculture and manufacturing. We’ve talked to folks who’ve spent decades working the land or on factory floors near Osceola. Chronic pain is a constant companion.
- Daytime functional relief: 0.3-0.5mL raw sublingual oil (non-psychoactive). Delivers CBD [4], CBG [7][8], and THCa [12] for multi-pathway anti-inflammatory action without impairment.
- Nighttime relief: 0.5-1.0mL decarboxylated sublingual oil. Combines activated THC [13] with CBN [16][17] for pain relief plus sleep support.
- Breakthrough pain: Vape as needed for rapid onset relief.
The beta-caryophyllene in our terpene profile [24] specifically activates CB2 receptors involved in inflammatory pain—relevant for arthritis, back pain, and repetitive strain injuries common in farming communities.
For Sleep Disorders
Sleep issues plague rural communities. Whether it’s worrying about crop prices, equipment breakdowns, or health problems, Clarke County residents often struggle with insomnia.
- Before bed: 1.0-2.0mL sublingual oil
- At 2.0mL, you receive 50mg CBN—the dosage level investigated in 2024 sleep literature [17]
- At 1.0mL, you receive 25mg CBN—above the 20mg threshold associated with reduced sleep disturbance [16]
Note: We are transparent that CBN’s sleep evidence is limited [16][17]. Many customers report benefits, but we don’t overstate what the science currently supports.
For Anxiety & PTSD
PTSD affects veterans throughout Clarke County and beyond. The VA clinic in Des Moines serves many who’ve returned from service struggling with trauma.
- Daytime functional relief: 0.3mL raw sublingual oil. CBD has documented anxiolytic effects [3], while CBG shows promise in early research [7][8].
- Nighttime: 1.0mL sublingual oil delivers full cannabinoid profile including CBN for sleep architecture.
- Acute anxiety episodes: Vape provides 1-2 minute onset relief.
The limonene in our terpene profile [20][21] may contribute to mood support through entourage effects.
How Clarke County Residents Can Order
Shipping to Iowa
While our same-day delivery system serves Houston’s Texas Medical Center and surrounding zones, we ship nationwide to Clarke County and all of Iowa.
Shipping details:
- All 50 states where Farm Bill-compliant products are legal (including Iowa)
- USPS Priority Mail: 2-3 business days to Clarke County addresses
- FedEx/UPS Ground: 3-5 business days
- Discreet packaging: No cannabis branding visible on exterior
- Tracking: Provided for all orders
- Temperature-stable packaging: Essential for Iowa’s hot summers and cold winters
- Signature-required option: Available for added security
How to order:
- Visit oilwellcbd.com
- Choose your product: RSO Sublingual Oil ($129.99) or RSO Vape Cartridge ($49.99)
- Enter your Clarke County address (Osceola, Murray, Woodburn, or rural routes)
- Complete age verification (21+ required)
- Receive your shipment with full documentation and COAs
International note: While this guide focuses on Clarke County, Iowa, we do ship internationally. Iowa residents with family abroad should know our THCa-legal framework allows shipments to many countries where hemp products are permitted. Contact us at (832) 416-2816 or [email protected] for international orders.
Safety and Quality: Why It Matters More in Rural Iowa
Clarke County doesn’t have a cannabis dispensary on every corner. When you order a product online, you’re trusting that what’s on the label matches what’s in the bottle. Too often, that’s not the case.
Our Testing Protocol
Every batch undergoes comprehensive third-party testing:
- Potency: HPLC/UHPLC analysis confirms each cannabinoid to ±2% accuracy
- Heavy metals: ICP-MS testing for arsenic, cadmium, lead, mercury (all below FDA limits)
- Pesticides: 400+ compound screening via LC-MS/MS and GC-MS/MS
- Residual solvents: Headspace GC verifies compliance with FDA Class 3 limits (<5,000 ppm)
- Microbial contaminants: Comprehensive screening including E. coli, Salmonella, Aspergillus
We provide Certificates of Analysis (COAs) with every order. For Clarke County residents who may not have local access to cannabis-literate healthcare providers, these documents allow you to share exact cannabinoid profiles with your doctor in Osceola or Des Moines.
