The Complete Guide to Rick Simpson Oil (RSO) in Boone County, Illinois: Understanding the Tradition, the Science, and the Modern Evolution
If you’re reading this from Boone County — whether you’re in Belvidere, Poplar Grove, Capron, or out on one of the rural routes that wind through our corn and soybean fields — chances are you’ve heard about Rick Simpson Oil. Maybe you heard about it from a neighbor at the Boone County Fair, or from someone in your church group dealing with cancer, or from a veteran at the American Legion hall who’s managing PTSD. Maybe you’re a cancer patient yourself, searching online at 2 AM from your home near the Kishwaukee River, looking for something beyond what the doctors at Swedish American or OSF Saint Anthony have offered. Maybe you’re a farmer whose body’s breaking down from decades of physical work, or someone caring for a parent with dementia at the Boone County Council on Aging.
Wherever you’re coming from, we want you to have the full picture — not hype, not hope disguised as medicine, but real information grounded in the actual science, framed by the real history, and delivered with the same honesty we’d give our own families. That’s what this guide is for.
What Is Rick Simpson Oil, Really? The History Every Boone County Resident Should Know
Who Was Rick Simpson (And Why It Matters Here)
Rick Simpson wasn’t a doctor. He wasn’t a scientist. He was a power engineer from Nova Scotia — a tradesman, like so many of the hardworking people here in Boone County who keep our infrastructure running. In 1997, working at a hospital in Moncton, he fell from scaffolding and suffered a serious head injury. The aftermath — persistent tinnitus, dizziness, post-concussion symptoms that wouldn’t quit — is something we see right here in Boone County, whether from farm accidents, factory injuries, or construction work in Rockford’s industrial corridor.
The medical system failed him. Prescriptions didn’t help, or made things worse. When he asked his doctor about cannabis, the doctor refused. Sound familiar? That’s the same conversation happening right now in doctor’s offices from Belvidere to Harvard, Illinois.
Simpson’s interest deepened after he learned about a 1974 NIH study at the Medical College of Virginia that found THC slowed tumors in mice. That study became his North Star, even though — and this is crucial — those findings were never replicated in controlled human cancer trials. The 1974 study was a starting point, not a conclusion.
The 2003 Skin Cancer Story That Started It All
The pivotal moment came in 2003. Simpson claimed that three bumps on his arm, diagnosed as basal cell carcinoma, disappeared after he applied concentrated cannabis oil and covered them with bandages for four days. Here’s what you need to know: No independent medical verification exists. No biopsy confirmation. No peer-reviewed documentation. No clinical follow-up. This is personal testimony, not medical evidence.
Why does this matter for Boone County residents? Because we know how powerful personal stories are in tight-knit communities. When someone at the Boone County Farmers’ Market says cannabis oil helped their neighbor, that carries weight. We respect that weight. But we also have a responsibility to distinguish between personal testimony and clinical proof — because cancer patients in Boone County deserve honesty, not false certainty.
Simpson’s Crusade: Giving Oil Away for Free
After 2003, Simpson committed himself to producing and distributing oil — for free. He gave it away to cancer patients, chronic pain sufferers, people with diabetes, glaucoma, arthritis, depression, insomnia, and more. No charge. Ever. He claimed to help dozens of people in his community of Maccan, Nova Scotia.
His story went global through the 2005 documentary Run From The Cure, which was distributed freely online. Within cannabis communities worldwide — including here in northern Illinois — that film became many people’s first introduction to concentrated cannabis oil as medicine. The name “Rick Simpson Oil” stuck, even as the product itself evolved far beyond what Simpson originally made.
But his advocacy brought legal consequences. The Royal Canadian Mounted Police raided him in 2005 and 2009. He was charged with cultivation, possession, and trafficking. Eventually, he left Canada for Europe, living in Croatia and the Netherlands, continuing his advocacy from abroad. The legal conflict he faced — operating in a pre-legalization era — is important context for why modern, Farm Bill-compliant products like ours exist today.
What Simpson Got Right vs. What He Overstated
He got this right: He drew attention to cannabinoids as serious medicine when the world was ignoring them. He helped create the cultural and political conditions for the legal cannabis industry we have today. The term “RSO” is now the most recognized name for full-spectrum cannabis extract because of him.
He overstated this: The leap from preclinical signals to cancer cure claims. Encouraging patients to use RSO instead of proven cancer therapies carries genuine harm potential. Delayed treatment for treatable cancers is a documented concern in alternative medicine literature. The Boone County community needs to hear this clearly: No cannabis product has been proven to cure cancer in humans. The National Cancer Institute acknowledges cannabis research but does not endorse cannabis as a cancer treatment. The FDA has not approved any cannabis plant product for cancer.
We honor Simpson’s historical contribution. We also commit to evidence standards he couldn’t access in his era.
Traditional Rick Simpson Oil: What It Actually Was
Understanding what Simpson actually made is essential for Boone County residents evaluating products today. Traditional RSO was:
- Made from single high-THC indica strains — no standardization, every batch different
- Extracted with naphtha or 99% isopropyl alcohol — neither food-grade, with real residual solvent risks
- Fully decarboxylated by heat — all THCa converted to psychoactive THC, no potency choice
- Dark, tar-like, sticky oil — strong cannabis odor, possible solvent smell
- THC-dominant (60-90% estimated) — with unknown minor cannabinoid ratios
- Stripped of terpenes — the heat destroyed them
- Never lab-tested — no COAs, no cannabinoid quantification, no contaminant screening
The safety concerns are real. Naphtha can contain benzene and toluene. Incomplete solvent purging leaves toxic residues. Without lab testing, there’s no way to know what you’re consuming.
