Rick Simpson Oil (RSO) in Massac County, Illinois: The Complete Guide by OilWell Cannabis
If you live in Massac County — whether you’re tending crops near the Ohio River, working in Metropolis, or caring for family in Brookport — you already understand what it means to make do with what you have. Our corner of southern Illinois is beautiful, resilient, and community-driven, but let’s be honest: when it comes to specialized health options, we don’t always have the same access as folks in Chicago or St. Louis. The nearest dispensary might be an hour away in Paducah or Carbondale. Your doctor may not be comfortable discussing cannabis. And if you’re dealing with chronic pain from years of physical work, cancer treatment side effects, or the invisible wounds of military service, you need real information — not hype.
That’s why we’re here. We’re OilWell Cannabis, and this guide was built specifically for Massac County residents who deserve honest, science-based education about Rick Simpson Oil (RSO). We can’t be there in person at Massac Memorial Hospital or at the Superman Festival, but we can ship our professionally formulated, lab-tested RSO directly to your doorstep in Metropolis, Brookport, Joppa, or anywhere else in Massac County — legally, discreetly, and with full transparency.
Understanding Rick Simpson Oil: From Nova Scotia to Southern Illinois
Who Created RSO and Why It Matters Here
Rick Simpson was a power engineer from Nova Scotia — a tradesman, not a scientist — who started making concentrated cannabis oil after conventional medicine failed him. In 1997, he suffered a head injury from a scaffolding fall that left him with persistent tinnitus and dizziness. The medications his doctors prescribed either didn’t help or made things worse. When he asked his physician about cannabis, the doctor dismissed it. Sound familiar? That same scenario plays out in clinics across southern Illinois every week.
Simpson’s pivotal moment came in 2003 when he claimed that applying cannabis oil directly to skin lesions diagnosed as basal cell carcinoma made them disappear within four days. Important context: no independent medical verification, no biopsy confirmation, no peer-reviewed documentation exists for this claim. We share this story not as medical proof, but as the historical catalyst for a global movement — because that movement eventually reached Massac County through people searching online, sharing in Facebook groups, and looking for alternatives when traditional treatments fall short.
The Original 60-Gram Protocol: What Simpson Recommended
Simpson’s famous treatment plan involved consuming 60 grams of oil over roughly 90 days through a specific titration:
- Week 1: Half a grain of rice-sized dose (10-15mg) three times daily
- Weeks 2-5: Double the dose every four days until reaching 1 gram per day
- Weeks 5-12: Maintain 1 gram daily divided into three doses
- Administration: Primarily oral (sublingual or swallowed), occasionally topical for skin issues
- Tolerance: Simpson claimed patients would adjust to psychoactive effects within 3-4 weeks
At peak dosing, this protocol delivered approximately 600-900 mg of delta-9 THC per day — far exceeding anything studied in controlled clinical settings. For perspective, the FDA-approved synthetic THC drug dronabinol is typically dosed at just 2.5 to 20 mg daily.
Why Massac County residents need to know this: Many people searching for “RSO dosing” find Simpson’s protocol online and try to follow it without understanding the risks. Illinois may have legalized cannabis, but that doesn’t mean every product sold as “RSO” is safe or appropriate for this dosing schedule. The crude, unstandardized nature of traditional RSO means every batch was different — no lab testing, no contaminant screening, no consistency. If you’re in Massac County buying from an unverified source, you’re taking significant risks.
Traditional RSO: What It Actually Was
Traditional RSO was:
- Appearance: Nearly black, thick, tar-like oil
- Extraction: Used naphtha (petroleum-based solvent) or isopropyl alcohol — neither food-grade
- Cannabinoids: 60-90% delta-9 THC, fully decarboxylated, with minor cannabinoids at random ratios
- Terpenes: Effectively zero — destroyed by heat and solvent
- Testing: None. No COAs, no potency verification, no safety screening
- Standardization: None. Every batch differed based on starting material
Here in Massac County, where many folks pride themselves on DIY solutions and self-reliance, it’s tempting to think “I’ll just make it myself.” But consider the residual solvent risk: naphtha may contain benzene and other carcinogens. Without access to professional lab equipment like what we have at OilWell, you cannot verify that your final product is safe to consume. That’s not a DIY project — that’s a health hazard.