No Solvents, No Compromise
Traditional RSO’s naphtha extraction introduced benzene, toluene, and other carcinogens . Our production uses no solvents. We blend purified cannabinoid distillates in organic MCT oil—a food-grade carrier that ensures safety and consistency.
Media Recognition: Why ABC13’s Coverage Matters to You in Clarke County
You might be thinking: “Why should I care that a Houston TV station featured you?” Here’s why: In an industry where anyone can make a website and claim anything, third-party validation from a major-market ABC affiliate (America’s 4th-largest city) is rare and meaningful.
Between 2019 and 2023, ABC13 Houston featured Colin Valencia and OilWell Cannabis in seven comprehensive segments covering:
- Texas CBD business growth (September 2019)
- Cannabis entrepreneurship and decriminalization (March 2021)
- Delta-8 THC investigation—where Colin’s honest “maybe you want to get high” quote became iconic (May 2021)
- COVID-19 vaccination community initiative—donating $35,000 in product (August 2021)
- Delta-8 ban crisis—proactively removing products and warning competitors (October 2021)
- Biden marijuana pardons—where Colin revealed his personal cannabis conviction history (October 2022)
- Texas marijuana law evolution (April 2023)
Five different reporters sought Colin out because ABC13 editorial staff recognized him as Houston’s most credible, quotable cannabis authority. That credibility translates to you in Clarke County. When five journalists over four years independently return to the same source, it means that source has earned trust through consistency, expertise, and integrity.
Competitive Comparison: Why OilWell Makes Sense for Iowa
OilWell RSO vs. Iowa’s Medical Cannabis Program (TCUP)
| Feature | Iowa TCUP Dispensaries | OilWell RSO |
|---|---|---|
| Cannabinoid profile | THC-only (approx. 420mg per 0.5g) | 7 cannabinoids: CBD, CBG, delta-8, THCa, delta-9, CBN, CBC |
| CBG content | 0mg | 3,000mg |
| CBN content | 0mg | 750mg |
| CBC content | 0mg | 750mg |
| Patient-controlled potency | No—always psychoactive | Yes—THCa non-psychoactive until you heat it |
| Access requirements | Medical card + qualifying condition | Age 21+ only |
| Qualifying conditions | Cancer, PTSD, epilepsy, terminal illness, etc. | None required |
| Delivery | Drive to Des Moines or other cities | Ships directly to your Clarke County address |
| Farm Bill compliant | No (state medical program) | Yes—less than 0.3% delta-9 THC |
OilWell RSO vs. National Hemp CBD Brands (e.g., Lazarus Naturals)
| Feature | Leading Hemp RSO (10mL, 1,000mg) | OilWell RSO (30mL, 16,590mg) |
|---|---|---|
| Total cannabinoids | 1,000mg | 16,590mg |
| CBD content | ~950mg | 4,500mg |
| CBG content | 15.5mg | 3,000mg |
| CBN content | 0.7mg | 750mg |
| Delta-8 THC | 0mg | 6,000mg |
| THCa (convertible) | Minimal | 1,500mg (converts to ~1,315mg delta-9 THC) |
| Psychoactive option | Not meaningful | Yes—via THCa decarboxylation |
| Value | ~$40-50 | $129.99 |
For Clarke County residents: The math is clear. Our 30mL bottle contains over 16 times the total cannabinoids of typical hemp RSO products. If you’re serious about exploring cannabinoid therapy, concentration matters. You’d need to purchase 16+ bottles of standard hemp RSO to match one bottle of OilWell’s formula.
The Open-Source Promise: Our Gift to Clarke County
We publish our complete formulas publicly. If you can’t afford $129.99, we want you to have the recipe. That’s not marketing—that’s our core philosophy inherited from Rick Simpson’s free-distribution ethos, refined through Colin’s journey from the McAllen borderlands to Houston’s medical center.