The 60-Gram Protocol: What Simpson Recommended
Simpson’s famous treatment plan was designed to deliver 60 grams of oil over 90 days. Here’s the breakdown:
Week 1: Rice-grain-sized dose (10-15mg) three times daily — about 30-45mg total per day
Weeks 2-5: Double every four days until reaching 1 gram (1,000mg) per day, divided into three doses
Weeks 5-12: Maintain 1 gram per day until all 60 grams are consumed
Post-protocol: 1-2 grams per month as maintenance
Important context for Boone County residents:
This protocol has never been validated in controlled trials. It assumes crude, unstandardized material with unknown potency. At peak dosing, patients consumed roughly 600-900mg of delta-9 THC daily — doses far exceeding anything studied clinically. The risks at those levels include severe intoxication, anxiety, panic, tachycardia, hypotension, and cannabis use disorder.
The protocol does not apply to modern formulated products. Our OilWell RSO delivers 553mg of total cannabinoids per mL across seven compounds, with only 90mg of delta-9 THC in the entire bottle. You cannot simply follow Simpson’s dosing schedule with our product. Responsible use requires a different approach, which we’ll detail later.
OilWell Cannabis: Who We Are and Why We Built This
From the Borderplex to the Texas Medical Center
OilWell Cannabis was founded by Colin Valencia in Houston, Texas. But his story starts in McAllen, Texas — right across the river from Reynosa, Mexico, in the Borderplex region. McAllen-Reynosa is one of the most economically challenged and dangerous areas along the border. Violence, cartel activity, poverty, and limited opportunities outside retail and healthcare. Many of Colin’s best friends have been killed or imprisoned because of the associated dangers. He faced every form of violence imaginable. By sixteen, he had to leave home for good.
Despite that environment, Colin chose cannabis over darker paths. He grew up in the traditional cannabis world pre-legalization, learning the plant intimately. He saw it as safer and more beneficial than the alternatives. Over time, he transitioned from those risky early ventures to creating a legal, legitimate business.
Later, Colin became a formally trained software engineer and did custom development work for Baylor College of Medicine in the Texas Medical Center — one of the most prestigious medical institutions in the world. That combination of deep cannabis plant knowledge plus medical-grade technical precision defines everything we do.
Bentley: The Dog Who Started It All
Our company’s origin story isn’t about a business plan. It’s about a dog named Bentley.
Bentley was more than a pet — he was family. When he fell seriously ill, veterinarians delivered the verdict no owner wants to hear: euthanasia was the only humane option. Bentley was paralyzed in his back legs. Pain medications would destroy his organs. The choice was painful prolonged decline or immediate mercy killing.
Giving up wasn’t an option. In a desperate search for alternatives, Colin stumbled upon CBD through a question that changed everything. A rescue worker named Jessica asked: “You’ve moved how many tons of weed and you’ve never heard of CBD?” Colin had cannabis experience, but it was recreational. He’d never explored therapeutic applications.
Determined to save Bentley, Colin learned to create CBD golden paste — a specialized cannabinoid formula for pets. It wasn’t a cure, but it was hope. And that hope delivered what veterinary medicine said was impossible: Bentley got up. He walked over and brought his ball to play. From paralyzed and facing euthanasia to fetching his ball. This wasn’t placebo — dogs don’t respond to placebo. This was cannabinoid medicine doing what pharmaceuticals could not.
Bentley lived another ten years, passing naturally at age twenty. During those years, Colin developed specialized formulas for every age-related condition Bentley faced:
- Neurodegeneration → led to understanding CBG’s neuroprotective properties and THCa’s PPARγ agonism for brain cell protection
- Dementia → led to CBC’s role in neurogenesis
- Glaucoma → led to THC’s CB1 agonism for intraocular pressure reduction
- Crippling arthritis → led to multi-pathway anti-inflammatory approaches using CBD, CBG, THCa, and beta-caryophyllene working through different receptor systems simultaneously
Single cannabinoids weren’t enough. Bentley’s evolving conditions required multi-cannabinoid synergy. That necessity — keeping a beloved companion alive — is why our RSO formula contains seven cannabinoids instead of one or two. It wasn’t a marketing decision. It was born from love and refined through ten years of real-world testing on a patient that mattered more than anything.
Colin’s Personal Battle: PTSD, Benzo Addiction, and Peace Gummies
Colin knows pharmaceutical dependence personally. He struggled with PTSD and benzodiazepine addiction. When he decided to break free from Xanax, he did it cold turkey — notoriously difficult and dangerous — using the cannabinoid knowledge he developed keeping Bentley alive.
The Peace Gummies formula was created during midnight experiments while fighting through benzo withdrawal. Today, we offer Peace Gummies (and a vape version) because that formula literally saved Colin’s life. He personally uses the vape form to manage his insomnia and severe PTSD.
This is not theoretical knowledge. Colin lived what RSO patients live: desperation for relief, failed pharmaceuticals, the discovery that cannabinoids work when pills do not.
Over time, the therapeutic benefits Colin discovered through Bentley became the core of his work. He developed formulas that doctors use for Crohn’s disease, IBS, ulcerative colitis, PTSD, benzo addiction, and insomnia. His focus has always been accessibility for everyone — including vegans, diabetics, and those with specific health needs.
Why ABC13 Houston Keeps Coming to Us
Between 2019 and 2023, ABC13 Houston — the ABC affiliate serving America’s fourth-largest city — featured Colin and OilWell in seven distinct news segments covering business, law, medicine, community health, and politics. Five different reporters sought us out. No other Houston cannabis operator appears with that frequency or breadth.
What this means for Boone County: Mainstream media validation from a major-market ABC affiliate is a credibility signal that transcends geography. When you’re evaluating RSO products online from your home in Boone County, you need to know you’re dealing with a real company that real journalists trust as an expert source.
The Through-Line of Our Media Record
Consistency: From 2019’s CBD business profile through Delta-8’s boom and bust, through COVID community initiatives, through personal revelations about cannabis conviction history, to 2023’s “Renaissance” framing — ABC13 returned to Colin as a primary source through every industry shift.
Breadth: The features span business reporting, consumer health education, product investigation, legal analysis, political commentary, and community advocacy. We speak to the full spectrum of cannabis issues.
Community Action: In August 2021, we gave away approximately $35,000 in product (1,000 caviar pre-rolls) to encourage COVID-19 vaccination. We coordinated with the city of Houston. No political strings attached. That’s documented evidence of our community-first philosophy.