About OilWell Cannabis: A Different Kind of RSO Company
Our Story: From the Borderplex to the Illinois River Valley
OilWell Cannabis was founded by Colin Valencia in Houston, Texas — but our roots trace back to McAllen, right on the Texas-Mexico border. Colin grew up in one of the most economically challenged and dangerous regions along the border, where poverty and cartel violence shape daily life. By sixteen, he had to leave home. He lost friends to prison and violence. He knows what it means to struggle, to be let down by systems that should protect people, and to find unconventional solutions when conventional ones fail.
That experience drives everything we do at OilWell. It’s why we’re not just another cannabis company trying to cash in on the green rush. It’s why we publish our complete formulas for free. It’s why we refuse to overpromise. And it’s why we understand what Massac County residents face when they can’t find relief through traditional medicine.
Bentley: The Dog Who Started Everything
Our company’s origin isn’t a business plan — it’s a dog named Bentley. When Bentley became paralyzed and veterinarians recommended euthanasia, Colin refused to accept that outcome. A rescue worker named Jessica asked the question that changed everything: “You’ve moved how many tons of weed and you’ve never heard of CBD?”
Colin created a CBD golden paste for Bentley. The result? Bentley got up, walked over, and brought his ball to play. Dogs don’t respond to placebo. That moment proved cannabinoids could do what pharmaceuticals couldn’t.
Bentley lived another ten years, dying naturally at age twenty. During those years, Colin developed specialized formulas for every age-related condition Bentley faced: neurodegeneration (CBG neuroprotection, THCa PPARγ), dementia (CBC neurogenesis), glaucoma (THC CB1 agonism), crippling arthritis (multi-pathway anti-inflammatory using CBD, CBG, THCa, and beta-caryophyllene). Single cannabinoids weren’t enough. Bentley’s evolving conditions required multi-cannabinoid synergy — the foundation of our RSO formula.
Colin’s Personal Journey: PTSD, Benzo Addiction, and Recovery
Colin also knows pharmaceutical dependence personally. He struggled with severe PTSD and Xanax addiction. When he decided to break free, he quit cold turkey — a dangerous feat — using the cannabinoid knowledge he developed keeping Bentley alive. Our Peace Gummies formula was created during midnight experiments while fighting through benzo withdrawal. Colin personally uses our vape form for insomnia and severe PTSD.
This isn’t theoretical knowledge from a lab. This is lived experience. When we say our products work, we’re not citing marketing copy — we’re describing what kept Colin functional when nothing else would.
Why Massac County Residents Can Trust Our Formulas
Our RSO formula diverges from traditional RSO in five deliberate, evidence-motivated ways:
- Multi-cannabinoid approach — Seven defined cannabinoids at specific ratios, not just whatever a single strain provides
- Terpene preservation — Live terpenes at 5% with a defined seven-terpene profile, not destroyed by heat
- THCa as separate ingredient — 1,500 mg of THCa that you control, not automatically decarboxylated
- Reduced delta-9 dominance — Only 90 mg delta-9 THC total, versus 600-900 mg per day in Simpson’s protocol
- Product format innovation — Sublingual oil for sustained relief AND vape cartridge for breakthrough moments
Our Media Recognition: Verified by ABC13 Houston
Between 2019 and 2023, ABC13 (Houston’s number-one news source) featured Colin and OilWell in seven distinct news segments. Five different reporters sought us out across business, law, medicine, community health, and politics. No other Houston cannabis operator matches this frequency or breadth.
What this means for Massac County residents: When you’re researching RSO online from your home in Metropolis or Brookport, you can verify our credibility through independent, third-party journalism — not just our marketing materials.
Our foundational quote from September 2019 captures our philosophy: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.”
Community Action That Matters
In August 2021, we gave away 1,000 caviar pre-rolls (approximately $35,000 in product) to encourage COVID-19 vaccination. We coordinated with the City of Houston. No political agenda — just community health.
In October 2021, when Texas reclassified Delta-8 as Schedule I overnight, we proactively removed all Delta-8 products before enforcement and warned other operators who were unknowingly shipping what had become illegal narcotics. We absorbed a major revenue loss to act ethically.