RSO Sublingual Oil Formula (The Complete Recipe)
| Cannabinoid | Amount (per 30mL bottle) |
|---|---|
| CBD | 4,500mg |
| CBG | 3,000mg |
| Delta-8 THC | 6,000mg |
| THCa | 1,500mg |
| Delta-9 THC | 90mg |
| CBN | 750mg |
| CBC | 750mg |
| Total | 16,590mg |
- Live terpenes: 5%
- Carrier: Organic MCT oil
- Active per mL: 553mg
RSO Vape Cartridge Formula (The Complete Recipe)
| Cannabinoid | Percentage (per 1g cartridge) |
|---|---|
| CBD | 30% |
| CBG | 20% |
| Delta-8 THC | 15% |
| THCa | 10% |
| CBN | 10% |
| CBC | 10% |
- Live terpenes: 5%+
- 510-thread universal battery compatible
What this means for Clarke County DIYers: If you have access to cannabinoid distillates and isolates (increasingly available online), you can replicate our formula. We don’t hide behind proprietary blends. We want you to have options.
Getting Started: Your First Order to Clarke County
Step-by-Step Guide
-
Decide your format:
- Sublingual oil for sustained relief (4-6 hours), precise dosing, and the ability to use raw or decarboxylated
- Vape cartridge for rapid relief (1-2 minute onset), portability, and acute breakthrough symptoms
-
Choose your activation pathway:
- Raw (non-psychoactive) for daytime functionality
- Decarboxylated (psychoactive) for maximum therapeutic potential
- Many customers use both—raw during the day, decarbed at night
-
Start low, go slow:
- Begin with 0.25-0.5mL sublingual oil
- Assess effects over 2-3 hours before increasing
- Your body weight, metabolism, and tolerance all factor in
-
Place your order:
- Visit oilwellcbd.com
- Call (832) 416-2816 if you have questions
- Email [email protected] for custom formulations
-
Track your shipment:
- You’ll receive tracking within 24 hours
- Packages arrive in 2-5 business days depending on carrier
- Discreet packaging protects your privacy
What to Expect
First-time effects: Many Clarke County customers report noticing subtle changes within the first few days. Chronic pain may show modest improvement. Sleep might become more restful. Anxiety may feel more manageable. The entourage effect builds over time—consistent use over 1-2 weeks typically reveals more pronounced benefits.
Titration journal: We recommend keeping a simple log of dose, time, and effects. This helps you find your optimal level and provides valuable information to share with your healthcare provider in Osceola or Des Moines.
Conclusion: Why OilWell Belongs in Clarke County
We didn’t start this company to get rich. We started it because Bentley got up and walked. Because Colin lived through PTSD and benzo withdrawal and found relief when nothing else worked. Because we’ve seen what honest cannabinoid education can do for people who’ve been failed by conventional options.
Clarke County deserves the same access to quality, transparent, research-informed cannabis products that Houston has. You deserve to know exactly what’s in your medicine. You deserve to control whether it’s psychoactive or not. You deserve lab-tested safety and open-source honesty.
The bottom line: Rick Simpson drew the world’s attention to concentrated cannabis oil at a time when no one was listening. He was right that cannabinoids matter. He was wrong that crude, untested, high-THC oil was the best or only way forward.
We’ve taken his vision, added a decade of formulation science born from keeping Bentley alive, layered in medical-grade precision from Colin’s Baylor College of Medicine work, and created something that honors the original spirit while protecting your safety.
Whether you’re in Osceola, Murray, Woodburn, or on a rural route outside Weldon, we’re here. We ship to Clarke County. We answer our phones. We publish our formulas. We tell you what we know, what we don’t know, and what the science actually says.
That’s the OilWell difference. And that’s why we’re reaching out to Clarke County, Iowa.
Complete References
Rick Simpson Section References
RS1. Simpson R. Phoenix Tears: The Rick Simpson Story. Simpson RamaDur LLC; 2012.