Proactive Ethics: When Texas DSHS reclassified Delta-8 as Schedule I in October 2021, we removed all products before enforcement began and warned other operators who were unknowingly shipping what had become illegal narcotics. We absorbed a major revenue loss to act ethically.
Personal Stakes: The October 2022 feature revealed Colin’s personal marijuana conviction history. That transforms every quote. We’re not corporate outsiders. We’re people who’ve lived the consequences of cannabis criminalization and built a legal business with integrity.
Evolution: Colin’s language evolved from “local wholesaler” (2019) to industry authority (2021) to sector leader (2023). The media record tracks our growth alongside legal cannabis itself.
These features aren’t marketing. They’re independently produced, editorially controlled news segments that repeatedly identified Colin Valencia as the most credible voice in Houston’s legal cannabis industry. That recognition cannot be purchased — it can only be earned.
Our Four Core Principles (The OilWell RSO Philosophy)
1. Accessibility Over Gatekeeping
No medical card required. Age 21+ only. Anyone in Boone County who needs this can purchase it legally. We ship nationwide. We ship internationally to customers who verify local legality.
Rick Simpson believed medicine should be accessible to everyone. We built a distribution model that makes that real — not through illegal channels, but through Farm Bill-compliant hemp products that can reach your doorstep in Boone County legally.
2. Patient-Controlled Potency
Our sublingual formula contains 1,500mg of THCa in its acidic, non-psychoactive form. You decide:
-
Raw (no heat): All 1,500mg stays as THCa — completely non-psychoactive. Use it during the day without impairment. Drive to work in Belvidere. Operate machinery on your farm. Parent your kids. THCa’s potential anti-inflammatory activity via COX-2 inhibition and neuroprotective potential via PPARγ agonism are preserved [12].
-
Fully activated (home decarboxylation): Heat at 260°F for 45-60 minutes converts 1,500mg THCa → ~1,315mg delta-9 THC. Combined with the existing 90mg delta-9 THC, you get ~1,405mg total delta-9 THC. Plus our 6,000mg delta-8 THC. This achieves psychoactive potency comparable to traditional illegal RSO — 100% legally, because activation happens after purchase.
-
Vape (instant decarboxylation): Our vape cartridge vaporizes at 400-450°F, instantly converting THCa to delta-9 THC per puff.
Simpson believed patients should control their medicine. We engineered a product that puts that control in your hands through chemistry, not rhetoric.
3. Open-Source Formulas
We publish our complete formulas publicly — every cannabinoid, every milligram, every percentage. Why? Because if you can’t afford $129.99 for our sublingual oil or $49.99 for our vape cartridge, you can source individual distillates and make your own version.
This is a direct echo of Rick Simpson’s ethos. He gave oil away for free and taught people to make it. We sell a professionally manufactured, lab-tested, standardized product for those who want it, and we publish the recipe for those who want to DIY.
4. Evidence-Informed, Not Evidence-Overstating
The GENERAL KNOWLEDGE section you’re about to read represents our commitment to honest education about what science actually says. Simpson operated without peer-reviewed literature. We have that access, and we use it to distinguish what’s well-supported from what’s emerging from what’s overstated.
As Colin said on ABC13 in 2019: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.”
Farm Bill Compliance: The Legal Framework That Makes This Possible for Boone County
The 2018 Farm Bill legalized hemp and hemp-derived products containing less than 0.3% delta-9 THC by dry weight at the federal level. This is the foundation of our product design.
Our RSO Sublingual Oil contains only 90mg of delta-9 THC in the entire 30mL bottle (3mg per mL) — well under the 0.3% threshold. All cannabinoids are hemp-derived. The product is legal under federal law and in Illinois.
THCa is the key. It’s the acidic, non-psychoactive precursor to delta-9 THC. It’s not itself delta-9 THC, so it’s Farm Bill compliant at the point of sale. The customer controls conversion.
Important legal notice for Boone County residents: THCa converts to delta-9 THC when heated. You are responsible for understanding and complying with Illinois laws regarding cannabinoid products. We ship with full documentation, Certificates of Analysis, and receipts. International customers accept all customs and legal responsibility.
Currently, Boone County has no state-licensed adult-use cannabis dispensaries. Residents must travel to other counties (like nearby Winnebago County) to purchase from licensed dispensaries. Our direct-to-consumer shipping model eliminates that burden — Farm Bill-compliant hemp products can be shipped directly to your Boone County address.
The Science Behind Every Cannabinoid in Our Formula
Below is what peer-reviewed research actually says about each compound in our RSO formula. We’re not cherry-picking. We’re giving you the full evidence picture so you can make informed decisions.
CBD: The Most Studied Cannabinoid
Best supported: Purified CBD has the strongest human evidence for seizure disorders, particularly rare epilepsies [1][2]. This is the clearest major indication acknowledged by institutional literature.
Anxiety: A 2024 systematic review and meta-analysis of 316 participants across eight studies reported a statistically significant anxiolytic signal, but authors stress the clinical sample remains limited and more trials are needed [3].
Pain: A 2024 systematic review concluded the pain literature is promising but heterogeneous, with trial quality limiting broad analgesic claims [4].
Sleep: A 2023 insomnia review found the literature methodologically weak, relying heavily on non-validated subjective measures [5].
Safety: A 2023 systematic review found real signals for liver enzyme elevation and possible drug-induced liver injury, especially relevant for concentrated oral products and people taking multiple medications [6]. NCCIH also flags diarrhea, sleepiness, appetite changes, mood effects, and drug-drug interactions [1].
Bottom line for Boone County: CBD is the most evidence-developed non-intoxicating cannabinoid, but strong evidence is concentrated in specific indications rather than broad wellness claims.
CBG: The Promising Minor Cannabinoid
Evidence profile: Mostly review and preclinical; human evidence remains sparse [7][8].
Pharmacology: CBG is the biosynthetic precursor to major cannabinoids, with interactions spanning cannabinoid receptors, alpha-2 adrenoceptors, and 5-HT1A signaling — mechanistically interesting but not clinically established [7].