These aren’t marketing stories. These are documented actions that show our character.
Farm Bill Compliance: Legal RSO for Illinois Residents
The Legal Framework That Protects You
The 2018 Farm Bill legalized hemp-derived products containing less than 0.3% delta-9 THC by dry weight. Our RSO Sublingual Oil contains only 90 mg of delta-9 THC in the entire 30 mL bottle (3 mg/mL) — well under the federal limit. All cannabinoids are hemp-derived.
This means our product is legal to purchase, possess, and ship to Massac County, Illinois without a medical card. You must be 21 or older. We include full documentation, Certificates of Analysis, and receipts with every order.
Patient-Controlled Potency: The THCa Advantage
Our formula contains 1,500 mg of THCa — the non-psychoactive precursor to THC. You decide whether to use it raw or activate it:
Option 1: Raw (Non-Psychoactive)
Use the oil as-is. THCa stays in its acidic form, providing potential anti-inflammatory benefits via COX-2 inhibition and neuroprotective effects via PPARγ agonism — with zero impairment. Perfect for daytime use when you’re operating equipment on your farm, driving into Paducah for errands, or working your shift at one of Massac County’s manufacturing facilities.
Option 2: Home Decarboxylation (Full Potency)
Heat the oil at 260°F for 45-60 minutes in an oven-safe glass container. This converts 1,500 mg THCa into approximately 1,315 mg delta-9 THC. Combined with the existing 90 mg delta-9 THC, you get approximately 1,405 mg total delta-9 THC — achieving psychoactive potency comparable to traditional illegal RSO, entirely legally because activation happens after purchase under your control.
Option 3: Vape (Instant Activation)
Our vape cartridge operates at 400-450°F, instantly converting THCa with each puff for 1-2 minute onset relief.
Important Legal Notice for Massac County Residents
THCa converts to delta-9 THC when heated. Illinois law aligns with the Farm Bill at the federal level, but you are responsible for understanding local ordinances. Do not operate vehicles or machinery while under the influence of psychoactive cannabinoids. Keep products out of reach of children. This product is not evaluated by the FDA and is not intended to diagnose, treat, cure, or prevent any disease.
Open-Source Formulas: Transparency You Can Verify
We publish our complete formulas publicly — every cannabinoid, every milligram, every percentage. If you can’t afford our products, you can source the ingredients and make your own. This is our commitment to accessibility, especially important in economically challenged areas like parts of Massac County.
RSO Sublingual Oil Formula
| Cannabinoid | Amount |
|---|---|
| CBD | 4,500 mg |
| CBG | 3,000 mg |
| Delta-8 THC | 6,000 mg |
| THCa | 1,500 mg |
| Delta-9 THC | 90 mg |
| CBN | 750 mg |
| CBC | 750 mg |
| Total Cannabinoids | 16,590 mg |
- Live Terpenes: 5% (limonene, myrcene, caryophyllene, pinene, linalool, humulene, terpinolene)
- Format: 30 mL bottle with graduated dropper (0.1 mL increments)
- Active per mL: 553 mg cannabinoids
- Price: $129.99
RSO Vape Cartridge Formula
| Cannabinoid | Percentage |
|---|---|
| CBD | 30% |
| CBG | 20% |
| Delta-8 THC | 15% |
| THCa | 10% |
| CBN | 10% |
| CBC | 10% |
- Live Terpenes: 5%+
- Format: 1 Gram cartridge (510-thread universal battery)
- Price: $49.99
Terpene Profile: The “Entourage Effect”
Both products contain the same seven live terpenes for their potential synergistic benefits:
- Limonene (citrus-bright) – potential mood elevation
- Myrcene – relaxation properties
- Caryophyllene (β-caryophyllene) – unique CB2 receptor agonist, anti-inflammatory
- Pinene (forest-fresh) – potential cognitive clarity
- Linalool (floral, lavender) – calming effects
- Humulene (earthy, woody) – potential anti-inflammatory
- Terpinolene (piney, fruity) – complex aroma profile
Important context for Massac County readers: While the “entourage effect” is a compelling hypothesis, robust human clinical proof remains limited. We include terpenes because the preclinical science is promising, not because it’s proven. This is the kind of honest education that separates us from hype-driven brands.