RS2. Laurette C, director. Run From The Cure: The Rick Simpson Story . 2005. Distributed via phoenixtears.ca and online platforms.
RS3. Simpson R. Instructions and dosing information published on phoenixtears.ca. Multiple dates. Accessed March 2026.
RS4. Velasco G, Sánchez C, Guzmán M. Towards the use of cannabinoids as antitumour agents. Nat Rev Cancer. 2012;12(6):436-444. PMID: 22555283.
RS5. Guzmán M, Duarte MJ, Blázquez C, et al. A pilot clinical study of delta-9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer. 2006;95(2):197-203. PMID: 16804518.
RS6. National Cancer Institute. Cannabis and Cannabinoids (PDQ) — Health Professional Version. NIH/NCI. Updated 2024. Available at: https://www.cancer.gov/about-cancer/treatment/cam/hp/cannabis-pdq
General Knowledge References
-
National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH. Accessed March 2026. Available at: https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
-
Talwar A, Estes E, Aparasu R, Reddy DS. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis. Exp Neurol. 2023;359:114238. PMID: 36206805.
-
Han K, Wang JY, Wang PY, Peng YC. Therapeutic potential of cannabidiol CBD in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. 2024;339:116049. PMID: 38924898.
-
Cásedas G, Yarza-Sancho M, López V. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in the treatment of pain. Pharmaceuticals Basel. 2024;17(11):1438. PMID: 39598350.
-
Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of cannabidiol in the management of insomnia: A systematic review. Cannabis Cannabinoid Res. 2023;8(2):213-229. PMID: 36149724.
-
Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023;293(6):724-752. PMID: 36912195.
-
Nachnani R, Raup-Konsavage WM, Vrana KE. The pharmacological case for cannabigerol. J Pharmacol Exp Ther. 2021;376(2):204-212. PMID: 33168643.
-
Li S, Li W, Malhi NK, Huang J, Li Q, Zhou Z, Wang R, Peng J, Yin T, Wang H. Cannabigerol CBG: A comprehensive review of its molecular mechanisms and therapeutic potential. Molecules. 2024;29(22):5471. PMID: 39598860.
-
Tagen M, Klumpers LE. Review of delta-8-tetrahydrocannabinol delta8 THC: Comparative pharmacology with delta9 THC. Br J Pharmacol. 2022;179(15):3915-3933. PMID: 35523678.
-
LoParco CR, Rossheim ME, Walters ST, Zhou Z, Olsson S, Sussman SY. Delta-8 tetrahydrocannabinol: A scoping review and commentary. Addiction. 2023;118(6):1011-1028. PMID: 36710464.
-
Abdel-Kader MS, Radwan MM, Metwaly AM, Eissa IH, Hazekamp A, ElSohly MA. Chemistry and pharmacology of Delta-8-Tetrahydrocannabinol. Molecules. 2024;29(6):1249. PMID: 38542886.
-
Moreno-Sanz G. Can You Pass the Acid Test? Critical review and novel therapeutic perspectives of delta9-Tetrahydrocannabinolic Acid A. Cannabis Cannabinoid Res. 2016;1(1):124-130. PMID: 28861488.
-
McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R. Cannabis-based products for chronic pain: A systematic review. Ann Intern Med. 2022;175(8):1143-1153. PMID: 35667066.
-
Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327-360. PMID: 12648025.
-
Rittiphairoj T, Leslie L, Oberste JP, Yim TW, Tung G, Bero L, Riggs P, Hutchison K, Samet J, Li T. High-concentration delta-9-tetrahydrocannabinol cannabis products and mental health outcomes: A systematic review. Ann Intern Med. 2025;178(10):1429-1440. PMID: 40854216.
-
Corroon J. Cannabinol and sleep: Separating fact from fiction. Cannabis Cannabinoid Res. 2021;6(5):366-371. PMID: 34468204.