Research areas: Reviews discuss possible relevance to neurologic disorders, inflammatory bowel disease, and antibacterial activity, but these are pharmacology-led hypotheses, not mature therapeutic conclusions [7][8].
Caution: A 2021 review explicitly notes CBG is being sold commercially while the evidence base remains thin [7].
Bottom line for Boone County: CBG is a serious research topic but should be described as promising with limited clinical validation, not proven therapeutic.
Delta-8 THC: The THC Analogue
Evidence profile: Pharmacologically relevant, psychoactive, and much less clinically characterized than delta-9 THC [9]-[11].
Pharmacology: A 2022 review found delta-8 and delta-9 THC have broadly similar behavior. Delta-8 is a partial CB1 agonist with cannabimimetic activity, but appears less potent, likely due to weaker CB1 affinity [9].
Public health: A 2023 scoping review found the evidence base dominated by animal studies, product chemistry, and public-health concerns rather than strong human trials. It noted reports of adverse consequences and emphasized regulatory and quality concerns [10].
Manufacturing: A 2024 review noted commercial delta-8 interest is tied to greater stability and easier synthesis relative to naturally scarce plant levels, raising product-byproduct and lab-testing questions [11].
Bottom line for Boone County: Delta-8 THC is a psychoactive THC analogue with real effects but incomplete human safety characterization and manufacturing-quality uncertainty.
THCa: The Legal Game-Changer
Evidence profile: Important chemically for our formulation, but low on direct human therapeutic evidence [12].
What it is: THCa is the acidic precursor to THC and may represent a large share of THC-related content in raw plant material. The key issue: THCa decarboxylates into THC during heating and can change over time during storage and processing [12].
Psychoactivity: THCa itself does not produce THC’s psychoactive effects, but this distinction only holds if the molecule stays acidic and isn’t substantially decarboxylated [12].
Research status: In vitro and rodent literature suggest anti-inflammatory, immunomodulatory, neuroprotective, and antineoplastic possibilities, but these aren’t established human outcomes [12].
Bottom line for Boone County: THCa is a highly relevant precursor whose interpretation depends heavily on route, temperature, processing, and storage. Any THCa claim must account for possible conversion to THC.
Delta-9 THC: The Most Studied Psychoactive Cannabinoid
Evidence profile: Strongest human evidence of the psychoactive cannabinoids, but also clearest adverse-effect burden [1][13]-[15].
Best supported: NCCIH identifies THC-containing medicines as relevant for chemotherapy-related nausea/vomiting, HIV/AIDS appetite/weight loss, and some MS/pain outcomes, while stressing many other uses remain uncertain [1].
Pain: A 2022 systematic review found high-THC products or comparable THC:CBD ratios may provide short-term pain benefit but increase dizziness, sedation, nausea, and treatment discontinuation [13].
Pharmacokinetics: Inhaled THC produces effects within seconds to minutes, peaking in 15-30 minutes, tapering over hours. Oral THC has later onset, later peak, and longer duration — crucial for both benefit and overconsumption risk [14].
Mental health risk: A 2025 systematic review of high-concentration THC products found consistent unfavorable associations with psychosis/schizophrenia and cannabis use disorder, with concerning signals for anxiety and depression in non-therapeutic settings [15].
Broader safety: Literature describes anxiety/panic at high doses, tachycardia, blood pressure changes, dependency potential, withdrawal, pregnancy concerns, accidental pediatric exposure, and vape-related lung injury [1][14][15].
Bottom line for Boone County: Delta-9 THC has legitimate therapeutic relevance but carries clear intoxication, psychiatric, and dose-related safety liabilities.
CBN: The Sleep Cannabinoid (With Weak Evidence)
Evidence profile: Weak human evidence; marketing has moved ahead of data [12][16][17].
Marketing vs. reality: CBN is widely marketed for sleep/sedation, but clinical support is far thinner than the market suggests [16][17].
Sleep research: A 2021 narrative review screened 99 human-study abstracts, reviewed eight full-text articles, and found no clinical trials using validated sleep questionnaires or formal polysomnography that could substantiate strong sleep-promoting claims [16].
Broader sleep literature: A 2024 updated review concluded cannabinoid sleep research still doesn’t match real-world use scale, and better-designed, adequately powered trials remain needed [17].
Bottom line for Boone County: CBN is one of the clearest examples where cultural reputation exceeds clinical evidence. Specific sleep evidence remains weak and dated, with no strong validated-trial base yet identified.
CBC: The Emerging Minor Cannabinoid
Evidence profile: Emerging, intriguing, overwhelmingly preclinical or review-based [18][19].
Pharmacology: A 2024 focused review describes CBC as having distinct pharmacodynamics, pharmacokinetics, and receptor behavior relative to better-known cannabinoids, highlighting antinociceptive, antibacterial, and anti-seizure areas as interesting research targets [18].
Older literature: Review literature summarizing animal and in vitro work reports anti-inflammatory effects, reduced gut hypermobility, modest rodent analgesic activity, and possible neurobiological/antiproliferative relevance — not yet strong evidence for patient-facing claims [19].
Safety caveat: The 2024 CBC review explicitly notes over-the-counter CBC products are being sold despite little evidence establishing clinical efficacy or safety [18].
Bottom line for Boone County: CBC is a scientifically credible minor cannabinoid deserving more research, not an already-validated clinical active.
The Terpene Profile: Aroma, Flavor, and Plausible Biology
Terpene claims need stricter interpretation than cannabinoid claims. Much literature comes from isolated compounds, essential oils, non-cannabis plants, or preclinical models. Robust proof of clinically meaningful entourage effects in humans remains limited [20][29].