When to Use Each Format: Practical Guidance for Massac County Life
| Your Situation | Recommended Format | Why It Works |
|---|---|---|
| Acute pain flare-up during harvest season | Vape | 1-2 minute onset for immediate relief |
| Chronic arthritis from years of physical work | Sublingual | 4-6 hour sustained relief |
| Daytime use – need to operate tractor/vehicle | Sublingual (raw) | Zero impairment, non-psychoactive |
| Nighttime use – struggling with sleep | Sublingual (decarbed) or Vape | CBN supports sleep architecture, THC aids relaxation |
| Breakthrough nausea from chemo | Vape | Fastest relief when you need it most |
| Precise dosing for careful titration | Sublingual | Graduated dropper allows 0.1 mL accuracy |
| Portability for trips to Paducah or Evansville | Vape | Discreet, compact, no measuring |
Condition-Specific Usage Context for Massac County Residents
Critical Disclaimer: These contexts are informed by research cited in our General Knowledge section. They are not medical prescriptions. Always consult your healthcare provider at Massac Memorial Hospital, your primary care physician, or a specialist in Paducah before using cannabinoid products. Do not discontinue prescribed treatments without medical supervision.
Chronic Pain from Physical Labor
Many Massac County residents work in agriculture, manufacturing, or construction — jobs that take a toll on the body over decades.
Our recommendation:
- Daytime: 0.3-0.5 mL raw sublingual oil for anti-inflammatory support without impairment
- Nighttime: 0.5-1.0 mL decarboxylated sublingual oil for full cannabinoid relief plus CBN for sleep
- Breakthrough: Vape as needed for acute pain spikes
Evidence: CBD shows promise for pain management [4]. Delta-9 THC demonstrates analgesic effects [13]. Beta-caryophyllene’s CB2 activation offers anti-inflammatory pathways [24]. THCa inhibits COX-2 enzymes [12]. This multi-pathway approach targets pain through different mechanisms simultaneously — something single-cannabinoid products cannot match.
Cancer Supportive Care
For patients traveling to oncology centers in Paducah, Evansville, or Carbondale:
Our recommendation:
- Pre-chemo: 0.5-1.0 mL sublingual 1 hour before treatment
- Acute nausea: 2-3 vape puffs for immediate relief
- Post-treatment: 0.5 mL sublingual every 6 hours as needed
- Sleep: 1.0-2.0 mL sublingual before bed (delivers 25-50 mg CBN)
Evidence: Delta-8 THC demonstrates antiemetic properties [9]. Delta-9 THC is well-established for chemo-induced nausea [1][13]. CBD may buffer anxiety [3]. Many Massac County cancer patients face long drives for treatment — having reliable symptom management at home is crucial.
Sleep Disorders
Sleep issues plague many in our region, whether from chronic pain, PTSD, or the stress of economic uncertainty.
Our recommendation:
- Before bed: 1.0-2.0 mL sublingual oil
- At 2.0 mL, you receive 50 mg CBN — the dosage level investigated in 2024 sleep research
- At 1.0 mL, you receive 25 mg CBN — above the 20 mg threshold associated with reduced sleep disturbance
Evidence: CBN sleep literature is emerging but not yet definitive [16][17]. However, the combination of CBN with other cannabinoids and linalool terpene may support sleep architecture. Our formula is designed based on the best available research, not marketing hype.
PTSD and Anxiety
Massac County has significant veteran and first responder populations. The trauma from military service, workplace accidents, or personal crises doesn’t just go away.
Colin’s personal testimony: “I struggled with severe PTSD and Xanax addiction. The Peace Gummies formula I created during benzo withdrawal saved my life. I personally use our vape form for insomnia and severe PTSD.”
Our recommendation:
- Daytime functional relief: 0.3 mL raw sublingual (CBD + CBG address anxiety pathways without impairment)
- Nighttime: 1.0 mL sublingual for full cannabinoid profile with CBN
- Acute episodes: Vape for rapid onset relief
Evidence: CBD shows anxiolytic effects in systematic reviews [3]. CBG pharmacology suggests potential benefits [7][8]. Limonene may contribute to mood elevation [20][21].