-
Lavender I, Garden G, Grunstein RR, Yee BJ, Hoyos CM. Using cannabis and CBD to sleep: An updated review. Curr Psychiatry Rep. 2024;26(12):712-727. PMID: 39612156.
-
Sepulveda DE, Vrana KE, Kellogg JJ, Bisanz JE, Desai D, Graziane NM, Raup-Konsavage WM. The potential of cannabichromene as a therapeutic agent. J Pharmacol Exp Ther. 2024;391(2):206-213. PMID: 38777605.
-
Zagožen M, Čerenak A, Kreft S. Cannabigerol and cannabichromene in Cannabis sativa L. Acta Pharm. 2021;71(3):355-364. PMID: 36654096.
-
André R, Gomes AP, Pereira-Leite C, Marques-da-Costa A, Monteiro Rodrigues L, Sassano M, Rijo P, Costa MDC. The entourage effect in cannabis medicinal products: A comprehensive review. Pharmaceuticals Basel. 2024;17(11):1543. PMID: 39598452.
-
Anandakumar P, Kamaraj S, Vanitha MK. D-limonene: A multifunctional compound with potent therapeutic effects. J Food Biochem. 2021;45(1):e13566. PMID: 33289132.
-
Ogueta IA, Brared Christensson J, Giménez-Arnau E, Brans R, Wilkinson M, Stingeni L, Foti C, Aerts O, Svedman C, Gonçalo M, Giménez-Arnau A. Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing. Contact Dermatitis. 2022;87(1):1-12. PMID: 35122274.
-
Surendran S, Qassadi F, Surendran G, Lilley D, Heinrich M. Myrcene: What are the potential health benefits of this flavouring and aroma agent? Front Nutr. 2021;8:699666. PMID: 34350208.
-
Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Al Kaabi J, Ojha S. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of beta-caryophyllene, a dietary cannabinoid. Biomed Pharmacother. 2021;140:111639. PMID: 34091179.
-
Weston-Green K, Clunas H, Jimenez Naranjo C. A review of the potential use of pinene and linalool as terpene-based medicines for brain health: Discovering novel therapeutics in the flavours and fragrances of cannabis. Front Psychiatry. 2021;12:583211. PMID: 34512404.
-
Dos Santos ÉRQ, Maia JGS, Fontes-Júnior EA, do Socorro Ferraz Maia C. Linalool as a therapeutic and medicinal tool in depression treatment: A review. Curr Neuropharmacol. 2022;20(6):1073-1092. PMID: 34544345.
-
Dalavaye N, Nicholas M, Pillai M, Erridge S, Sodergren MH. The clinical translation of alpha-humulene: A scoping review. Planta Med. 2024;90(9):664-674. PMID: 38626911.
-
Menezes IO, Scherf JR, Martins AOBPB, Ramos AGB, Quintans JSS, Coutinho HDM, Ribeiro-Filho J, de Menezes IRA. Biological properties of terpinolene evidenced by in silico, in vitro and in vivo studies: A systematic review. Phytomedicine. 2021;93:153768. PMID: 34634744.
-
Russo EB. Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364. PMID: 21749363.
OilWell Cannabis Contact Information:
- Phone: (832) 416-2816
- Email: [email protected]
- Website: https://oilwellcbd.com/
- Instagram: @oilwellcbd
- Address: 810 Richmond Ave, Houston, TX 77006 (Montrose neighborhood)
Hours: Monday-Thursday 10AM-7PM, Friday-Saturday 10AM-10PM, Sunday 10AM-4PM (Central Time)
Shipping to Clarke County, Iowa and all 50 states where Farm Bill-compliant products are legal.
THCa Rick Simpson Oil
Full-Spectrum • In-House Extraction
THE OILWELL PASSION PROJECT: THCa RSO
Experience true full-spectrum relief. Our Rick Simpson Oil is meticulously crafted in-house to preserve the complete cannabinoid and terpene profile of the plant. Potent, pure, and profound.
- 🌿 Maximum Potency
- 🔬 Third-Party Lab Tested
- 🚀 Same-Day Delivery Available