Our RSO includes live terpenes at 5% with this specific seven-terpene profile:
Limonene (Citrus-Bright)
- Evidence: Mostly review/preclinical [20]-[22]
- Activity: 2021 review describes antioxidant, anti-inflammatory, cardioprotective, gastroprotective, immune-modulatory possibilities — mostly from nonhuman/non-cannabis literature [21]
- Safety: Limonene oxidation products are clinically relevant contact allergens [22]
- Bottom line: Biologically active but cannabis-specific therapeutic claims should stay conservative
Myrcene
- Evidence: Mostly preclinical, very limited human evidence [20][23]
- Activity: 2021 review describes anxiolytic, antioxidant, anti-inflammatory, analgesic properties but explicitly states human studies are lacking [23]
- Caution: Often invoked as a proven sedative explaining “couch-lock” — stronger claim than human evidence supports [20][23]
- Bottom line: Plausible bioactive terpene, but compound-specific clinical claims about mood/pain/sedation remain far ahead of definitive proof
Caryophyllene (Pepper/Spice)
- Evidence: Among most mechanistically interesting due to CB2 receptor relevance, but mostly preclinical [24]
- Why it stands out: 2021 review describes beta-caryophyllene as a selective CB2 receptor agonist — unusual and pharmacologically relevant [24]
- Activity: Anti-inflammatory, immunomodulatory, antioxidant, neuroprotective, gastroprotective discussed in reviews, but human clinical confirmation limited [24]
- Bottom line: Strongest candidate for terpene with cannabinoid-system significance, but not clinically proven for common attributed outcomes
Pinene (Forest-Fresh)
- Evidence: Promising preclinical, weak human confirmation [20][25]
- Activity: 2021 review on pinene and linalool found antioxidant, anti-inflammatory, neuroprotective signals justifying future study, but emphasized lack of well-designed clinical trials [25]
- Caution: Claims that pinene reliably improves memory, sharpens attention, or counterbalances THC cognitive effects remain hypotheses, not settled facts [20][25]
- Bottom line: Deserves scientific attention, but strong cognition-related claims should be presented as exploratory
Linalool (Floral, Lavender)
- Evidence: Substantial preclinical interest, limited direct clinical confirmation [20][22][25][26]
- Activity: Discussed for stress, mood, brain-health pharmacology. 2021 brain-health review found enough preclinical signal to justify continued neurological/psychiatric investigation while emphasizing lack of robust human trials [25]
- Additional literature: Separate reviews discuss possible antidepressant mechanisms and neuropharmacologic relevance, but this remains translational rather than definitive clinical [26]
- Safety: Oxidized linalool hydroperoxides are recognized allergens [22]
- Bottom line: Scientifically credible bioactive terpene, but current evidence supports cautious phrasing rather than firm therapeutic promises
Humulene (Earthy, Woody)
- Evidence: Translationally interesting, but early [20][27]
- Activity: 2024 scoping review analyzing 340 articles found broad preclinical evidence for anti-inflammatory and other effects, with some rodent work suggesting cannabimimetic properties via CB1 and adenosine A2a pathways [27]
- Caution: Findings are valuable for hypothesis generation but don’t yet establish consistent human efficacy across pain, inflammation, or mood outcomes [27]
- Bottom line: One of the more interesting terpene research targets, but far from clinically settled
Terpinolene (Piney, Fruity, Sparkling)
- Evidence: One of least clinically characterized terpenes in this file [20][28]
- Activity: 2021 systematic review screened 2,449 records, included 57 studies, concluding terpinolene has reported biological effects but evidence base dominated by in silico, in vitro, and animal studies rather than human trials [28]
- Bottom line: Biologically interesting, but among listed terpenes remains especially underdeveloped clinically
Research Limits and How to Interpret Claims
Five critical rules for evaluating cannabis information:
-
Evidence is highly uneven. CBD and delta-9 THC support most detailed human statements; others require more caution [1]-[29].
-
Extract/molecule/synthetic/terpene data aren’t interchangeable. A common error is letting evidence from one category stand for another. Don’t do this.
-
Minor cannabinoids and terpenes are commercially interesting precisely because they’re underexplored — but that means claims often become inflated.
-
Product quality matters as much as molecule identity. Labeling inaccuracies, contamination, synthesis byproducts, dose variability, and route-dependent pharmacokinetics all materially affect real-world products [1][10][11][14].
-
THCa chemistry changes with storage and heating. Storage and heating can convert acidic cannabinoids into neutral cannabinoids like THC, changing actual exposure profiles [12].
Common Overstatements to Avoid (And What to Say Instead)
| Overstatement | More Accurate Statement |
|---|---|
| CBN is a clinically proven sleep cannabinoid | The specific sleep evidence for CBN remains weak and dated, with no strong validated-trial base yet identified [16][17] |
| Myrcene is a proven human sedative that reliably explains couch-lock | Myrcene has plausible preclinical bioactivity, but direct human proof for that common claim is limited [20][23] |
| Terpenes in general have proven entourage effects in patients | Entourage hypotheses are influential and worth studying, but robust clinical proof remains limited and highly compound-specific [20][29] |
| THCa is always nonpsychoactive | THCa itself is not THC, but heating and processing can convert THCa into THC, changing effective exposure [12] |
| Delta-8 THC is safe because it’s hemp-derived | Delta-8 THC is psychoactive, pharmacologically close to delta-9 THC, and often entangled with manufacturing and testing concerns [9]-[11] |
Our Formulas: Complete Transparency
This is what no other RSO company publishes. We’re giving you the exact recipe — because you deserve to know what you’re putting in your body, and because if you can’t afford our product, you deserve the ability to make it yourself.
RSO Sublingual Oil — $129.99
| Cannabinoid | Amount |
|---|---|
| CBD | 4,500mg |
| CBG | 3,000mg |
| Delta-8 THC | 6,000mg |
| THCa | 1,500mg |
| Delta-9 THC | 90mg |
| CBN | 750mg |
| CBC | 750mg |
| Total Cannabinoids | 16,590mg |
- Live Terpenes: 5% (limonene, myrcene, caryophyllene, pinene, linalool, humulene, terpinolene)
- Carrier: Organic MCT oil
- Format: 30mL bottle with graduated dropper (0.1mL increments)
- Active cannabinoids per mL: 553mg
- Approximate doses per bottle: 40-60 depending on serving size
What this means for Boone County: At 553mg/mL, this is one of the most concentrated legal hemp products available. A single 0.25mL dose delivers 138mg of total cannabinoids — substantial therapeutic potential. Compare this to typical CBD oils at 16-50mg/mL.