Delivery to Massac County: How You Get Our Products
Nationwide Shipping to Illinois
We ship directly to Massac County via USPS Priority Mail (2-3 business days), FedEx Ground, or UPS Ground (3-5 business days). All packaging is discreet with no cannabis branding visible. You’ll receive tracking information for every order.
Temperature-Stable Packaging
Southern Illinois summers can be brutal. Our temperature-stable packaging ensures product integrity during shipping, even when the mercury hits 95°F in Metropolis in July.
Signature-Required Option Available
If you’re concerned about package security in rural areas or want to ensure personal receipt, we offer signature-required delivery.
How Our Formulas Connect to Real Science
Every cannabinoid and terpene in our formula has its own evidence profile in our General Knowledge section — 29 peer-reviewed citations from journals like Annals of Internal Medicine, British Journal of Pharmacology, and Journal of Pharmacology and Experimental Therapeutics. We don’t cherry-pick studies. We present the full picture:
- What’s well-supported by human clinical data
- What’s emerging from preclinical research
- What’s overstated relative to current evidence
For Massac County readers navigating cancer treatment, chronic pain, or mental health challenges, this honest framing is essential. You deserve to make informed decisions based on real science, not false promises.
Research Limits We Acknowledge
- Evidence is highly uneven — CBD and delta-9 THC have the strongest human data; other compounds rely more on reviews and animal studies
- Data categories aren’t interchangeable — whole-plant extract findings don’t apply to purified molecules
- Minor cannabinoids are commercially interesting because they’re underexplored — which means claims often outrun evidence
- Product quality matters as much as molecule identity — labeling inaccuracies, contamination, and dose variability affect real-world results
- THCa chemistry changes with storage and heating — converting to THC whether you intend it or not
Common Overstatements We Avoid
- ❌ “CBN is a proven sleep aid”
✅ “CBN shows promise for sleep but human evidence remains limited” - ❌ “Myrcene reliably causes sedation”
✅ “Myrcene has preclinical bioactivity but direct human proof is lacking” - ❌ “Terpenes have proven entourage effects”
✅ “Entourage hypotheses are compelling but robust clinical proof remains limited” - ❌ “THCa is always non-psychoactive”
✅ “THCa itself isn’t psychoactive but converts to THC with heat” - ❌ “Delta-8 THC is safe because it’s hemp-derived”
✅ “Delta-8 is psychoactive with less safety characterization than delta-9”
Competitive Comparison: Why OilWell Stands Out
vs. Dispensary RSO (if you drive to Paducah or Carbondale)
| Dimension | Typical Dispensary RSO | OilWell RSO |
|---|---|---|
| Cannabinoids | Primarily THC only | 7 cannabinoids: CBD, CBG, delta-8 THC, THCa, delta-9 THC, CBN, CBC |
| CBG content | Minimal or none | 3,000 mg |
| CBN content | Minimal or none | 750 mg |
| Psychoactive control | Always psychoactive | You decide: raw or activated |
| Access requirements | Medical card (if medical dispensary) or 21+ (if recreational) | Age 21+, no medical card needed |
| Delivery | Must drive 60-90 minutes | Ships to your Massac County door |
vs. Hemp CBD RSO (online competitors)
| Dimension | Typical Hemp RSO | OilWell RSO |
|---|---|---|
| Total cannabinoids | ~1,000 mg | 16,590 mg |
| CBD content | ~950 mg | 4,500 mg |
| CBG content | Trace | 3,000 mg |
| Delta-8 THC | None | 6,000 mg |
| Psychoactive option | No meaningful effect | Yes, via THCa activation |
| Price | $40-50 | $129.99 |
The Math: Our bottle contains 16.5x more total cannabinoids at 2.6x the price — far better value per milligram of active compound.
For Massac County DIYers: The Golden Paste Recipe That Saved Bentley
We believe in accessibility. If you can’t afford our products right now, here’s the exact CBD golden paste recipe that saved Bentley’s life. Make it yourself. Help your pet. Share it with neighbors in Metropolis or Brookport who need help.