RSO Vape Cartridge — $49.99
| Cannabinoid | Percentage |
|---|---|
| CBD | 30% |
| CBG | 20% |
| Delta-8 THC | 15% |
| THCa | 10% |
| CBN | 10% |
| CBC | 10% |
- Live Terpenes: 5%+
- Format: 1 Gram cartridge (510-thread universal battery compatible)
- Total cannabinoids: 900mg+
What this means for Boone County: When you need fast relief — breakthrough pain, panic attack, nausea from chemo — the vape delivers effects in 1-2 minutes. That’s crucial for acute situations where waiting 45 minutes for sublingual onset isn’t an option.
When to Use Each Format: A Practical Guide for Boone County Residents
| Your Situation | Recommended Format | Why |
|---|---|---|
| Fast relief needed (acute pain flare-up, panic attack, chemo nausea) | Vape cartridge | 1-2 minute onset [14] |
| Sustained daily relief (chronic pain, sleep maintenance) | Sublingual oil | 4-6 hour duration [14] |
| Maximum absorption | Sublingual oil | 13-19% bioavailability (partially bypasses liver) [14] |
| Portability/discretion | Vape cartridge | Compact, no measuring needed |
| Precise dosing control | Sublingual oil | Graduated dropper in 0.1mL increments |
| Daytime use, must function (work, drive, parent) | Sublingual oil (raw, no heat) | THCa stays non-psychoactive |
| Nighttime, want full effects | Sublingual oil (decarbed) or vape | Activated THC + CBN for sleep |
Condition-Specific Usage Context for Boone County Residents
Critical disclaimer: These contexts are informed by cannabinoid research cited throughout this guide and by our formulation rationale. They are NOT medical prescriptions, NOT FDA-approved treatment protocols, and NOT substitutes for professional medical care. These products have not been evaluated by the Food and Drug Administration and are not intended to diagnose, treat, cure, or prevent any disease. Always consult a qualified healthcare provider before using cannabinoid products, especially if you have a medical condition, take medications, are pregnant or nursing, or have health concerns. Do not operate vehicles or machinery while under the influence of psychoactive cannabinoids.
Chemotherapy-Related Nausea and Appetite Support
Pre-chemo: 0.5-1.0mL sublingual approximately 1 hour before treatment
Acute breakthrough nausea: 2-3 vape puffs for immediate relief (1-2 minute onset)
Post-chemo: 0.5mL sublingual every 6 hours as needed
Sleep support during treatment: 1.0-2.0mL sublingual before bed (delivers 25-50mg CBN)
Evidence context: Delta-8 THC antiemetic evidence [9], delta-9 THC nausea/vomiting evidence [1][13], CBD anxiolytic buffering [3]
Chronic Pain (Fibromyalgia, Arthritis, Neuropathy, Back Pain from Farm Work)
Daytime: 0.3-0.5mL raw sublingual — anti-inflammatory cannabinoid exposure without psychoactive impairment (you can operate your tractor, work in your shop, drive to Rockford)
Nighttime: 0.5-1.0mL decarboxylated sublingual — combines pain relief with CBN sleep support
Breakthrough pain: Vape as needed for rapid onset
Evidence context: CBD pain evidence [4], delta-9 THC pain evidence [13], beta-caryophyllene CB2 agonism [24], THCa COX-2 inhibition [12]
Sleep Support (Insomnia, Disrupted Sleep from Pain or Anxiety)
Before bed: 1.0-2.0mL sublingual
- At 2.0mL, this delivers 50mg CBN — the dosage investigated in 2024 sleep literature
- At 1.0mL, this delivers 25mg CBN — above the 20mg threshold associated with reduced sleep disturbance in published research
Evidence context: CBN sleep evidence [16][17], cannabis and sleep review literature
Anxiety and Stress (Including PTSD for Boone County Veterans)
Daytime functional relief: 0.3mL raw sublingual — CBD and CBG address anxiety pathways without impairment (compatible with work, driving, parenting)
Nighttime: 1.0mL sublingual — full cannabinoid profile including CBN for sleep architecture
Evidence context: CBD anxiety evidence [3], CBG pharmacology [7][8], limonene entourage-effect evidence [20]
General Titration Principle: Start Low, Go Slow
Begin with 0.25-0.5mL sublingual (138-276mg total cannabinoids). Assess effects over 2-3 hours before increasing. Individual responses vary based on body weight, metabolism, tolerance, concurrent medications, and other factors.
This is NOT Simpson’s protocol. Our product is fundamentally different — standardized, multi-cannabinoid, and precisely dosed. Do not attempt to follow the 60-gram/90-day schedule with our formula. That protocol was designed for crude, unknown-potency oil and is not appropriate for modern formulated products.
How Boone County Residents Can Access Our Products
Houston Same-Day Delivery (For Context)
We operate the only same-day RSO delivery system in Houston. This showcases our infrastructure capabilities:
- Texas Medical Center: FREE delivery (MD Anderson, Memorial Hermann, Methodist, Texas Children’s)
- Inner Loop (610): $5 delivery
- Within Beltway 8: $10 delivery
- Greater Houston suburbs: $15 delivery
- Extended region (60 miles): $20-25 delivery
Nationwide Shipping to Boone County, Illinois
Since Boone County currently has no state-licensed adult-use cannabis dispensaries, our direct shipping model is your most convenient legal access point.
Shipping options:
- USPS Priority Mail: 2-3 business days
- FedEx/UPS Ground: 3-5 business days
- Discreet packaging: No cannabis branding visible
- Tracking: Provided for all orders
- Temperature-stable packaging: For summer shipments (crucial during Boone County’s humid summers)
- Signature-required option: Available
International Shipping
We’ve delivered to multiple countries across continents. The THCa legal framework makes this possible: less than 0.3% delta-9 THC at point of sale meets the Farm Bill definition, enabling shipping to jurisdictions with compatible hemp laws.
For international orders: All packages include full documentation, Certificates of Analysis, and customs receipts. Customer accepts all customs and legal responsibility.
The Evidence Hierarchy: Understanding Research Quality
When evaluating cannabis claims, this is the hierarchy we use:
- Human clinical evidence (randomized controlled trials)
- Systematic reviews and meta-analyses
- NIH and other institutional summaries
- Mechanistic or preclinical literature (animal studies, in vitro)
This matters because the evidence base is uneven. CBD and delta-9 THC can support detailed human-facing statements; others require more caution.
Our Media Record: Seven ABC13 Features, Four Years, Five Reporters
September 15, 2019: “Texas CBD businesses booming” — Tom Abrahams
Colin’s foundational quote: “I’m not trying to sell people snake oil. I’m not trying to sell people hope, but there’s enough research out there that people just need to know and try and have the best possible version to base their opinions off of to give it a fair shot as to whether it’s right or wrong for them.”
March 22, 2021: “Entrepreneur creates direct-to-consumer business” — Tom Abrahams
Colin on real pain: “Pain comes in a lot of different forms.”
May 24, 2021: “What is Delta 8 THC” — Steve Campion
Campion: “Why would someone want to smoke that?”
Colin: “I don’t give a sh* if it’s wrong to say you’ll get high off it. Maybe you want to get high.”*
August 20, 2021: “Houston CBD shop giving away free products for COVID vaccine” — KTRK Staff
We gave away ~$35,000 in product (1,000 caviar pre-rolls) to encourage vaccination. No political agenda. We coordinated with the city of Houston.
October 19, 2021: “Texas ban over once legal hemp product Delta 8” — Shelley Childers
We proactively removed all Delta-8 products before enforcement and warned other operators. Colin: “So those people are now, because they didn’t know, shipping Schedule 1 narcotics, and people are receiving it.”
October 7, 2022: “Biden marijuana pardon — experts weigh in” — Nick Natario
Colin revealed his personal marijuana conviction history: “You face challenges with housing, loans, and banking, I mean with about everything. I would love to see people not get hurt for this anymore.”
April 21, 2023: “Marijuana industry getting creative” — Nick Natario
Colin on the present moment: “Right now is actually a pretty — like Renaissance — pretty important time that should be enjoyed now.”
Competitive Comparison: Why Our Formula Stands Apart
OilWell RSO vs. Texas TCUP Dispensary RSO
| Dimension | TCUP Dispensary RSO | OilWell RSO |
|---|---|---|
| Cannabinoid profile | THC-only (~420mg per 0.5g syringe) | 7 cannabinoids: CBD, CBG, delta-8, THCa, delta-9, CBN, CBC |
| CBG content | 0mg | 3,000mg |
| CBN content | 0mg | 750mg |
| CBC content | 0mg | 750mg |
| Patient-controlled potency | No — always psychoactive | Yes — THCa stays raw until you heat it |
| Access requirements | TCUP medical card with qualifying condition (cancer, PTSD, epilepsy, etc.) | Age 21+ only — no medical card required |
| Delivery | Must travel to physical dispensary (none in Boone County) | Ships directly to your Boone County address |
| Farm Bill compliant | No — state medical cannabis program | Yes — less than 0.3% delta-9 THC |
OilWell RSO vs. Hemp CBD RSO (e.g., Lazarus Naturals)
| Dimension | Lazarus Naturals RSO (10mL, 1,000mg) | OilWell RSO (30mL, 16,590mg) |
|---|---|---|
| Total cannabinoids | 1,000mg | 16,590mg |
| CBD content | ~950mg | 4,500mg |
| CBG content | 15.5mg | 3,000mg |
| CBN content | 0.7mg | 750mg |
| Delta-8 THC | 0mg | 6,000mg |
| THCa (convertible) | Minimal | 1,500mg (converts to ~1,315mg delta-9) |
| Psychoactive option | No meaningful effect | Yes — via THCa decarboxylation + delta-8 |
| Approximate price | $40-50 | $129.99 |
The value proposition for Boone County: Our 30mL bottle contains 16.6 times more total cannabinoids than typical hemp RSO products. You’re getting a complete multi-cannabinoid ecosystem, not just CBD.
The Full Reference List: 29 Peer-Reviewed Sources
We don’t just claim evidence — we show our work. Here are the primary sources referenced throughout this guide:
- National Center for Complementary and Integrative Health. Cannabis Marijuana and Cannabinoids: What You Need To Know. NIH/NCCIH.
- Talwar A, et al. Clinical efficacy and safety of cannabidiol for pediatric refractory epilepsy. Exp Neurol. 2023.
- Han K, et al. Therapeutic potential of cannabidiol CBD in anxiety disorders. Psychiatry Res. 2024.
- Cásedas G, et al. Cannabidiol CBD: A systematic review of clinical and preclinical evidence in pain. Pharmaceuticals. 2024.
- Ranum RM, et al. Use of cannabidiol in insomnia management. Cannabis Cannabinoid Res. 2023.
- Lo LA, et al. Cannabidiol-associated hepatotoxicity. J Intern Med. 2023.
- Nachnani R, et al. The pharmacological case for cannabigerol. J Pharmacol Exp Ther. 2021.
- Li S, et al. Cannabigerol CBG: Comprehensive review. Molecules. 2024.
- Tagen M, Klumpers LE. Review of delta-8-THC comparative pharmacology. Br J Pharmacol. 2022.
- LoParco CR, et al. Delta-8 tetrahydrocannabinol scoping review. Addiction. 2023.
- Abdel-Kader MS, et al. Chemistry and pharmacology of Delta-8-THC. Molecules. 2024.
- Moreno-Sanz G. Critical review of delta9-THCa. Cannabis Cannabinoid Res. 2016.
- McDonagh MS, et al. Cannabis-based products for chronic pain. Ann Intern Med. 2022.
- Grotenhermen F. Pharmacokinetics and pharmacodynamics of cannabinoids. Clin Pharmacokinet. 2003.
- Rittiphairoj T, et al. High-concentration delta-9-THC products and mental health. Ann Intern Med. 2025.