Ingredients:
- 1/2 cup organic turmeric powder
- 1 cup water
- 1/3 cup unrefined organic coconut oil
- 1-2 teaspoons freshly ground black pepper (critical for absorption)
- CBD oil (dosage based on pet size; consult your vet)
Instructions:
- Mix turmeric and water in saucepan, stir over low heat until thick paste forms (7-10 minutes)
- Add coconut oil and black pepper, mix thoroughly
- Cool and store in refrigerator up to 2 weeks
- Mix in CBD oil before serving
- Serve with food once or twice daily, monitor your pet, consult your vet
This recipe is free. It always will be. That’s our version of Rick Simpson’s free-distribution ethos.
Safety and Legal Compliance for Illinois
Illinois State Law
Illinois legalized recreational cannabis in 2020. Adults 21+ can possess up to 30 grams of cannabis flower. Hemp-derived products like ours are explicitly legal under both federal Farm Bill and Illinois state law.
Drug Testing Warning
If you’re subject to workplace drug testing in Massac County (manufacturing, transportation, healthcare jobs), understand that:
- Raw THCa may not trigger standard THC tests
- Decarboxylated THCa WILL convert to THC and trigger positive results
- Delta-8 THC will trigger positive results
- Our vape cartridge will trigger positive results
We are honest about this because your livelihood matters. If your job requires testing, use the raw form only or discuss with your employer.
Age Requirement
21+ only. We verify age on all orders.
Massac County Resources and Next Steps
Healthcare Provider Consultation
We encourage Massac County residents to discuss cannabinoid use with:
- Your primary care physician
- Specialists at Massac Memorial Hospital
- Cancer centers in Paducah (KY) or Evansville (IN)
- Pain management clinics in Carbondale (IL)
Bring our Certificate of Analysis to your appointment. Show them the formula. Make informed decisions together.
Veteran Support
Massac County has significant veteran populations. If you’re struggling with PTSD, chronic pain, or transitioning off pharmaceuticals:
- Our formula was developed by someone who lived it
- The VA system is increasingly recognizing cannabinoid therapy
- We ship discreetly to your Massac County address
Senior Citizens
For Massac County seniors dealing with arthritis, sleep issues, or age-related health challenges:
- Start with raw sublingual oil (non-psychoactive)
- Gradual titration is key
- Our graduated dropper allows precise dosing
- No need to drive long distances — we ship to you
How to Order: Simple Process for Massac County
- Visit our website: oilwellcbd.com/thca-rick-simpson-oil-rso-by-oilwell-cannabis-of-houston-texas/
- Select your product: Sublingual Oil ($129.99) or Vape Cartridge ($49.99)
- Verify age: 21+ required
- Choose shipping: USPS Priority (2-3 days) or FedEx/UPS Ground (3-5 days)
- Track your order: Email confirmation with tracking
- Receive at your Massac County address: Discreet packaging, temperature-stable
Questions? Call (832) 416-2816 or email [email protected]
Final Thoughts for Massac County
We know Massac County because we understand communities like it. We come from the borderlands of Texas where resources are scarce and resilience is necessary. We built OilWell on the same values you live by: honesty, hard work, community support, and refusing to give up when someone you love is suffering.
When Bentley got up and brought his ball to Colin, that wasn’t just a dog recovering. That was proof that cannabinoids can do things pharmaceuticals cannot. When Colin used that same knowledge to quit Xanax cold turkey, that wasn’t just personal recovery. That was proof the formula works for severe PTSD and addiction.
For Massac County residents facing cancer, chronic pain, sleep disorders, or PTSD, we offer:
- Legal, Farm Bill-compliant access without driving to a dispensary
- A seven-cannabinoid, seven-terpene formula backed by peer-reviewed research
- Patient-controlled potency (non-psychoactive or full-strength, you choose)
- Third-party lab testing with COAs available
- Open-source formulas if you need to make your own
- Honest education that refuses to overstate what the science actually shows
- Direct shipping to Metropolis, Brookport, Joppa, and all Massac County communities
We don’t have a storefront in Massac County. But we’re here for you. We’re the company that saved a paralyzed dog, helped our founder quit benzos, and gives away formulas for free because we believe health information should be accessible to everyone — whether you’re in Houston, Chicago, or right here along the Ohio River in southern Illinois.