- Corroon J. Cannabinol and sleep. Cannabis Cannabinoid Res. 2021.
- Lavender I, et al. Using cannabis and CBD to sleep. Curr Psychiatry Rep. 2024.
- Sepulveda DE, et al. Potential of cannabichromene. J Pharmacol Exp Ther. 2024.
- Zagožen M, et al. Cannabigerol and cannabichromene in Cannabis sativa. Acta Pharm. 2021.
- André R, et al. The entourage effect in cannabis medicinal products. Pharmaceuticals. 2024.
- Anandakumar P, et al. D-limonene therapeutic effects. J Food Biochem. 2021.
- Ogueta IA, et al. Limonene and linalool hydroperoxides review. Contact Dermatitis. 2022.
- Surendran S, et al. Myrcene: Health benefits review. Front Nutr. 2021.
- Hashiesh HM, et al. CB2 receptor-selective properties of beta-caryophyllene. Biomed Pharmacother. 2021.
- Weston-Green K, et al. Pinene and linalool for brain health. Front Psychiatry. 2021.
- Dos Santos ÉRQ, et al. Linalool as therapeutic tool in depression. Curr Neuropharmacol. 2022.
- Dalavaye N, et al. Clinical translation of alpha-humulene. Planta Med. 2024.
- Menezes IO, et al. Biological properties of terpinolene. Phytomedicine. 2021.
- Russo EB. Taming THC: Entourage effects. Br J Pharmacol. 2011.
The Bentley Recipe: Our Original Open-Source Formula
Before we published RSO formulas, we published the CBD golden paste recipe that saved Bentley — so any pet owner facing a similar crisis could make it themselves.
Ingredients:
- 1/2 cup organic turmeric powder
- 1 cup water
- 1/3 cup coconut oil (unrefined, organic)
- 1-2 teaspoons freshly ground black pepper (crucial for absorption)
- CBD oil (dosage depends on pet size; consult veterinarian)
Instructions:
- Mix turmeric and water in saucepan, stir over low heat until thick paste forms (7-10 minutes)
- Add coconut oil and pepper, stir thoroughly
- Cool, transfer to jar, refrigerate up to 2 weeks
- Mix small amount with pet’s food 1-2x daily
Serving suggestion: Start with low dose, monitor changes, consult veterinarian.
This was our first open-source act. The RSO formulas continue that pattern.
Final Thoughts for Boone County
We wrote this guide because we believe people in Boone County — whether you’re dealing with cancer, chronic pain from years of physical labor, PTSD from military service, anxiety that keeps you up at night, or simply curiosity about cannabinoids — deserve the same level of honest, evidence-based education that we’d give our own families.
We know that trust is earned, not given. We know that in communities like Boone County, where relationships and word-of-mouth matter more than slick marketing, our only option is to be relentlessly honest.
We also know that many of you are facing situations where conventional medicine has come up short. Maybe you’re at FHN Memorial Hospital in Freeport and hearing “there’s nothing more we can do.” Maybe you’re at the VA clinic in Rockford and struggling to get adequate pain management. Maybe you’re watching a loved one decline at a nursing home in Belvidere and searching for anything that might help.
We’ve been there. Bentley taught us that desperation can lead to discovery. Colin’s own PTSD taught us that pharmaceuticals aren’t always the answer. Our commitment is to give you the best possible information so you can make informed decisions for yourself and your family.
We’re not saying cannabis is right for everyone. We’re saying you deserve the truth about what it is, what it can and cannot do, and how to access it safely and legally.
From our family in Houston to yours in Boone County: we’re here to help.
Contact and Ordering Information
- Phone: (832) 416-2816
- Email: [email protected]
- Website: https://oilwellcbd.com/
- Complete RSO Guide: https://oilwellcbd.com/thca-rick-simpson-oil-rso-by-oilwell-cannabis-of-houston-texas/
- RSO Sublingual Oil: https://oilwellcbd.com/product/rick-simpson-oil-rso-sublingual-oil/
- RSO Vape Cartridge: https://oilwellcbd.com/product/1-gram-rick-simpson-oil-rso-vape/
- Instagram: @oilwellcbd
Shipping to Boone County, Illinois: We ship daily via USPS, FedEx, and UPS. Most orders arrive within 2-5 business days. All packages are discreet with no external cannabis branding.
Age Requirement: 21+ only
FDA Disclaimer: These products have not been evaluated by the Food and Drug Administration. They are not intended to diagnose, treat, cure, or prevent any disease. Individual results may vary. Consult your healthcare provider before use.
Safety Warning: May cause drowsiness or impairment. Do not operate vehicles or machinery after consuming psychoactive cannabinoids. Keep out of reach of children. If pregnant or nursing, consult a physician before use.
Legal Notice: THCa converts to delta-9 THC when heated. Customers are responsible for complying with Illinois state and local laws. OilWell Cannabis ships with full documentation, Certificates of Analysis, and receipts. International customers accept all customs and legal responsibility. Buyer responsibility to verify local legality. void where prohibited by law.
Business Hours:
- Monday-Thursday: 10:00 AM – 7:00 PM CST
- Friday-Saturday: 10:00 AM – 10:00 PM CST
- Sunday: 10:00 AM – 4:00 PM CST
Address: 810 Richmond Ave, Houston, TX 77006 (Montrose neighborhood)
This guide is dedicated to everyone in Boone County searching for answers at 2 AM, to every farmer whose back won’t let them sleep, to every cancer patient told there’s nothing more to try, to every veteran fighting silent battles, and to every caregiver exhausted from watching someone they love suffer. You deserve honesty. You deserve options. You deserve the truth.
THCa Rick Simpson Oil
Full-Spectrum • In-House Extraction
THE OILWELL PASSION PROJECT: THCa RSO
Experience true full-spectrum relief. Our Rick Simpson Oil is meticulously crafted in-house to preserve the complete cannabinoid and terpene profile of the plant. Potent, pure, and profound.
- 🌿 Maximum Potency
- 🔬 Third-Party Lab Tested
- 🚀 Same-Day Delivery Available