Order today. Ask questions. Read the science. Make your own if you need to. We’re OilWell Cannabis, and we’re here to help Massac County residents find their own path to relief.
Complete Reference List
-
National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH. Accessed March 2026. Available at: https://www.nccih.nih.gov/health/cannabis-marijuana-and-cannabinoids-what-you-need-to-know
-
Talwar A, Estes E, Aparasu R, Reddy DS. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy indications: A systematic review and meta-analysis. Exp Neurol. 2023;359:114238. PMID: 36206805.
-
Han K, Wang JY, Wang PY, Peng YC. Therapeutic potential of cannabidiol CBD in anxiety disorders: A systematic review and meta-analysis. Psychiatry Res. 2024;339:116049. PMID: 38924898.
-
Cásedas G, Yarza-Sancho M, López V. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in the treatment of pain. Pharmaceuticals Basel. 2024;17(11):1438. PMID: 39598350.
-
Ranum RM, Whipple MO, Croghan I, Bauer B, Toussaint LL, Vincent A. Use of cannabidiol in the management of insomnia: A systematic review. Cannabis Cannabinoid Res. 2023;8(2):213-229. PMID: 36149724.
-
Lo LA, Christiansen A, Eadie L, Strickland JC, Kim DD, Boivin M, Barr AM, MacCallum CA. Cannabidiol-associated hepatotoxicity: A systematic review and meta-analysis. J Intern Med. 2023;293(6):724-752. PMID: 36912195.
-
Nachnani R, Raup-Konsavage WM, Vrana KE. The pharmacological case for cannabigerol. J Pharmacol Exp Ther. 2021;376(2):204-212. PMID: 33168643.
-
Li S, Li W, Malhi NK, Huang J, Li Q, Zhou Z, Wang R, Peng J, Yin T, Wang H. Cannabigerol CBG: A comprehensive review of its molecular mechanisms and therapeutic potential. Molecules. 2024;29(22):5471. PMID: 39598860.
-
Tagen M, Klumpers LE. Review of delta-8-tetrahydrocannabinol delta8 THC: Comparative pharmacology with delta9 THC. Br J Pharmacol. 2022;179(15):3915-3933. PMID: 35523678.
-
LoParco CR, Rossheim ME, Walters ST, Zhou Z, Olsson S, Sussman SY. Delta-8 tetrahydrocannabinol: A scoping review and commentary. Addiction. 2023;118(6):1011-1028. PMID: 36710464.
-
Abdel-Kader MS, Radwan MM, Metwaly AM, Eissa IH, Hazekamp A, ElSohly MA. Chemistry and pharmacology of Delta-8-Tetrahydrocannabinol. Molecules. 2024;29(6):1249. PMID: 38542886.
-
Moreno-Sanz G. Can You Pass the Acid Test? Critical review and novel therapeutic perspectives of delta9-Tetrahydrocannabinolic Acid A. Cannabis Cannabinoid Res. 2016;1(1):124-130. PMID: 28861488.
-
McDonagh MS, Morasco BJ, Wagner J, Ahmed AY, Fu R, Kansagara D, Chou R. Cannabis-based products for chronic pain: A systematic review. Ann Intern Med. 2022;175(8):1143-1153. PMID: 35667066.
-
Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003;42(4):327-360. PMID: 12648025.
-
Rittiphairoj T, Leslie L, Oberste JP, Yim TW, Tung G, Bero L, Riggs P, Hutchison K, Samet J, Li T. High-concentration delta-9-tetrahydrocannabinol cannabis products and mental health outcomes: A systematic review. Ann Intern Med. 2025;178(10):1429-1440. PMID: 40854216.
-
Corroon J. Cannabinol and sleep: Separating fact from fiction. Cannabis Cannabinoid Res. 2021;6(5):366-371. PMID: 34468204.
-
Lavender I, Garden G, Grunstein RR, Yee BJ, Hoyos CM. Using cannabis and CBD to sleep: An updated review. Curr Psychiatry Rep. 2024;26(12):712-727. PMID: 39612156.
-
Sepulveda DE, Vrana KE, Kellogg JJ, Bisanz JE, Desai D, Graziane NM, Raup-Konsavage WM. The potential of cannabichromene as a therapeutic agent. J Pharmacol Exp Ther. 2024;391(2):206-213. PMID: 38777605.
-
Zagožen M, Čerenak A, Kreft S. Cannabigerol and cannabichromene in Cannabis sativa L. Acta Pharm. 2021;71(3):355-364. PMID: 36654096.
-
André R, Gomes AP, Pereira-Leite C, Marques-da-Costa A, Monteiro Rodrigues L, Sassano M, Rijo P, Costa MDC. The entourage effect in cannabis medicinal products: A comprehensive review. Pharmaceuticals Basel. 2024;17(11):1543. PMID: 39598452.
-
Anandakumar P, Kamaraj S, Vanitha MK. D-limonene: A multifunctional compound with potent therapeutic effects. J Food Biochem. 2021;45(1):e13566. PMID: 33289132.
-
Ogueta IA, Brared Christensson J, Giménez-Arnau E, Brans R, Wilkinson M, Stingeni L, Foti C, Aerts O, Svedman C, Gonçalo M, Giménez-Arnau A. Limonene and linalool hydroperoxides review: Pros and cons for routine patch testing. Contact Dermatitis. 2022;87(1):1-12. PMID: 35122274.
-
Surendran S, Qassadi F, Surendran G, Lilley D, Heinrich M. Myrcene: What are the potential health benefits of this flavouring and aroma agent? Front Nutr. 2021;8:699666. PMID: 34350208.
-
Hashiesh HM, Sharma C, Goyal SN, Sadek B, Jha NK, Al Kaabi J, Ojha S. A focused review on CB2 receptor-selective pharmacological properties and therapeutic potential of beta-caryophyllene, a dietary cannabinoid. Biomed Pharmacother. 2021;140:111639. PMID: 34091179.
-
Weston-Green K, Clunas H, Jimenez Naranjo C. A review of the potential use of pinene and linalool as terpene-based medicines for brain health: Discovering novel therapeutics in the flavours and fragrances of cannabis. Front Psychiatry. 2021;12:583211. PMID: 34512404.
-
Dos Santos ÉRQ, Maia JGS, Fontes-Júnior EA, do Socorro Ferraz Maia C. Linalool as a therapeutic and medicinal tool in depression treatment: A review. Curr Neuropharmacol. 2022;20(6):1073-1092. PMID: 34544345.
-
Dalavaye N, Nicholas M, Pillai M, Erridge S, Sodergren MH. The clinical translation of alpha-humulene: A scoping review. Planta Med. 2024;90(9):664-674. PMID: 38626911.
-
Menezes IO, Scherf JR, Martins AOBPB, Ramos AGB, Quintans JSS, Coutinho HDM, Ribeiro-Filho J, de Menezes IRA. Biological properties of terpinolene evidenced by in silico, in vitro and in vivo studies: A systematic review. Phytomedicine. 2021;93:153768. PMID: 34634744.
-
Russo EB. Taming THC: Potential cannabis synergy and phytocannabinoid-terpenoid entourage effects. Br J Pharmacol. 2011;163(7):1344-1364. PMID: 21749363.
RS1. Simpson R. Phoenix Tears: The Rick Simpson Story. Simpson RamaDur LLC; 2012.
RS2. Laurette C, director. Run From The Cure: The Rick Simpson Story . 2005.
RS3. Simpson R. Instructions and dosing information published on phoenixtears.ca.
RS4. Velasco G, Sánchez C, Guzmán M. Towards the use of cannabinoids as antitumour agents. Nat Rev Cancer. 2012;12(6):436-444. PMID: 22555283.
RS5. Guzmán M, Duarte MJ, Blázquez C, et al. A pilot clinical study of delta-9-tetrahydrocannabinol in patients with recurrent glioblastoma multiforme. Br J Cancer. 2006;95(2):197-203. PMID: 16804518.
RS6. National Cancer Institute. Cannabis and Cannabinoids (PDQ) — Health Professional Version. NIH/NCI. Updated 2024.
OilWell Cannabis
810 Richmond Ave, Houston, TX 77006
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https://oilwellcbd.com/
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